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Authors whose works are in public domain in at least one jurisdiction

List of works by Martin Schlee

5'-Triphosphate RNA is the ligand for RIG-I

scientific article (publication date: 10 November 2006)

A human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNA

scientific article

Abstract B44: Selective stimulation of RIG-I with a novel synthetic RNA induces strong anti-tumor immunity in mouse tumor models

Accessing the therapeutic potential of immunostimulatory nucleic acids

scientific article published on 30 July 2008

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

scientific article published on August 2004

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

scientific article

Approaching the RNA ligand for RIG-I?

scientific article published on January 2009

C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma

scientific article published on April 2007

Delivery with polycations extends the immunostimulant Ribomunyl® into a potent antiviral Toll-like receptor 7/8 agonist

article published in 2011

Discriminating self from non-self in nucleic acid sensing

scientific article

Enzymatic synthesis and purification of a defined RIG-I ligand

scientific article published on January 2014

Exosomes as nucleic acid nanocarriers

scientific article published on 28 June 2012

Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes

scientific article

G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes

scientific article published on 12 December 2016

Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA.

scientific article published on 20 July 2009

Human TLR8 Senses RNA From -Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV.

scientific article published on April 2004

Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells

scientific article

MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytes

scientific article published in January 2006

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

scientific article

Master sensors of pathogenic RNA – RIG-I like receptors ⬇️

scientific article published on July 1, 2013

Monocyte-Mediated Inhibition of TLR9-Dependent IFN- Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates

scientific article published on 05 November 2010

RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection

scientific article

RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation

scientific article

RIG-I activation induces the release of extracellular vesicles with antitumor activity

scientific article published on 19 August 2016

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

scientific article published on 12 October 2012

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells

scientific article

RNA recognition via TLR7 and TLR8.

scientific article published on January 2008

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

scientific article

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

scientific article

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

scientific article

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

scientific article published on 10 April 2009

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

scientific article

SiRNA delivery with exosome nanoparticles

scientific article published in April 2011

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system

scientific article

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

scientific article

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

scientific article published on June 2013

The chase for the RIG-I ligand--recent advances

scientific article published on 11 May 2010

c-MYC impairs immunogenicity of human B cells

scientific article published on January 2007

c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells

scientific article published on 04 March 2009

siRNA and isRNA: two edges of one sword

scientific article published on 31 July 2006

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