List of works - Miguel Perez-Aso

Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements

scientific article

Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation

scientific article published on July 2013

Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.

scientific article

Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.

scientific article

Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balance

scientific article published on 08 June 2013

Adenosine A2A receptor and TNF-α regulate the circadian machinery of the human monocytic THP-1 cells.

scientific article published on February 2013

Adenosine A2A receptor plays an important role in radiation-induced dermal injury

scientific article

Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.

scientific article published on 5 September 2016

Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

scientific article

Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.

scientific article published on December 2014

Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targeting

scientific article

Different β-adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways: implications in the relaxant response of rat conductance and resistance vessels.

scientific article published on May 2013

Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.

scientific article

Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.

scientific article published on December 2013

Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation

scientific article

Striae reconstructed, a full thickness skin model that recapitulates the pathology behind stretch marks

scientific article published on 01 June 2019

The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.

scientific article published on 16 November 2017

α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries.

scientific article

β-Adrenoceptors differentially regulate vascular tone and angiogenesis of rat aorta via ERK1/2 and p38.

scientific article

List of works by Miguel Perez-Aso

Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements

Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation

Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.

Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.

Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balance

Adenosine A2A receptor and TNF-α regulate the circadian machinery of the human monocytic THP-1 cells.

Adenosine A2A receptor plays an important role in radiation-induced dermal injury

Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.

Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.

Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targeting

Different β-adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways: implications in the relaxant response of rat conductance and resistance vessels.

Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.

Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.

Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation

Striae reconstructed, a full thickness skin model that recapitulates the pathology behind stretch marks

The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.

α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries.

β-Adrenoceptors differentially regulate vascular tone and angiogenesis of rat aorta via ERK1/2 and p38.