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List of works by Noriyasu Hirasawa

A Role of Peripheral Leukocytes in Vascular Permeability and Edema Formation in Air Pouch Type Allergic Inflammation in Rats ⬇️

scientific article published on 01 May 1991

A chalcone derivative suppresses the induction of TSLP in mice and human keratinocytes and attenuates OVA-induced antibody production in mice

scientific article published on 10 February 2019

A steroid alkaloid derivative 02F04 upregulates thymic stromal lymphopoietin expression slowly and continuously through a novel Gq/11-ROCK-ERK1/2 signaling pathway in mouse keratinocytes

scientific article published on 19 January 2019

All-Trans Retinoic Acid Enhances Antibody Production by Inducing the Expression of Thymic Stromal Lymphopoietin Protein

scientific article published on 02 March 2018

Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment:establishment of a modified allergic dermatitis model in mouse ear lobes by application of 12-O-tetradecanoyl phorbol 13-acetate: putat

scientific article published on July 2009

Analysis of the mechanism regulating the stability of rat macrophage inflammatory protein‐2 mRNA in RBL‐2H3 cells ⬇️

scientific article published on December 1, 2003

Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) polymorphisms in cases of lung cancer in Japan.

scientific article published on 26 July 2011

Biochemical assay of G protein-coupled receptor oligomerization: adenosine A1 and thromboxane A2 receptors form the novel functional hetero-oligomer

scientific article

CYP2A13 Genetic Polymorphisms in Relation to the Risk of Bladder Cancer in Japanese Smokers.

scientific article published on January 2016

CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers

scientific article published on 18 April 2015

Characterization of Methylated Bovine Serum Albumin-Induced Allergic Inflammation in Rats ⬇️

scientific article published on January 1, 1991

Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS)

article

Down-regulation of Na+/H+ exchanger 1 by Toll-like receptor stimulation in macrophages.

scientific article published on 11 October 2016

Downward regulation of neutrophil infiltration by endogenous histamine without affecting vascular permeability responses in air-pouch-type carrageenin inflammation in rats ⬇️

scientific article published on 01 April 1991

EGFR transactivation is involved in TNF-α-induced expression of thymic stromal lymphopoietin in human keratinocyte cell line.

scientific article published on 18 December 2017

Enhancement of inflammatory protein expression and nuclear factor Κb (NF-Κb) activity by trichostatin A (TSA) in OP9 preadipocytes

scientific article

Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide.

scientific article

Enhancement of nickel elution by lipopolysaccharide-induced inflammation ⬇️

scientific article published on January 14, 2011

Ergosterol and its derivatives from Grifola frondosa inhibit antigen-induced degranulation of RBL-2H3 cells by suppressing the aggregation of high affinity IgE receptors

scientific article published on 02 July 2018

Evaluation of personal dose equivalent using optically stimulated luminescent dosemeters in Marumori after the Fukushima nuclear accident.

scientific article published on 17 September 2012

Exacerbation of allergic diseases by chemicals: role of TSLP.

scientific article published on 04 March 2014

Expression of Histidine Decarboxylase and Its Roles in Inflammation

scientific article published on 16 January 2019

Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals

scientific article published on 16 May 2018

Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.

scientific article published on 14 December 2016

Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid ω-hydroxylation

scientific article published on 28 September 2014

Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation.

scientific article

Functional characterization of 20 allelic variants of CYP1A2

scientific article published on 27 March 2015

Functional characterization of 21 CYP2C19 allelic variants for clopidogrel 2-oxidation

scientific article published on 08 July 2014

Functional characterization of 21 allelic variants of dihydropyrimidinase.

scientific article published on 19 June 2017

Functional characterization of 32 CYP2C9 allelic variants.

scientific article published on 11 June 2013

Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation

scientific article published on 08 September 2018

Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation

scientific article published on 25 August 2018

Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation.

scientific article published on 22 November 2017

Functional characterization of CYP2B6 allelic variants in demethylation of antimalarial artemether

scientific article published on 11 July 2011

Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene.

scientific article published on October 2010

Functional characterization of wild-type and 49 CYP2D6 allelic variants for N-desmethyltamoxifen 4-hydroxylation activity

scientific article published on 18 March 2014

Genetic Polymorphisms of CYP2A6 in a Case-Control Study on Bladder Cancer in Japanese Smokers

scientific article published on 01 January 2016

Genetic polymorphisms of dihydropyrimidinase in a Japanese patient with capecitabine-induced toxicity

scientific article

Glucagon-like peptide-1 production in the GLUTag cell line is impaired by free fatty acids via endoplasmic reticulum stress.

scientific article published on 25 February 2014

Glucocorticoids decrease the production of glucagon-like peptide-1 at the transcriptional level in intestinal L-cells

scientific article published on 17 February 2015

High frequencies of positive nickel/cobalt patch tests and high sweat nickel concentration in patients with intrinsic atopic dermatitis.

scientific article published on 12 August 2013

Histamine synthesis is required for granule maturation in murine mast cells.

scientific article published in October 2013

Hypoxia inhibits TNF-α-induced TSLP expression in keratinocytes

scientific article published on 04 November 2019

Identification of a cell line producing high levels of TSLP: advantages for screening of anti-allergic drugs

scientific article published on 16 November 2013

Identification of histamine-production-increasing factor produced by stimulated RBL-2H3 rat basophilic leukemia cells as granulocyte-macrophage colony-stimulating factor ⬇️

scientific article published on July 24, 1998

Induced histamine regulates Ni elution from an implanted Ni wire in mice by downregulating neutrophil migration.

scientific article published on 13 February 2017

Induction of neutrophil infiltration by rat chemotactic cytokine (CINC) and its inhibition by dexamethasone in rats

scientific article published on 01 April 1992

Induction of thymic stromal lymphopoietin by a steroid alkaloid derivative in mouse keratinocytes

scientific article published on 5 December 2017

Induction of thymic stromal lymphopoietin production by nonanoic acid and exacerbation of allergic inflammation in mice.

scientific article published on 25 September 2013

Induction of thymic stromal lymphopoietin production by xylene and exacerbation of picryl chloride-induced allergic inflammation in mice.

scientific article published on 7 October 2011

Influence of Japanese Regulatory Action on Denosumab-Related Hypocalcemia Using Japanese Adverse Drug Event Report Database.

scientific article published in January 2017

Inhibitory effects of nicotine derived from cigarette smoke on thymic stromal lymphopoietin production in epidermal keratinocytes.

scientific article published on 4 January 2016

Intrinsic atopic dermatitis shows high serum nickel concentration

scientific article published on 12 February 2015

Involvement of COX-2 in nickel elution from a wire implanted subcutaneously in mice.

scientific article published on 21 July 2016

Kinetics of 6-Thioxanthine Metabolism by Allelic Variants of Xanthine Oxidase ⬇️

scientific article published on January 1, 2010

LPS priming in early life decreases antigen uptake of dendritic cells via NO production

scientific article published on 9 October 2017

Lipopolysaccharide-Activated Leukocytes Enhance Thymic Stromal Lymphopoietin Production in a Mouse Air-Pouch-Type Inflammation Model.

scientific article published on 7 June 2016

Negative Regulation of MAP Kinase by Diacylglycerol-dependent Mechanisms via G Protein-coupled Receptors in Rat Basophilic RBL-2H3 (m1) Cells ⬇️

scientific article published on May 1, 1997

Nickel ions bind to HSP90β and enhance HIF-1α-mediated IL-8 expression

scientific article published on 16 January 2018

Nickel ions selectively inhibit lipopolysaccharide-induced interleukin-6 production by decreasing its mRNA stability.

scientific article published on 5 March 2015

Non-24-hour sleep-wake syndrome improved by low-dose valproic acid: a case report.

scientific article published on 13 December 2016

Novel single nucleotide polymorphism of the CYP2A13 gene in Japanese individuals

scientific article published on 24 May 2011

Novel single nucleotide polymorphisms of the dihydropyrimidinase gene (DPYS) in Japanese individuals

scientific article published on 28 September 2014

Outcomes of a Long-term Case Review Program during the On-site Training of Pharmacy Students.

scientific article published on 28 April 2015

Pentanoic acid induces thymic stromal lymphopoietin production through Gq/11 and Rho-associated protein kinase signaling pathway in keratinocytes

scientific article published on 3 July 2017

Points-to-consider documents: Scientific information on the evaluation of genetic polymorphisms during non-clinical studies and phase I clinical trials in the Japanese population

scientific article published on 15 March 2018

Rapid and sensitive multiplex single-tube nested PCR for the identification of five human Plasmodium species.

scientific article published on 25 January 2018

Regulation of dipeptidyl peptidase 4 production in adipocytes by glucose

scientific article published on 24 May 2014

Retinoid signaling in pathological remodeling related to cardiovascular disease

scientific article

Role of Phosphatidylinositol 3-Kinase in Degranulation Induced by IgE-dependent and -independent Mechanisms in Rat Basophilic RBL-2H3 (ml) Cells ⬇️

scientific article published on May 1, 1997

Stimulation of arachidonic acid metabolism by a streptococcal preparation (OK-432) in rat peritoneal macrophages

scientific article published on February 14, 1992

Suppression of Intracellular Calcium Levels and Inhibition of Degranulation in RBL-2H3 Mast Cells by the Sesquiterpene Lactone Parthenolide ⬇️

scientific article published on September 2, 2010

Suppression of the antigen-stimulated RBL-2H3 mast cell activation by Artekeiskeanol A.

scientific article

The Anti-Inflammatory Effects of Lion's Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages.

scientific article published on January 2015

The antagonism of histamine H1 and H4 receptors ameliorates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice

scientific article published on 12 June 2012

The role of histamine H1 and H4 receptors in atopic dermatitis: from basic research to clinical study

scientific article published on December 2014

Zinc ions have a potential to attenuate both Ni ion uptake and Ni ion-induced inflammation

scientific article published on 13 February 2018

[Education for six-years graduate school of pharmaceutical sciences: a case of Tohoku University]

scientific article published on 01 January 2011

[Education of graduate school of pharmaceutical sciences in new generation: introduction]

scientific article published on 01 January 2011

[TSLP-basophil axis]

scientific article published on 01 February 2014

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