List of works - Fuminori Tokunaga

A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors

scientific article published on 04 June 2020

A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

scientific article published on 6 October 2015

Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells

scientific article published on 22 September 2011

An autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response

scientific article published on 23 January 2015

Decreased linear ubiquitination of NEMO and FADD on apoptosis with caspase-mediated cleavage of HOIP.

scientific article published on 9 February 2017

Direct Virus Inactivation of Tachyplesin I and Its Isopeptides from Horseshoe Crab Hemocytes ⬇️

scientific article published on January 1, 1991

Endoplasmic reticulum stress in the pathogenesis of pretibial dystrophic epidermolysis bullosa

scientific article published on 27 August 2017

Generalized verrucosis caused by various human papillomaviruses in a patient with GATA2 deficiency.

scientific article published on 27 November 2017

Generation of Rat Monoclonal Antibodies Against a Deubiquitinase, Ovarian Tumor Domain-Containing Protein 1

scientific article published on 21 August 2018

Generation of Rat Monoclonal Antibodies Specific for DZIP3

scientific article published on 29 May 2018

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

scientific article

High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors Using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System

scientific article published on 02 August 2018

Identification of linear polyubiquitin chain immunoreactivity in tau pathology of Alzheimer's disease

scientific article published on 15 March 2019

Identification of one base deletion in exon IX of the protein C gene that causes a type I deficiency

scientific article published on 01 December 1992

In-frame Val216-Ser217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response.

scientific article published on 21 March 2018

Intracellular degradation of secretion defect‐type mutants of antithrombin is inhibited by proteasomal inhibitors ⬇️

scientific article published on July 21, 1997

Isolation and characterization of a thermolabile β-2 macroglycoprotein (‘thermolabile substance’ or ‘Hakata antigen’) detected by precipitating (auto) antibody in sera of patients with systemic lupus erythematosus ⬇️

scientific article published on July 12, 1991

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

scientific article published on 10 June 2015

Linear Polyubiquitin Chain Modification of TDP-43-Positive Neuronal Cytoplasmic Inclusions in Amyotrophic Lateral Sclerosis

scientific article published on 01 March 2020

Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction ⬇️

scientific article published on February 4, 2011

Linear Ubiquitin Code: Its Writer, Erasers, Decoders, Inhibitors, and Implications in Disorders

scientific article published on 11 May 2020

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

scientific article published on 24 August 2016

Linear ubiquitination-mediated NF- B regulation and its related disorders ⬇️

scientific article published on August 21, 2013

Linear ubiquitination: A novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex [Review] ⬇️

scientific article published on May 19, 2012

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

scientific article published on 03 April 2020

Molecular cloning of two types of cDNA encoding subunit RC6-I of rat proteasomes ⬇️

scientific article published on October 17, 1995

Preparation and properties of monoclonal antibodies against lipopolysaccharide-sensitive serine protease zymogen, factor C, from horseshoe crab (Tachypleus tridentatus) hemocytes ⬇️

scientific article published on October 1, 1992

Purified horseshoe crab factor G. Reconstitution and characterization of the (1-->3)-beta-D-glucan-sensitive serine protease cascade

scientific article published in 1995

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

scientific article published on 07 October 2013

Reduced SHARPIN and LUBAC Formation May Contribute to CCl₄- or Acetaminophen-Induced Liver Cirrhosis in Mice

scientific article published on 4 February 2017

Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling

scientific article published on 02 January 2019

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation