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List of works by Elisa Vigna

"Active" cancer immunotherapy by anti-Met antibody gene transfer

scientific article

A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis ⬇️

scientific article published on December 1, 1992

Anti-Differentiation Effect of Oncogenic Met Receptor in Terminally-Differentiated Myotubes

scientific article published on 12 February 2015

CD44v6 as innovative sarcoma target for CAR-redirected CIK cells.

scientific article published on 15 February 2018

CSPG4-specific CAR.CIK lymphocytes as a novel therapy for the treatment of multiple soft tissue sarcoma histotypes

scientific article published on 08 September 2020

Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib.

scientific article published on 25 February 2016

Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody.

scientific article published on 28 March 2016

Identification of Myocardial and Vascular Precursor Cells in Human and Mouse Epicardium

scientific article published on 18 October 2007

Inhibition of ligand-independent constitutive activation of the Met oncogenic receptor by the engineered chemically-modified antibody DN30.

scientific article

MET overexpression turns human primary osteoblasts into osteosarcomas.

scientific article published on May 2006

MET/HGF Co-Targeting in Pancreatic Cancer: A Tool to Provide Insight into the Tumor/Stroma Crosstalk

scientific article published on 07 December 2018

MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma

scientific article published on 18 September 2013

Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours

scientific article published on 06 February 2019

Monovalency unleashes the full therapeutic potential of the DN-30 anti-Met antibody

scientific article

Quiescent neuronal progenitors are activated in the juvenile guinea pig lateral striatum and give rise to transient neurons

scientific article published in November 2014

Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody

scientific article published on 30 June 2016

T cell receptor (TCR) gene transfer with lentiviral vectors allows efficient redirection of tumor specificity in naive and memory T cells without prior stimulation of endogenous TCR.

scientific article

Targeted therapy by gene transfer of a monovalent antibody fragment against the Met oncogenic receptor.

scientific article published on 7 September 2013

Targeting the MET oncogene by concomitant inhibition of receptor and ligand via an antibody-"decoy" strategy

scientific article published on 10 May 2018

Targeting the oncogenic Met receptor by antibodies and gene therapy

scientific article published on 02 June 2014

The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation

scientific article published on 20 July 2009

The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation

scientific article published on April 1991

Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind MET.

scientific article

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