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List of works by Jan van Riggelen

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

scholarly article

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma

scientific article published on 10 August 2017

Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells

scientific article

Ectopic expression of nonliganded retinoic acid receptor beta abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells

scientific article

High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation.

scientific article published on 8 May 2012

Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation

Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells.

scientific article

Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction ⬇️

scientific article published on October 3, 2011

MYC as a regulator of ribosome biogenesis and protein synthesis

scientific article published on April 2010

MYC-Master Regulator of the Cancer Epigenome and Transcriptome

scientific article

Myc and a Cdk2 senescence switch.

scientific article published in January 2010

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.

scholarly article

TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas

scientific article published in December 2010

Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition

The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance

scientific article

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia

scientific article

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