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List of works by Christian Wolfrum

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

scientific article published in September 2017

A family with severe insulin resistance and diabetes due to a mutation in AKT2.

scientific article

A high-throughput, image-based screen to identify kinases involved in brown adipocyte development

scientific article published on 14 February 2017

A radical opposition in body weight control ⬇️

scientific article published on August 1, 2013

A stromal cell population that inhibits adipogenesis in mammalian fat depots

scientific article published in Nature

Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice

scientific article published on 22 December 2016

Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape

scientific article published in 2024

Adipocytes at the Core of Bone Function

scientific article published in June 2017

Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma

scientific journal article

Adipose Tissue Stem Cells

scientific article published on 26 April 2015

Adipose tissue retains an epigenetic memory of obesity after weight loss

scientific article published on 18 November 2024

Adipose-derived circulating miRNAs regulate gene expression in other tissues

scientific article published on 15 February 2017

An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice

scientific article published on 29 August 2016

Anatomical Grading for Metabolic Activity of Brown Adipose Tissue

scientific article

Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis

scientific article

Bi-directional interconversion of brite and white adipocytes

scientific article

Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet

scientific article

Bone morphogenic proteins signaling in adipogenesis and energy homeostasis

scientific article published on 23 January 2013

Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells

scientific article published on 3 October 2002

Chronic high-fat diet impairs collecting lymphatic vessel function in mice

scientific article (publication date: 2014)

Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion

scientific article

Corrigendum: Adipose-derived circulating miRNAs regulate gene expression in other tissues.

scientific article

Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).

scientific article published in December 2002

Depot specific differences in the adipogenic potential of precursors are mediated by collagenous extracellular matrix and Flotillin 2 dependent signaling

scientific article

Effect of sex and bezafibrate on incorporation of blood borne palmitate into lipids of rat liver nuclei

scientific article published in 2000

Effectiveness of a low-calorie weight loss program in moderately and severely obese patients

scientific article published on 11 October 2013

Environmental and Nutritional Effects Regulating Adipose Tissue Function and Metabolism Across Generations.

scientific article published on 16 April 2019

Experimental study of metal nanoparticle synthesis by an arc evaporation/condensation process

FGF21, energy expenditure and weight loss - How much brown fat do you need?

scientific article

Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M

scientific journal article

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.

scientific article

GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1

scientific article published on 08 December 2021

Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors

scientific article (publication date: 2014)

Genetic modulation of the serotonergic pathway: influence on weight reduction and weight maintenance

scientific article published on 25 June 2013

Hairless promotes PPARγ expression and is required for white adipogenesis

scientific article

Harnessing a physiologic mechanism for siRNA delivery with mimetic lipoprotein particles

scientific article published on 5 June 2012

Hemostasis, endothelial stress, inflammation, and the metabolic syndrome

scientific article

Hepatic lipid composition differs between ob/ob and ob/+ control mice as determined by using in vivo localized proton magnetic resonance spectroscopy

scientific article published on 23 March 2012

Identification of a regulatory pathway inhibiting adipogenesis via RSPO2

scientific article published on 13 January 2022

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

scientific article

Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: The role of zinc-α2-glycoprotein

scientific article published on 17 December 2014

In-depth analysis of interreader agreement and accuracy in categorical assessment of brown adipose tissue in (18)FDG-PET/CT.

scientific article published on 23 March 2017

Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation

Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

scientific article

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production

scientific article published in November 2017

LSD1 Makes Fat Colorful

scientific article published in November 2016

Large-scale purification of oligonucleotides by extraction and precipitation with butanole

scientific article published on 01 March 2005

Lipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function

scientific article published on 25 May 2017

Liver ubiquitome uncovers nutrient-stress-mediated trafficking and secretion of complement C3

scientific article published on 13 October 2016

Longitudinal evaluation of hepatic lipid deposition and composition in ob/ob and ob/+ control mice

scientific article

Malfunctioning of adipocytes in obesity is linked to quantitative surfaceome changes

scientific article published in July 2013

Maternal high-fat diet in mice programs emotional behavior in adulthood

scientific article published on 23 May 2012

Maternal overnutrition leads to cognitive and neurochemical abnormalities in C57BL/6 mice.

scientific article published in February 2018

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs.

scientific article published on 6 May 2019

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

scientific article published on 16 September 2007

Michael John Owen Wakelam 1955-2020

scientific article published on 01 June 2020

Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice

scientific article published in February 2016

New horizons for future research - Critical issues to consider for maximizing research excellence and impact.

scientific article published on 12 May 2018

Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources-The MediHealth Project

scientific article published on 6 May 2018

Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis

scientific article published on 13 December 2021

Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase

scientific article published in January 2018

Phenotypic Analysis of BAT versus WAT Differentiation

scientific article

Plasma concentration of intestinal- and liver-FABP in neonates suffering from necrotizing enterocolitis and in healthy preterm neonates

scientific article published in October 2002

Proliferation of nutrition sensing preadipocytes upon short term HFD feeding

scientific article published on 29 September 2018

Proteomic Analysis of Human Brown Adipose Tissue Reveals Utilization of Coupled and Uncoupled Energy Expenditure Pathways

scientific article published on 15 July 2016

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier

scientific article published on 4 September 2017

Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.

scientific article published on 11 February 2015

Regulation of De Novo Adipocyte Differentiation Through Cross Talk Between Adipocytes and Preadipocytes

scientific article published on 4 September 2015

Regulation of adaptive behaviour during fasting by hypothalamic Foxa2.

scientific article

Regulation of adipocyte formation by GLP-1/GLP-1R signaling

scientific article published on 29 December 2011

Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels

scientific article (publication date: December 2003)

Role of Foxa-2 in adipocyte metabolism and differentiation

scientific article

SRF and MKL1 Independently Inhibit Brown Adipogenesis

scientific article published on 26 January 2017

Secretin activates brown fat and induces satiation

scientific article published in 2021

Short-term feeding of a ketogenic diet induces more severe hepatic insulin resistance than an obesogenic high-fat diet

scientific article published on 08 August 2018

Synthetic inositol phosphoglycans related to GPI lack insulin-mimetic activity

scientific article published on November 2010

TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling

scientific article

TaqIA polymorphism in dopamine D2 receptor gene complicates weight maintenance in younger obese patients

scientific article published on 25 April 2012

The A-allele of the common FTO gene variant rs9939609 complicates weight maintenance in severe obese patients ⬇️

scientific article published on February 7, 2012

The dual role of BMP4 in adipogenesis and metabolism

scientific article published on 6 February 2017

The origin and definition of brite versus white and classical brown adipocytes

scientific article

Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans ⬇️

scientific article published on March 25, 2011

Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue

scientific journal article

Transcriptional regulation of adipocyte formation by the liver receptor homologue 1 (Lrh1)-Small hetero-dimerization partner (Shp) network

scientific article published on 16 March 2013

Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition

article

Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice

scientific article published on 11 August 2016

Weight Loss Improves Endothelial Function Independently of ADMA Reduction in Severe Obesity ⬇️

scientific article published on March 1, 2011

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

scientific article published on 28 October 2020

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