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List of works by Eleftheria Maratos-Flier

A guide to analysis of mouse energy metabolism

scientific article published on 28 December 2011

A high-fat, ketogenic diet induces a unique metabolic state in mice

scientific article published on 13 February 2007

A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss

scientific article published on 08 September 2009

Ablation of the hypothalamic neuropeptide melanin concentrating hormone is associated with behavioral abnormalities that reflect impaired olfactory integration

scientific article published on 6 June 2011

Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet

scientific article published on 10 July 2015

Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice ⬇️

scientific article published on March 27, 2013

Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice

scientific article

Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice

scientific article published on 29 April 2015

Cerebrospinal fluid ghrelin is negatively associated with body mass index

scientific article published in June 2003

Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain

scientific article

Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice

scientific article published in November 2004

Combined Neural Inactivation of Suppressor of Cytokine Signaling-3 and Protein-Tyrosine Phosphatase-1B Reveals Additive, Synergistic, and Factor-Specific Roles in the Regulation of Body Energy Balance ⬇️

scientific article published on September 28, 2010

Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet.

scientific article published on 8 March 2018

Dietary fatty acids differentially regulate production of TNF-alpha and IL-10 by murine 3T3-L1 adipocytes

scientific article published on 28 February 2008

Dysregulation of the mesolimbic dopamine system and reward in MCH-/- mice

scientific article

Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis

scientific article

Estradiol-induced anorexia is independent of leptin and melanin-concentrating hormone

scientific article

Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions

scientific article published on 20 June 2006

Expression of melanin-concentrating hormone receptor 2 protects against diet-induced obesity in male mice

scientific article published on 20 December 2013

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

scientific article published on February 2012

Fatty liver and FGF21 physiology

scientific article published on 23 May 2017

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas

scientific article (publication date: 2016)

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury

scientific article published on 19 August 2017

Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo

scientific article published on 24 February 2014

Fibroblast growth factor 21 has no direct role in regulating fertility in female mice

scientific article published on 18 May 2016

Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis.

scientific article

Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

scientific article

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

scientific article

Fructose ingestion acutely stimulates circulating FGF21 levels in humans

scientific article

Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease

scientific article published on 5 May 2010

Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo ⬇️

scientific article published on June 28, 2011

LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin

scientific article published on December 2004

Lasker lauds leptin

scientific article

Leptin exacerbates sepsis-mediated morbidity and mortality

scientific article published on 02 June 2010

Leptin regulation of the mesoaccumbens dopamine pathway.

scientific article published on September 2006

Leptin's Physiologic Role: Does the Emperor of Energy Balance Have No Clothes?

scientific article

MCH-/- mice are resistant to aging-associated increases in body weight and insulin resistance.

scientific article published in February 2006

Melanin concentrating hormone is a novel regulator of islet function and growth

scientific article published in February 2007

Melanin-concentrating hormone activates signaling pathways in 3T3-L1 adipocytes

scientific article

Melanin-concentrating hormone as a mediator of intestinal inflammation.

scholarly article

Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype

scientific article published on August 2003

Melanin-concentrating hormone is necessary for olanzapine-inhibited locomotor activity in male mice

scientific article published on 3 June 2015

Melanin-concentrating hormone neurons release glutamate for feedforward inhibition of the lateral septum.

scientific article published in February 2015

Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways

scientific article

Melanin-concentrating hormone receptor mutations and human obesity: functional analysis

scientific article

Melanin-concentrating hormone: from fish skin to skinny mammals

scientific article

Metabolic disease puts up a fight: microbes, metabolism and medications

scientific article

Methionine and choline regulate the metabolic phenotype of a ketogenic diet

scientific article published on 8 July 2013

Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms.

scientific article published on 24 February 2005

Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

scientific article

More than satiety: central serotonin signaling and glucose homeostasis

scientific article published on November 2007

NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting

scientific article

NPY and MC4R Signaling Regulate Thyroid Hormone Levels during Fasting through Both Central and Peripheral Pathways ⬇️

scientific article published on November 17, 2011

Neurochemical characterization of neurons expressing melanin‐concentrating hormone receptor 1 in the mouse hypothalamus ⬇️

scientific article published on July 1, 2013

Neuropeptides, including neuropeptide Y and melanocortins, mediate lipolysis in murine adipocytes

scientific article

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State ⬇️

scientific article published on August 3, 2010

Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal

scientific article published on April 2014

PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis

scientific article

Polymerase I and Transcript Release Factor Regulates Lipolysis via a Phosphorylation-Dependent Mechanism ⬇️

scientific article published on January 31, 2011

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice ⬇️

scientific article published on April 1, 2011

Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.

scientific article published on 09 April 2009

Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function

scientific article

Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice ⬇️

scientific article published on December 27, 2011

Responsiveness to peripherally administered melanocortins in lean and obese mice

scientific article published on January 2004

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

scientific journal article

Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight

scientific article published on 31 July 2008

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

scientific article

Serum ghrelin levels in response to glucose load in obese subjects post-gastric bypass surgery.

scientific article published in August 2003

Short-Term Exenatide Treatment Leads to Significant Weight Loss in a Subset of Obese Women Without Diabetes ⬇️

scientific article published on October 31, 2011

Short-term resistance to diet-induced obesity in A/J mice is not associated with regulation of hypothalamic neuropeptides

scientific article

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals

scientific article published on 16 August 2007

Stress heats up the adipocyte ⬇️

scientific article published on January 1, 2013

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

scientific article

The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans.

scientific article published on 4 September 2017

The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance.

scientific article

The long reach of leptin

scientific article published in June 2008

The stomach speaks--ghrelin and weight regulation

scientific article published in May 2002

Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner

scientific article

Transcriptional control of adipose lipid handling by IRF4

scientific article

Two paths diverge in the brain: melanin-concentrating hormone controls hepatic and adipose metabolism

scientific article

Understanding the Physiology of FGF21.

scientific article

Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice

scientific article published on 24 June 2008

What fuels fat

scientific article published on 01 September 2007

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