List of works - Angeliki Chroni

A possible structural basis behind the pathogenic role of apolipoprotein E hereditary mutations associated with lipoprotein glomerulopathy.

scientific article published on 23 October 2013

A simple approach for human recombinant apolipoprotein E4 expression and purification.

scientific article published on 25 June 2011

Allele-dependent thermodynamic and structural perturbations in ApoE variants associated with the correction of dyslipidemia and formation of spherical ApoE-containing HDL particles.

scientific article published on 23 November 2012

Amyloid-peptide β 42 enhances the oligomerization and neurotoxicity of apoE4: the C-terminal residues Leu279, Lys282 and Gln284 modulate the structural and functional properties of apoE4

scientific article published on 24 October 2018

An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines ⬇️

scientific article published on March 14, 2012

Antisense oligonucleotides, microRNAs, and antibodies.

scientific article published in January 2015

ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and Aβ production independently of their cholesterol efflux capacity

scientific article published on 31 May 2018

Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia ⬇️

scientific article published on January 1, 2011

Carboxyl Terminus of Apolipoprotein A-I (ApoA-I) Is Necessary for the Transport of Lipid-free ApoA-I but Not Prelipidated ApoA-I Particles through Aortic Endothelial Cells ⬇️

scientific article published on January 5, 2011

Characterization of antioxidant/anti-inflammatory properties and apoA-I-containing subpopulations of HDL from family subjects with monogenic low HDL disorders ⬇️

scientific article published on March 21, 2011

Cholesterol efflux and reverse cholesterol transport

scientific article

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

scientific article

Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages

scientific article published on 21 November 2018

Domains of apoE4 required for the biogenesis of apoE-containing HDL.

scientific article

Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux.

scientific article

Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells.

scientific article published on 5 July 2017

HDL biogenesis, remodeling, and catabolism.

scientific article

HDL dysfunction caused by mutations in apoA-I and other genes that are critical for HDL biogenesis and remodeling.

scientific article published on 12 March 2018

Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease ⬇️

scientific article published on June 23, 2011

Natural human apoA-I mutations L141RPisa and L159RFIN alter HDL structure and functionality and promote atherosclerosis development in mice.

scientific article published on 24 August 2015

Structure-function analysis of naturally occurring apolipoprotein A-I L144R, A164S and L178P mutants provides insight on their role on HDL levels and cardiovascular risk

scientific article published on 14 July 2020

Study of the Involvement of Phosphatidic Acid Formation in the Expression of Wound-Responsive Genes in Cotton

scientific article published on 01 June 2018

Thermodynamic and structural destabilization of apoE3 by hereditary mutations associated with the development of lipoprotein glomerulopathy ⬇️

scientific article published on October 30, 2012

Thermodynamic destabilization and aggregation propensity as the underlying mechanism behind the genetic association of apoE3 mutants and Lipoprotein Glomerulopathy

scientific article published on 11 October 2018

apoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL.

scientific article

List of works by Angeliki Chroni

A possible structural basis behind the pathogenic role of apolipoprotein E hereditary mutations associated with lipoprotein glomerulopathy.

A simple approach for human recombinant apolipoprotein E4 expression and purification.

Allele-dependent thermodynamic and structural perturbations in ApoE variants associated with the correction of dyslipidemia and formation of spherical ApoE-containing HDL particles.

Amyloid-peptide β 42 enhances the oligomerization and neurotoxicity of apoE4: the C-terminal residues Leu279, Lys282 and Gln284 modulate the structural and functional properties of apoE4

An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines ⬇️

Antisense oligonucleotides, microRNAs, and antibodies.

ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and Aβ production independently of their cholesterol efflux capacity

Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia ⬇️

Carboxyl Terminus of Apolipoprotein A-I (ApoA-I) Is Necessary for the Transport of Lipid-free ApoA-I but Not Prelipidated ApoA-I Particles through Aortic Endothelial Cells ⬇️

Characterization of antioxidant/anti-inflammatory properties and apoA-I-containing subpopulations of HDL from family subjects with monogenic low HDL disorders ⬇️

Cholesterol efflux and reverse cholesterol transport

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages

Domains of apoE4 required for the biogenesis of apoE-containing HDL.

Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux.

Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells.

HDL biogenesis, remodeling, and catabolism.

HDL dysfunction caused by mutations in apoA-I and other genes that are critical for HDL biogenesis and remodeling.

Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease ⬇️

Natural human apoA-I mutations L141RPisa and L159RFIN alter HDL structure and functionality and promote atherosclerosis development in mice.

Structure-function analysis of naturally occurring apolipoprotein A-I L144R, A164S and L178P mutants provides insight on their role on HDL levels and cardiovascular risk

Study of the Involvement of Phosphatidic Acid Formation in the Expression of Wound-Responsive Genes in Cotton

Thermodynamic and structural destabilization of apoE3 by hereditary mutations associated with the development of lipoprotein glomerulopathy ⬇️

Thermodynamic destabilization and aggregation propensity as the underlying mechanism behind the genetic association of apoE3 mutants and Lipoprotein Glomerulopathy

apoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL.