List of works - Sarah Croessmann

A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations.

scientific article

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

scientific article published on 26 March 2019

Analysis of BRCA2 loss of heterozygosity in tumor tissue using droplet digital polymerase chain reaction.

scientific article

Combined blockade of activating mutations and ER results in synthetic lethality of ER+/HER2 mutant breast cancer

scientific article published on 12 October 2018

Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA.

scientific article

Detection of cancer DNA in plasma of patients with early-stage breast cancer.

scientific article

ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients

scientific article published on 10 August 2015

Extended adjuvant therapy with neratinib plus fulvestrant blocks ER/HER2 crosstalk and maintains complete responses of ER+/HER2+ breast cancers: Implications to the ExteNET trial

article

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

scientific article

HER2 missense mutations have distinct effects on oncogenic signaling and migration.

scientific article in 2015

Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer.

scientific article published on 3 August 2016

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation.

scientific article published on 28 January 2016

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.

scientific article

NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability

scientific article

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

scientific article published on 28 December 2017

PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.

scientific article published on 11 February 2017

Pathogenic Germline Variants in Patients With Metastatic Breast Cancer

scientific article published on 29 August 2019

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer

scientific article published on 23 December 2015

The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies

scientific article published in 2018

Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component

scientific article published on 19 April 2017

List of works by Sarah Croessmann

A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations.

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Analysis of BRCA2 loss of heterozygosity in tumor tissue using droplet digital polymerase chain reaction.

Combined blockade of activating mutations and ER results in synthetic lethality of ER+/HER2 mutant breast cancer

Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA.

Detection of cancer DNA in plasma of patients with early-stage breast cancer.

ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients

Extended adjuvant therapy with neratinib plus fulvestrant blocks ER/HER2 crosstalk and maintains complete responses of ER+/HER2+ breast cancers: Implications to the ExteNET trial

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

HER2 missense mutations have distinct effects on oncogenic signaling and migration.

Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer.

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation.

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.

NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.

Pathogenic Germline Variants in Patients With Metastatic Breast Cancer

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer

The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies

Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component