List of works - Robert M. Tanguay

A minor alternative transcript of the fumarylacetoacetate hydrolase gene produces a protein despite being likely subjected to nonsense-mediated mRNA decay

scientific article

Age Dependent Dysfunction of Mitochondrial and ROS Metabolism Induced by Mitonuclear Mismatch

article

Age-dependent posttranslational modifications of voltage-dependent anion channel 1.

scientific article

Analysis and phylogeny of small heat shock proteins from marine viruses and their cyanobacteria host

scientific article published in 2013

Analysis of insect nuclear small heat shock proteins and interacting proteins

scientific article published on 04 September 2020

Annexin A1 is regulated by domains cross-talk through post-translational phosphorylation and SUMOYlation

scientific article published on 29 May 2013

Annexin A2 is SUMOylated on its N-terminal domain: regulation by insulin

scientific article

Antibodies against heat shock proteins in environmental stresses and diseases: friend or foe?

scientific article

Association of HSP70 and genotoxic damage in lymphocytes of workers exposed to coke-oven emission

scientific article (publication date: October 2002)

Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers

scientific article

Association of hsp70-2 and hsp-hom gene polymorphisms with risk of acute high-altitude illness in a Chinese population

scientific article

Association of increased heat shock protein 70 levels in the lymphocyte with high risk of adverse pregnancy outcomes in early pregnancy: a nested case-control study

scientific article

Basal and inducible levels of Hsp70 in patients with acute heat illness induced during training

scientific article published on January 2003

Biochemical and Clinical Aspects of Hereditary Tyrosinemia Type 1.

scientific article published in January 2017

Cellular accumulation of heat shock protein (Hsp) 72i in fetuses of trained rats

scientific article

Changes in Drosophila mitochondrial proteins following chaperone-mediated lifespan extension confirm a role of Hsp22 in mitochondrial UPR and reveal a mitochondrial localization for cathepsin D.

scientific article published on 27 February 2016

Circulating MicroRNAs and the occurrence of acute myocardial infarction in Chinese populations

scientific article published on 13 March 2014

Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction.

scientific article

Cytoplasmic nonsense-mediated mRNA decay for a nonsense (W262X) transcript of the gene responsible for hereditary tyrosinemia, fumarylacetoacetate hydrolase

scientific article

Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila

scientific article

Differences in the chaperone-like activities of the four main small heat shock proteins of Drosophila melanogaster

scientific article

Direct molecular detection of nucleic acids by fluorescence signal amplification.

scientific article published in September 2005

Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.

scientific article published on 24 August 2006

Drosophila melanogaster Hsp22: a mitochondrial small heat shock protein influencing the aging process

scientific article published on 16 March 2015

Drosophila melanogaster mitochondrial Hsp22: a role in resistance to oxidative stress, aging and the mitochondrial unfolding protein response

scientific article published on 09 July 2015

Drosophila small heat shock proteins: cell and organelle-specific chaperones?

scientific article

Effect of N-terminal region of nuclear Drosophila melanogaster small heat shock protein DmHsp27 on function and quaternary structure.

scientific article

Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation

scientific article published on 13 July 2011

Effects of hypoxia on stress proteins in the piglet heart at birth

scientific article

Evaluation of dichloroacetate treatment in a murine model of hereditary tyrosinemia type 1

scientific article published on 03 April 2006

Expression of heat shock proteins in myocardium of patients with atrial fibrillation

scientific article

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura

scientific article

Expression of the Hsp23 chaperone during Drosophila embryogenesis: association to distinct neural and glial lineages ⬇️

scientific article published on November 14, 2003

Ferruccio Ritossa's scientific legacy 50 years after his discovery of the heat shock response: a new view of biology, a new society, and a new journal

scientific article published on 18 January 2012

Frequency-specific association of antibodies against heat shock proteins 60 and 70 with noise-induced hearing loss in Chinese workers

scientific article

Frequent mutation reversion inversely correlates with clinical severity in a genetic liver disease, hereditary tyrosinemia

scientific article published in December 2003

Functional SNPs in HSPA1A gene predict risk of coronary heart disease

scientific article

Functional conservatism among Drosophila simulans flies experiencing different thermal regimes and mitochondrial DNA introgression.

scientific article published in December 2010

Functional interaction between human herpesvirus 6 immediate-early 2 protein and ubiquitin-conjugating enzyme 9 in the absence of sumoylation.

scientific article

Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22.

scientific article published on 29 December 2009

Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population

scientific article

Geographical and Ethnic Distribution of Mutations of the Fumarylacetoacetate Hydrolase Gene in Hereditary Tyrosinemia Type 1

scientific article published on 15 February 2015

Guidelines for the nomenclature of the human heat shock proteins

scientific article

Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently

scientific article

Heat shock proteins and aging in Drosophila melanogaster

scientific article published on October 2003

Heat shock response associated with hepatocarcinogenesis in a murine model of hereditary tyrosinemia type I.

scientific article published on 23 April 2014

Hepatic stress in hereditary tyrosinemia type 1 (HT1) activates the AKT survival pathway in the fah-/- knockout mice model

scientific article

Hereditary tyrosinemia: an endoplasmic reticulum stress disorder?

scientific article published in October 2003

Identification of circulating microRNAs during the liver neoplastic process in a murine model of hereditary tyrosinemia type 1.

scientific article published on 10 June 2016

Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase

scientific article

Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis.

scientific article published on 6 March 2018

In Vitro Structural and Functional Characterization of the Small Heat Shock Proteins (sHSP) of the Cyanophage S-ShM2 and Its Host, Synechococcus sp. WH7803

scientific article

In vitro study on role of Hsp70 expression in DNA damage of human embryonic lung cells exposed to Benzo[a]pyrene.

scientific article published in June 2004

Involvement of endoplasmic reticulum stress in hereditary tyrosinemia type I.

scientific article published on 29 November 2005

Menin is a regulator of the stress response in Drosophila melanogaster

scientific article

Mitochondria and ageing in Drosophila

scientific article published on June 2008

Mitochondrial Hsp70 and the troubles of nomenclature: leaving behind tradition to gain intuitiveness and clarity

scientific article published on 22 May 2016

Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration.

scientific article published on 3 October 2012

Molecular Aspects of the FAH Mutations Involved in HT1 Disease

scientific article published in January 2017

Molecular Pathogenesis of Liver Injury in Hereditary Tyrosinemia 1.

scientific article published in January 2017

Molecular changes associated with chronic liver damage and neoplastic lesions in a murine model of hereditary tyrosinemia type 1

scientific article published in December 2015

Mutations in the fumarylacetoacetate hydrolase gene causing hereditary tyrosinemia type I: Overview

scientific article (publication date: 1997)

Naturally occurring mitochondrial DNA haplotypes exhibit metabolic differences: insight into functional properties of mitochondria

scientific article published on 21 May 2012

No evidence of maternal cell colonization in reverted liver nodules of tyrosinemia type I patients

scientific article published in November 2004

Oligomeric structure and chaperone-like activity of Drosophila melanogaster mitochondrial small heat shock protein Hsp22 and arginine mutants in the alpha-crystallin domain

scientific article published on 7 April 2017

Oligomerization and chaperone-like activity of Drosophila melanogaster small heat shock protein DmHsp27 and three arginine mutants in the alpha-crystallin domain

scientific article published on 8 December 2016

Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner

scientific article

Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress

scientific article

Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population

scientific article

Plasma antibodies to heat shock protein 60 and heat shock protein 70 are associated with increased risk of electrocardiograph abnormalities in automobile workers exposed to noise

scientific article

Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome

scientific article

Presence of three mutations in the fumarylacetoacetate hydrolase gene in a patient with atypical symptoms of hereditary tyrosinemia type I

scientific article published on 07 February 2019

Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells

scientific article

Protection from aging by small chaperones: A trade-off with cancer?

scientific article published on June 2010

Proteomic characterization of mouse cytosolic and membrane prostate fractions: high levels of free SUMO peptides are androgen-regulated

scientific article published on 27 August 2008

Rescue from neonatal death in the murine model of hereditary tyrosinemia by glutathione monoethylester and vitamin C treatment

scientific article published on 26 November 2007

Serum and lymphocyte levels of heat shock protein 70 in aging: a study in the normal Chinese population.

scientific article

Small heat shock protein expression and functions during development ⬇️

scientific article published on March 28, 2012

Small heat shock proteins: big folding machines

scientific article

Small heat shock proteins: multifaceted proteins with important implications for life

scientific article published on 13 February 2019

Steady-state kinetics and inhibition of anaerobically purified human homogentisate 1,2-dioxygenase

scientific article published on March 2005

Stress and health Huangshan-style

scientific article

Stress at the Korean Mountains: meeting report of the 8th International Workshop on the Molecular Biology of Stress Responses ⬇️

scientific article published on October 2, 2010

Stress under the dam: meeting report of the Fourth International Workshop on the Molecular Biology of Stress Responses

scientific article

Structural and functional properties of proteins interacting with small heat shock proteins

scientific article published on 20 April 2020

The growing world of small heat shock proteins: from structure to functions

scientific article published on 31 March 2017

The level of Hsp27 in lymphocytes is negatively associated with a higher risk of lung cancer

scientific article published on 18 September 2008

The nuclear localization of Drosophila Hsp27 is dependent on a monopartite arginine-rich NLS and is uncoupled from its association to nuclear speckles

scientific article

The pathogenic human Torsin A in Drosophila activates the unfolded protein response and increases susceptibility to oxidative stress

scientific article published on 23 April 2015

The small heat-shock protein Hsp27 undergoes ERK-dependent phosphorylation and redistribution to the cytoskeleton in response to dual leucine zipper-bearing kinase expression

scientific article published in January 2010

The use of the Xenopus oocyte as a model system to analyze the expression and function of eukaryotic heat shock proteins

scientific article published on 28 March 2007

Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes.

scientific article published on 30 March 2011

Thermal sensitivity of mitochondrial metabolism in two distinct mitotypes of Drosophila simulans: evaluation of mitochondrial plasticity

scientific article published in May 2010

Thermoprotection of synaptic transmission in a Drosophila heat shock factor mutant is accompanied by increased expression of Hsp83 and DnaJ-1.

scientific article published on 04 April 2006

UVC-induced stress granules in mammalian cells

scientific article

Using lymphocyte and plasma Hsp70 as biomarkers for assessing coke oven exposure among steel workers

scientific article

Variants of HSPA1A in combination with plasma Hsp70 and anti-Hsp70 antibody levels associated with higher risk of acute coronary syndrome

scientific article published on 17 August 2011

List of works by Robert M. Tanguay

A minor alternative transcript of the fumarylacetoacetate hydrolase gene produces a protein despite being likely subjected to nonsense-mediated mRNA decay

Age Dependent Dysfunction of Mitochondrial and ROS Metabolism Induced by Mitonuclear Mismatch

Age-dependent posttranslational modifications of voltage-dependent anion channel 1.

Analysis and phylogeny of small heat shock proteins from marine viruses and their cyanobacteria host

Analysis of insect nuclear small heat shock proteins and interacting proteins

Annexin A1 is regulated by domains cross-talk through post-translational phosphorylation and SUMOYlation

Annexin A2 is SUMOylated on its N-terminal domain: regulation by insulin

Antibodies against heat shock proteins in environmental stresses and diseases: friend or foe?

Association of HSP70 and genotoxic damage in lymphocytes of workers exposed to coke-oven emission

Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers

Association of hsp70-2 and hsp-hom gene polymorphisms with risk of acute high-altitude illness in a Chinese population

Association of increased heat shock protein 70 levels in the lymphocyte with high risk of adverse pregnancy outcomes in early pregnancy: a nested case-control study

Basal and inducible levels of Hsp70 in patients with acute heat illness induced during training

Biochemical and Clinical Aspects of Hereditary Tyrosinemia Type 1.

Cellular accumulation of heat shock protein (Hsp) 72i in fetuses of trained rats

Changes in Drosophila mitochondrial proteins following chaperone-mediated lifespan extension confirm a role of Hsp22 in mitochondrial UPR and reveal a mitochondrial localization for cathepsin D.

Circulating MicroRNAs and the occurrence of acute myocardial infarction in Chinese populations

Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction.

Cytoplasmic nonsense-mediated mRNA decay for a nonsense (W262X) transcript of the gene responsible for hereditary tyrosinemia, fumarylacetoacetate hydrolase

Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila

Differences in the chaperone-like activities of the four main small heat shock proteins of Drosophila melanogaster

Direct molecular detection of nucleic acids by fluorescence signal amplification.

Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.

Drosophila melanogaster Hsp22: a mitochondrial small heat shock protein influencing the aging process

Drosophila melanogaster mitochondrial Hsp22: a role in resistance to oxidative stress, aging and the mitochondrial unfolding protein response

Drosophila small heat shock proteins: cell and organelle-specific chaperones?

Effect of N-terminal region of nuclear Drosophila melanogaster small heat shock protein DmHsp27 on function and quaternary structure.

Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation

Effects of hypoxia on stress proteins in the piglet heart at birth

Evaluation of dichloroacetate treatment in a murine model of hereditary tyrosinemia type 1

Expression of heat shock proteins in myocardium of patients with atrial fibrillation

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura

Expression of the Hsp23 chaperone during Drosophila embryogenesis: association to distinct neural and glial lineages ⬇️

Ferruccio Ritossa's scientific legacy 50 years after his discovery of the heat shock response: a new view of biology, a new society, and a new journal

Frequency-specific association of antibodies against heat shock proteins 60 and 70 with noise-induced hearing loss in Chinese workers

Frequent mutation reversion inversely correlates with clinical severity in a genetic liver disease, hereditary tyrosinemia

Functional SNPs in HSPA1A gene predict risk of coronary heart disease

Functional conservatism among Drosophila simulans flies experiencing different thermal regimes and mitochondrial DNA introgression.

Functional interaction between human herpesvirus 6 immediate-early 2 protein and ubiquitin-conjugating enzyme 9 in the absence of sumoylation.

Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22.

Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population

Geographical and Ethnic Distribution of Mutations of the Fumarylacetoacetate Hydrolase Gene in Hereditary Tyrosinemia Type 1

Guidelines for the nomenclature of the human heat shock proteins

Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently

Heat shock proteins and aging in Drosophila melanogaster

Heat shock response associated with hepatocarcinogenesis in a murine model of hereditary tyrosinemia type I.

Hepatic stress in hereditary tyrosinemia type 1 (HT1) activates the AKT survival pathway in the fah-/- knockout mice model

Hereditary tyrosinemia: an endoplasmic reticulum stress disorder?

Identification of circulating microRNAs during the liver neoplastic process in a murine model of hereditary tyrosinemia type 1.

Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase

Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis.

In Vitro Structural and Functional Characterization of the Small Heat Shock Proteins (sHSP) of the Cyanophage S-ShM2 and Its Host, Synechococcus sp. WH7803

In vitro study on role of Hsp70 expression in DNA damage of human embryonic lung cells exposed to Benzo[a]pyrene.

Involvement of endoplasmic reticulum stress in hereditary tyrosinemia type I.

Menin is a regulator of the stress response in Drosophila melanogaster

Mitochondria and ageing in Drosophila

Mitochondrial Hsp70 and the troubles of nomenclature: leaving behind tradition to gain intuitiveness and clarity

Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration.

Molecular Aspects of the FAH Mutations Involved in HT1 Disease

Molecular Pathogenesis of Liver Injury in Hereditary Tyrosinemia 1.

Molecular changes associated with chronic liver damage and neoplastic lesions in a murine model of hereditary tyrosinemia type 1

Mutations in the fumarylacetoacetate hydrolase gene causing hereditary tyrosinemia type I: Overview

Naturally occurring mitochondrial DNA haplotypes exhibit metabolic differences: insight into functional properties of mitochondria

No evidence of maternal cell colonization in reverted liver nodules of tyrosinemia type I patients

Oligomeric structure and chaperone-like activity of Drosophila melanogaster mitochondrial small heat shock protein Hsp22 and arginine mutants in the alpha-crystallin domain

Oligomerization and chaperone-like activity of Drosophila melanogaster small heat shock protein DmHsp27 and three arginine mutants in the alpha-crystallin domain

Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner

Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress

Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population

Plasma antibodies to heat shock protein 60 and heat shock protein 70 are associated with increased risk of electrocardiograph abnormalities in automobile workers exposed to noise

Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome

Presence of three mutations in the fumarylacetoacetate hydrolase gene in a patient with atypical symptoms of hereditary tyrosinemia type I

Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells

Protection from aging by small chaperones: A trade-off with cancer?

Proteomic characterization of mouse cytosolic and membrane prostate fractions: high levels of free SUMO peptides are androgen-regulated

Rescue from neonatal death in the murine model of hereditary tyrosinemia by glutathione monoethylester and vitamin C treatment

Serum and lymphocyte levels of heat shock protein 70 in aging: a study in the normal Chinese population.

Small heat shock protein expression and functions during development ⬇️

Small heat shock proteins: big folding machines