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List of works by Miguel A Pineda

Apigenin C-glycosides of Microcos paniculata protects lipopolysaccharide induced apoptosis and inflammation in acute lung injury through TLR4 signaling pathway

scientific article published on 08 June 2018

Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62.

scientific article

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

scientific article

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus

scientific article

ES-62 protects against collagen-induced arthritis by resetting interleukin-22 toward resolution of inflammation in the joints

scientific article published on June 2014

ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae.

scientific article published on 23 March 2014

From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home.

scientific article

From the worm to the pill, the parasitic worm product ES-62 raises new horizons in the treatment of rheumatoid arthritis.

scientific article published on April 2015

Interactions of human galectins with Trypanosoma cruzi: binding profile correlate with genetic clustering of lineages

scientific article published on 28 September 2014

Lack of Galectin-3 Prevents Cardiac Fibrosis and Effective Immune Responses in a Murine Model of Trypanosoma cruzi Infection.

scientific article published on 24 March 2015

Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis.

scientific article published on July 2014

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis.

scientific article

Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints.

scientific article published on March 2014

Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation.

scientific article published on 30 March 2015

Reply to Novaes et al

scientific article published on 13 October 2015

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts

scientific article published on 08 November 2021

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ.

scientific article published on 21 November 2016

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17-producing cellular network at multiple sites

scientific article published on 01 October 2012

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

article

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

scientific article published on 12 March 2020

The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice

scientific article published on April 2015

The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis.

scientific article published on January 2014

Trypanosoma cruzi cleaves galectin-3 N-terminal domain to suppress its innate microbicidal activity

scientific article published on 27 October 2019