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List of works by Takeo Yoshikawa

11CDoxepin binding to histamine H1 receptors in living human brain: reproducibility during attentive waking and circadian rhythm ⬇️

scientific article published on June 11, 2012

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

scientific article published on 5 November 2015

Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.

scientific article published on 14 September 2017

Analysis of brain histamine clearance using genetically engineered mice

scientific article published on 01 January 2018

Angiotensin II receptor blockers differentially affect CYP11B2 expression in human adrenal H295R cells.

scientific article published on 12 December 2013

Characterization of murine polyspecific monoamine transporters.

scientific article published on 9 January 2017

Coffee treatment prevents the progression of sarcopenia in aged mice in vivo and in vitro.

scientific article published on 22 November 2013

Correlations of (18)F-THK5351 PET with post-mortem burden of tau and astrogliosis in Alzheimer's disease.

scientific article published in September 2017

Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression.

scientific article published on 29 December 2015

G-cell hyperplasia of the stomach induces ECL-cell proliferation in the pyloric glands in a paracrinal manner.

scientific article

Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion

scientific article published on 29 March 2018

Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis

scientific article published on 24 July 2021

Histamine -Methyltransferase in the Brain ⬇️

scientific article published on 10 February 2019

Histamine Clearance Through Polyspecific Transporters in the Brain

scientific article published on 28 September 2016

Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers.

scientific article

Histamine H1 receptor on astrocytes and neurons controls distinct aspects of mouse behaviour

scientific article published on 11 November 2019

Histamine H3 receptor in primary mouse microglia inhibits chemotaxis, phagocytosis, and cytokine secretion.

scientific article published on 10 March 2015

Histamine N-methyltransferase regulates aggression and the sleep-wake cycle.

scientific article published on 21 November 2017

Histamine elicits glutamate release from cultured astrocytes

scientific article published on 16 May 2018

Histaminergic Neurons in the Tuberomammillary Nucleus as a Control Centre for Wakefulness

scientific article published on 03 August 2020

Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate ⬇️

scientific article published on March 16, 2012

In vivo detection of amyloid plaques in the mouse brain using the near-infrared fluorescence probe THK-265

scientific article published on 01 January 2011

Induced histamine regulates Ni elution from an implanted Ni wire in mice by downregulating neutrophil migration.

scientific article published on 13 February 2017

Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice

scientific article

Involvement of the histamine H1 receptor in the regulation of sympathetic nerve activity.

scientific article published on 11 February 2015

JNJ10181457, a histamine H3 receptor inverse agonist, regulates in vivo microglial functions and improves depression-like behaviours in mice

scientific article published on 16 May 2017

Mechanism of the histamine H(3) receptor-mediated increase in exploratory locomotor activity and anxiety-like behaviours in mice

scientific article

Molecular mechanism of histamine clearance by primary human astrocytes.

scientific article published on 15 March 2013

Optically active iodohelicene derivatives exhibit histamine N-methyl transferase inhibitory activity

scientific article published on 20 November 2018

Positron emission tomography evaluation of sedative properties of antihistamines ⬇️

scientific article published on April 27, 2011

Predominant role of plasma membrane monoamine transporters in monoamine transport in 1321N1, a human astrocytoma-derived cell line

scientific article published on 13 February 2014

Retinoic acid receptor-α up-regulates proopiomelanocortin gene expression in AtT20 corticotroph cells

scientific article published on 14 August 2014

Role of histamine H3 receptor in glucagon-secreting αTC1.6 cells

scientific article

Site-Specific Labeling of F-18 Proteins Using a Supplemented Cell-Free Protein Synthesis System and O-2-[18F]Fluoroethyl-L-Tyrosine: [18F]FET-HER2 Affibody Molecule

scientific article published on 01 June 2019

Synthesis and Characterization of ¹⁸F-Interleukin-8 Using a Cell-Free Translation System and 4-¹⁸F-Fluoro-L-Proline.

scientific article published on 7 January 2016

Synthesis of [11C]interleukin 8 using a cell-free translation system and L-[11C]methionine

scientific article published on 29 September 2011

The clinical pharmacology of non-sedating antihistamines.

scientific article

The expression and function of histamine H₃ receptors in pancreatic beta cells.

scientific article published on January 2014

The reduction of heparan sulphate in the glomerular basement membrane does not augment urinary albumin excretion.

scientific article

Use of a benzimidazole derivative BF-188 in fluorescence multispectral imaging for selective visualization of tau protein fibrils in the Alzheimer's disease brain.

scientific article published in February 2014

Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase

scientific article published on 22 May 2018

[(18)F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.

scientific article published on 20 March 2015

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