List of works - Akul Y Mehta

Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.

scientific article

Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors

scientific article

Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.

scientific article published on 9 January 2016

An update on recent patents on thrombin inhibitors (2010 - 2013)

scientific article

Antigenic Pressure on H3N2 Influenza Virus Drift Strains Imposes Constraints on Binding to Sialylated Receptors but Not Phosphorylated Glycans

scientific article published on 29 October 2019

Chemoenzymatically prepared heparan sulfate containing rare 2-O-sulfonated glucuronic acid residues.

scientific article published on 17 March 2015

Comparative analysis of INLIGHT™-labeled enzymatically depolymerized heparin by reverse-phase chromatography and high-performance mass spectrometry

scientific article published on 25 November 2016

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO Biochemistry

scientific article

Designing Allosteric Regulators of Thrombin. Exosite 2 Features Multiple Subsites That Can Be Targeted by Sulfated Small Molecules for Inducing Inhibition

scientific article (publication date: 27 June 2013)

GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays

scientific article published on 01 September 2019

GlyGen: Computational and Informatics Resources for Glycoscience

scientific article published on 01 January 2020

Interaction of Thrombin with Sucrose Octasulfate

scientific article

Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.

scientific article

Rational design of potent, small, synthetic allosteric inhibitors of thrombin

scientific article

Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2.

scientific article

Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa

scientific article

Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects

scientific article (publication date: 10 April 2014)

Tools for generating and analyzing glycan microarray data

scientific article published on 10 September 2020

List of works by Akul Y Mehta

Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.

Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors

Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.

An update on recent patents on thrombin inhibitors (2010 - 2013)

Antigenic Pressure on H3N2 Influenza Virus Drift Strains Imposes Constraints on Binding to Sialylated Receptors but Not Phosphorylated Glycans

Chemoenzymatically prepared heparan sulfate containing rare 2-O-sulfonated glucuronic acid residues.

Comparative analysis of INLIGHT™-labeled enzymatically depolymerized heparin by reverse-phase chromatography and high-performance mass spectrometry

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO Biochemistry

Designing Allosteric Regulators of Thrombin. Exosite 2 Features Multiple Subsites That Can Be Targeted by Sulfated Small Molecules for Inducing Inhibition

GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays

GlyGen: Computational and Informatics Resources for Glycoscience

Interaction of Thrombin with Sucrose Octasulfate

Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.

Rational design of potent, small, synthetic allosteric inhibitors of thrombin

Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2.

Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa

Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects

Tools for generating and analyzing glycan microarray data