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List of works by Michael Kiehntopf

A Friday afternoon case of apparent anti-glomerular basement nephritis

scientific article (publication date: August 2006)

A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans

scientific article published on 20 October 2011

A homemade MLPA assay detects known CTNS mutations and identifies a novel deletion in a previously unresolved cystinosis family

scientific article published on 24 December 2011

A microfluidically perfused three dimensional human liver model

scientific article published on 25 August 2015

Alpha-fetoprotein and its value for predicting pregnancy outcomes - a re-evaluation

scientific article published on July 2015

Analysis of single blood cells for CSF diagnostics via a combination of fluorescence staining and micro-Raman spectroscopy

scientific article published on 28 May 2008

Analysis of the CTNS gene in patients of German and Swiss origin with nephropathic cystinosis

scientific article (publication date: September 2002)

Annotating German Clinical Documents for De-Identification

scientific article published on 01 August 2019

Antioxidants prevent health-promoting effects of physical exercise in humans

scientific article

Application of the EMIT 2000 Tacrolimus assay on the Abbott Architect c8000 high volume clinical chemistry analyzer

scientific article published on 21 July 2006

Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group

scientific article

Association of proteome and metabolome signatures with severity in patients with community-acquired pneumonia

scientific article published on 30 December 2019

Automated monitoring of C2 and C0 blood levels of mycophenolic acid and cyclosporine on the Abbott Architect c8000.

scientific article published on 5 July 2007

Biobanking and international interoperability: samples ⬇️

scientific article published on July 15, 2011

Biomarker candidates for the detection of an infectious etiology of febrile neutropenia

scientific article published on 15 August 2015

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

scientific article

C-Terminal Alpha-1 Antitrypsin Peptide: A New Sepsis Biomarker with Immunomodulatory Function

scientific article published on 13 June 2016

CAAP48, a New Sepsis Biomarker, Induces Hepatic Dysfunction in an Liver-on-Chip Model

CDA-Compliant Section Annotation of German-Language Discharge Summaries: Guideline Development, Annotation Campaign, Section Classification

article

Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages

scientific article published on 30 November 2018

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction

article published in 2021

Clinical and endocrine correlates of circulating sclerostin levels in patients with type 1 diabetes mellitus

scientific article published on 12 December 2013

Clinical significance and diagnostic usefulness of serologic markers for improvement of outcome of tonsillectomy in adults with chronic tonsillitis

scientific article published on July 2013

Comparison of six D-dimer assays for the detection of clinically suspected deep venous thrombosis of the lower extremities

scientific article published on March 2009

Comparison of the ecarin chromogenic assay and different aPTT assays for the measurement of argatroban concentrations in plasma from healthy individuals and from coagulation factor deficient patients

scientific article published on 22 April 2008

Consequences of a high phosphorus intake on mineral metabolism and bone remodeling in dependence of calcium intake in healthy subjects - a randomized placebo-controlled human intervention study

scientific article

Consumption of echium oil increases EPA and DPA in blood fractions more efficiently compared to linseed oil in humans

scientific article published on 18 February 2016

Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.

scientific article

Culture independent Raman spectroscopic identification of urinary tract infection pathogens: a proof of principle study

scientific article published on 24 September 2013

Decrease in circulating plasmacytoid dendritic cells during short-term systemic normobaric hypoxia

scientific article

Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice

scientific article

Detection of thiopurine methyltransferase activity in lysed red blood cells by means of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS) ⬇️

scientific article published on February 26, 2011

Dietary echium oil increases long-chain n-3 PUFAs, including docosapentaenoic acid, in blood fractions and alters biochemical markers for cardiovascular disease independently of age, sex, and metabolic syndrome

scientific article

Differentiation ofCampylobacterSpecies by Surface-Enhanced Laser Desorption/Ionization–Time-of-Flight Mass Spectrometry ⬇️

scientific article published on April 27, 2011

Direct analysis of clinical relevant single bacterial cells from cerebrospinal fluid during bacterial meningitis by means of micro-Raman spectroscopy

scientific article published on 01 February 2009

Dynamics of cytokines, immune cell counts and disease severity in patients with community-acquired pneumonia - Unravelling potential causal relationships

scientific article published on 03 September 2020

Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis ⬇️

scientific article published on June 13, 2012

Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial

scientific article published on 18 July 2016

Effect of calcium phosphate and vitamin D₃ supplementation on bone remodelling and metabolism of calcium, phosphorus, magnesium and iron

scientific article published on 17 January 2014

Effect of the Method for Creatinine Measurement

scientific article published on April 2017

Effects of early- and late-gestational maternal stress and synthetic glucocorticoid on development of the fetal hypothalamus–pituitary–adrenal axis in sheep ⬇️

scientific article published on June 4, 2012

End-stage renal failure as manifestation of adolescent cystinosis

scientific article published on 7 February 2004

Evaluation of a straightforward and rapid method for the therapeutic drug monitoring of digitoxin by LC-MS/MS ⬇️

scientific article published on August 16, 2013

Evaluation of two different albumin depletion strategies for improved analysis of human CSF by SELDI-TOF-MS.

scientific article

Fast differentiation of SIRS and sepsis from blood plasma of ICU patients using Raman spectroscopy

scientific article published on 17 March 2014

Functional mutation analysis provides evidence for a role of REEP1 in lipid droplet biology

scientific article published on 5 March 2014

Gene Polymorphisms in the Heme Degradation Pathway and Outcome of Severe Human Sepsis

scientific article published on 01 November 2012

Gene for integrin-associated protein (IAP, CD47): physical mapping, genomic structure, and expression studies in skeletal muscle

scientific article published on 01 January 2002

Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia

scientific article published on 13 March 2012

Histidine degradation via an aminotransferase increases the nutritional flexibility of Candida glabrata

scientific article published on 11 April 2014

Identification of nuclear localisation sequences in spastin (SPG4) using a novel Tetra-GFP reporter system

scientific article

Imatinib mesylate attenuates fibrosis in coxsackievirus b3-induced chronic myocarditis

scientific article published on 7 March 2008

Imbalance of von Willebrand factor and its cleaving protease ADAMTS13 during systemic inflammation superimposed on advanced cirrhosis

scientific article published on 3 September 2014

Immature platelet fraction as marker for platelet recovery after stem cell transplantation in children ⬇️

scientific article published on March 27, 2012

Immediate diagnosis of ventriculits: evaluation of parameters independent of microbiological culture

scientific article published on 19 July 2011

In patients with aortic stenosis increased flow-mediated dilation is independently associated with higher peak jet velocity and lower asymmetric dimethylarginine levels ⬇️

scientific article published on April 12, 2011

Influence of direct thrombin inhibitor argatroban on coagulation assays in healthy individuals, patients under oral anticoagulation therapy and patients with liver dysfunction

scientific article published in June 2008

Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth

scientific article

Integrated analysis of the cerebrospinal fluid peptidome and proteome

scientific article published on 04 December 2007

Intensive insulin therapy and pentastarch resuscitation in severe sepsis

scientific article

Introduction of BD Vacutainer® Barricor™ tubes in clinical biobanking and application of amino acid and cytokine quality indicators to Barricor plasma

scientific article published on 24 January 2022

Is successful electroconvulsive therapy related to stimulation of the vagal system?

scientific article published on 3 March 2010

LacaScore: a novel plasma sample quality control tool based on ascorbic acid and lactic acid levels

scientific article published on 27 April 2016

Limited comparability of creatinine assays in patients with liver cirrhosis and their impact on the MELD score

scientific article published on 14 April 2017

Lipid metabolic signatures deviate in sepsis survivors compared to non-survivors

scientific article published on 21 November 2020

Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study ⬇️

scientific article published on August 1, 2013

Mass spectometry-based protein patterns in the diagnosis of sepsis/systemic inflammatory response syndrome

scientific article published on December 2011

Measurement of piperacillin plasma concentrations in cancer patients with suspected infection

scientific article published on 17 May 2017

Metabolism, metabolome, and metabolomics in intensive care: is it time to move beyond monitoring of glucose and lactate?

scientific article published on 01 May 2013

Metabolite Profiles in Sepsis: Developing Prognostic Tools Based on the Type of Infection

scientific article published on 19 April 2016

Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma

scientific article published on 22 September 2021

Microvascular tissue perfusion is impaired in acutely decompensated heart failure and improves following standard treatment

scientific article published on 04 May 2011

Milk phospholipid and plant sterol-dependent modulation of plasma lipids in healthy volunteers ⬇️

scientific article published on July 27, 2012

Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice

Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model

scientific article published on 23 February 2016

NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity

scientific article published in December 2008

Optimized Identification of Advanced Chronic Kidney Disease and Absence of Kidney Disease by Combining Different Electronic Health Data Resources and by Applying Machine Learning Strategies

scientific article published on 12 September 2020

Outcome-based profiling of astrocytic tumours identifies prognostic gene expression signatures which link molecular and morphology-based pathology.

scientific article published in November 2006

PROGRESS - prospective observational study on hospitalized community acquired pneumonia

scientific article published on 28 July 2016

Postprandial effects of calcium phosphate supplementation on plasma concentration-double-blind, placebo-controlled cross-over human study ⬇️

scientific article published on March 8, 2013

Preoperative serum pattern analysis to predict the outcome of tonsillectomy in adults with chronic tonsillitis

scientific article published on 11 May 2014

Preservation of Cell Structure, Metabolism, and Biotransformation Activity of Liver-On-Chip Organ Models by Hypothermic Storage

scientific article published on 27 September 2017

Prognostic impact of pretherapeutic laboratory values in head and neck cancer patients

scientific article published on 25 September 2012

Prognostic impact of standard laboratory values on outcome in patients with sudden sensorineural hearing loss

scientific article

Putting science to work: novel diagnostic strategies in laboratory medicine

scientific article published on 01 January 2006

Quality Assessment of the Preanalytical Workflow in Liquid Biobanking: Taurine as a Serum-Specific Quality Indicator for Preanalytical Process Variations

scientific article published on 24 July 2019

Randomized placebo-controlled intervention with n-3 LC-PUFA-supplemented yoghurt: effects on circulating eicosanoids and cardiovascular risk factors

scientific article published on 28 December 2012

Rapid generation of detailed loss of heterozygosity profiles for routine diagnosis of gliomas.

scientific article

Red blood cell distribution width as useful tool to predict long-term mortality in patients with chronic heart failure

scientific article published on 10 September 2011

Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia

scientific article

Results of comprehensive geriatric assessment effect survival in patients with malignant lymphoma

scientific article

Searching biomarker candidates in serum using multidimensional native chromatography. II Method evaluation with Alport syndrome and severe inflammation

scientific article

Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia - results from the prospective observational PROGRESS study

scientific article published on 04 April 2019

Shades of yellow: monitoring nutritional needs and hepatobiliary function in the critically ill

article by Michael Bauer & Michael Kiehntopf published July 2014 in Hepatology

Simultaneous quantification of nine antimicrobials by LC-MS/MS for therapeutic drug monitoring in critically ill patients

scientific article published on 01 February 2019

Standard PREanalytical Code version 3.0.

scientific article published on 29 January 2018

Star-shaped drug carriers for doxorubicin with POEGMA and POEtOxMA brush-like shells: a structural, physical, and biological comparison

scientific article published on 5 July 2013

Stress-induced decrease of uterine blood flow in sheep is mediated by alpha 1-adrenergic receptors

scientific article published on 28 June 2016

Supplementation of a dairy drink enriched with milk phospholipids in patients with atopic dermatitis - a double-blind, placebo-controlled, randomized, cross-over study

scientific article published on 29 January 2014

Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates.

scientific article

Targeted metabolomics for discrimination of systemic inflammatory disorders in critically ill patients

scientific article

The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults

The importance of intraoperative selenium blood levels on organ dysfunction in patients undergoing off-pump cardiac surgery: a randomised controlled trial

scientific article

Toward a spectroscopic hemogram: Raman spectroscopic differentiation of the two most abundant leukocytes from peripheral blood

scientific article published on 8 June 2012

Toward culture-free Raman spectroscopic identification of pathogens in ascitic fluid

scientific article published on 30 December 2014

Uncontrolled clinical study of the efficacy of ambulant fasting in patients with osteoarthritis

scientific article published on 12 March 2010

Use of SELDI-TOF mass spectrometry for identification of new biomarkers: potential and limitations

scientific article

ZNF804A and cortical structure in schizophrenia: in vivo and postmortem studies

scientific article published on 27 September 2013

[Prevalence of polyglandular autoimmune syndrome in patients with diabetes mellitus type 1]

scientific article published on 01 March 2009

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