List of works - Mark C de Gooijer

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

scientific article

ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy

scientific article published on 19 March 2014

Buparlisib is a brain penetrable pan-PI3K inhibitor

scientific article published on 17 July 2018

Combined therapy of AXL and HDAC inhibition reverses mesenchymal transition in diffuse intrinsic pontine glioma

scientific article published on 12 March 2020

Determination of NVP-BEZ235, a dual PI3K and mTOR inhibitor, in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography with fluorescence detection

scientific article published on 08 June 2012

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

scientific article

HG-52MELK INHIBITION AS A POTENTIAL TREATMENT FOR DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article published on 30 May 2016

Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness.

scientific article

MELK Inhibition in Diffuse Intrinsic Pontine Glioma

scientific article published on 30 July 2018

Overcoming the blood-brain tumor barrier for effective glioblastoma treatment

scientific article published on 06 March 2015

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.

scientific article

PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models.

scientific article published on 23 August 2016

Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.

scientific article

The G2 checkpoint-a node-based molecular switch

scientific article published on 4 March 2017

The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors

scientific article published on 16 September 2017

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

scientific article published on 09 March 2022

List of works by Mark C de Gooijer

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy

Buparlisib is a brain penetrable pan-PI3K inhibitor

Combined therapy of AXL and HDAC inhibition reverses mesenchymal transition in diffuse intrinsic pontine glioma

Determination of NVP-BEZ235, a dual PI3K and mTOR inhibitor, in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography with fluorescence detection

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

HG-52MELK INHIBITION AS A POTENTIAL TREATMENT FOR DIFFUSE INTRINSIC PONTINE GLIOMA.

Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness.

MELK Inhibition in Diffuse Intrinsic Pontine Glioma

Overcoming the blood-brain tumor barrier for effective glioblastoma treatment

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.

PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models.

Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.

The G2 checkpoint-a node-based molecular switch

The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants