List of works - Chandraiah Godugu

A Review on Pharmacological properties of Coumarins

scientific article

A facile I2-catalyzed synthesis of imidazo[1,2-a]pyridines via sp3 C-H functionalization of azaarenes and evaluation of anticancer activity

scientific article published on 01 August 2017

AlgiMatrix™-Based 3D Cell Culture System as an In Vitro Tumor Model: An Important Tool in Cancer Research

scientific article published on January 2016

An Adaptogen: Withaferin A Ameliorates in Vitro and in Vivo Pulmonary Fibrosis by Modulating the Interplay of Fibrotic, Matricelluar Proteins, and Cytokines.

scientific article

Andrographolide ameliorates silica induced pulmonary fibrosis

scientific article published on 20 July 2018

Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid.

scientific article

Borneol protects against cerulein-induced oxidative stress and inflammation in acute pancreatitis mice model

scientific article published on 09 November 2020

Cardioprotective effects of nanoceria in a murine model of cardiac remodeling

scientific article published on 17 July 2018

Cerulein-induced chronic pancreatitis in Swiss albino mice: An improved short-term model for pharmacological screening

scientific article published on 23 January 2019

Crocin, an active constituent of Crocus sativus ameliorates cerulein induced pancreatic inflammation and oxidative stress

scientific article published on 25 November 2019

Cytotoxicity of Nanomaterials: Nanotoxicology to Address the Safety Concerns of Nanoparticles

scientific article published on 23 October 2017

Design and Synthesis of DNA-Interactive β-Carboline-Oxindole Hybrids as Cytotoxic and Apoptosis-Inducing Agents

scientific article published on 22 August 2018

Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition study

scientific article published on 10 August 2019

Dramatic improvement in pharmacokinetic and pharmacodynamic effects of sustain release curcumin microparticles demonstrated in experimental type 1 diabetes model

scientific article published on 04 February 2019

Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity

scientific article

Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity

scientific article published on 21 September 2019

Facile synthesis of 2-aryl 5-hydroxy benzo[d]oxazoles and their in vitro anti-proliferative effects on various cancer cell lines

scientific article published on 26 October 2018

First report on the pharmacokinetic profile of nimbolide, a novel anticancer agent in oral and intravenous administrated rats by LC/MS method

scientific article published on 02 June 2018

Folate-decorated PLGA nanoparticles as a rationally designed vehicle for the oral delivery of insulin

scientific article published on 14 May 2012

Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC).

scientific article published on 23 January 2017

Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-β/Smad signaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo

scientific article published on 04 February 2020

Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention

scientific article published on 15 July 2018

Liposphere mediated topical delivery of thymoquinone in the treatment of psoriasis.

scientific article published on 22 June 2017

Modulation of cerulein-induced pancreatic inflammation by hydroalcoholic extract of curry leaf (Murraya koenigii)

scientific article published on 18 March 2019

Nanoceria ameliorates doxorubicin induced cardiotoxicity: Possible mitigation via reduction of oxidative stress and inflammation.

scientific article published in February 2018

Nanomiemgel--a novel drug delivery system for topical application--in vitro and in vivo evaluation

scientific article

Nanoyttria attenuates isoproterenol-induced cardiac injury

scientific article published on 03 December 2018

Niclosamide alleviates pulmonary fibrosis in vitro and in vivo by attenuation of epithelial-to-mesenchymal transition, matrix proteins & Wnt/β-catenin signaling: A drug repurposing study

scientific article published on 03 January 2019

Nimbolide ameliorates fibrosis and inflammation in experimental murine model of bleomycin-induced scleroderma

scientific article published on 14 September 2018

Nimbolide ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibition of TGF-β and EMT/Slug signalling

scientific article published on 12 June 2019

Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer

scientific article published on 17 May 2018

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation

scientific article published on 28 January 2019

Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma

scientific article published on 19 August 2015

Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer.

scientific article published on 29 August 2016

Oral bioavailability, therapeutic efficacy and reactive oxygen species scavenging properties of coenzyme Q10-loaded polymeric nanoparticles.

scientific article published on 24 June 2011

Oropharyngeal administration of silica in Swiss mice: A robust and reproducible model of occupational pulmonary fibrosis

scientific article published on 28 June 2018

Oropharyngeal aspiration of bleomycin: An alternative experimental model of pulmonary fibrosis developed in Swiss mice

scientific article

Overview on Therapeutic Applications of Microparticulate Drug Delivery Systems.

scientific article published on January 2016

Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer

scientific article

Protective Effect of Nanoceria on Cisplatin-Induced Nephrotoxicity by Amelioration of Oxidative Stress and Pro-inflammatory Mechanisms

scientific article published on 25 July 2018

Protective effects of ambroxol in psoriasis like skin inflammation: Exploration of possible mechanisms

scientific article published on 29 March 2019

Repurposing an old drug for new use: Niclosamide in psoriasis-like skin inflammation

scientific article published on 17 December 2019

Selenium nanoparticles induce autophagy mediated cell death in human keratinocytes

scientific article published on 29 July 2019

Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.

scientific article published in March 2018

Superoxide dismutase mimetic nanoceria restrains cerulein induced acute pancreatitis

scientific article published on 03 July 2019

Sustained-Release Curcumin Microparticles for Effective Prophylactic Treatment of Exocrine Dysfunction of Pancreas: A Preclinical Study on Cerulein-Induced Acute Pancreatitis

scientific article published on 19 July 2018

Synthesis and biological evaluation of morpholines linked coumarin-triazole hybrids as anticancer agents

scientific article published on 01 September 2019

Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents.

scientific article published on 28 March 2018

Synthesis of enamino-2-oxindoles via conjugate addition between α-azido ketones and 3-alkenyl oxindoles: Cytotoxicity evaluation and apoptosis inducing studies

article

Synthesis of substituted biphenyl methylene indolinones as apoptosis inducers and tubulin polymerization inhibitors

scientific article published on 29 January 2019

Tankyrase as a Novel Molecular Target in Cancer and Fibrotic Diseases.

scientific article published on 15 July 2016

Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer

scientific article published on 07 December 2020

The Role of Plant-derived Products in Pancreatitis: Experimental and Clinical Evidence.

scientific article published on 15 March 2017

The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen

scientific article published on 08 October 2010

Therapeutic applications of selenium nanoparticles

scientific article published on 04 January 2019

Therapeutic effects of Nimbolide, an autophagy regulator, in ameliorating pulmonary fibrosis through attenuation of TGF-β1 driven epithelial-to-mesenchymal transition

scientific article published on 01 August 2019

Topical administration of dual siRNAs using fusogenic lipid nanoparticles for treating psoriatic-like plaques

Toxicity of multiwalled carbon nanotubes with end defects critically depends on their functionalization density

scientific article published on 18 October 2011

Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction

scientific article published on 22 February 2019

Withaferin A ameliorates renal injury due to its potent effect on inflammatory signaling

scientific article published on 12 June 2019

Withaferin A attenuates bleomycin-induced scleroderma by targeting FoxO3a and NF-κβ signaling: Connecting fibrosis and inflammation

scientific article published on 27 October 2018

Withaferin A reverses bile duct ligation-induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signaling

scientific article published on 23 July 2019

Withaferin A, a novel compound of Indian ginseng (Withania somnifera), ameliorates Cerulein-induced acute pancreatitis: Possible role of oxidative stress and inflammation

scientific article published on 11 October 2018

Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes

scientific article published on 24 July 2018

Yttrium oxide nanoparticles reduce the severity of acute pancreatitis caused by cerulein hyperstimulation

scientific article published on 06 March 2019

List of works by Chandraiah Godugu

A Review on Pharmacological properties of Coumarins

A facile I2-catalyzed synthesis of imidazo[1,2-a]pyridines via sp3 C-H functionalization of azaarenes and evaluation of anticancer activity

AlgiMatrix™-Based 3D Cell Culture System as an In Vitro Tumor Model: An Important Tool in Cancer Research

An Adaptogen: Withaferin A Ameliorates in Vitro and in Vivo Pulmonary Fibrosis by Modulating the Interplay of Fibrotic, Matricelluar Proteins, and Cytokines.

Andrographolide ameliorates silica induced pulmonary fibrosis

Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid.

Borneol protects against cerulein-induced oxidative stress and inflammation in acute pancreatitis mice model

Cardioprotective effects of nanoceria in a murine model of cardiac remodeling

Cerulein-induced chronic pancreatitis in Swiss albino mice: An improved short-term model for pharmacological screening

Crocin, an active constituent of Crocus sativus ameliorates cerulein induced pancreatic inflammation and oxidative stress

Cytotoxicity of Nanomaterials: Nanotoxicology to Address the Safety Concerns of Nanoparticles

Design and Synthesis of DNA-Interactive β-Carboline-Oxindole Hybrids as Cytotoxic and Apoptosis-Inducing Agents

Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition study

Dramatic improvement in pharmacokinetic and pharmacodynamic effects of sustain release curcumin microparticles demonstrated in experimental type 1 diabetes model

Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity

Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity

Facile synthesis of 2-aryl 5-hydroxy benzo[d]oxazoles and their in vitro anti-proliferative effects on various cancer cell lines

First report on the pharmacokinetic profile of nimbolide, a novel anticancer agent in oral and intravenous administrated rats by LC/MS method

Folate-decorated PLGA nanoparticles as a rationally designed vehicle for the oral delivery of insulin

Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC).

Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-β/Smad signaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo

Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention

Liposphere mediated topical delivery of thymoquinone in the treatment of psoriasis.

Modulation of cerulein-induced pancreatic inflammation by hydroalcoholic extract of curry leaf (Murraya koenigii)

Nanoceria ameliorates doxorubicin induced cardiotoxicity: Possible mitigation via reduction of oxidative stress and inflammation.

Nanomiemgel--a novel drug delivery system for topical application--in vitro and in vivo evaluation

Nanoyttria attenuates isoproterenol-induced cardiac injury

Niclosamide alleviates pulmonary fibrosis in vitro and in vivo by attenuation of epithelial-to-mesenchymal transition, matrix proteins & Wnt/β-catenin signaling: A drug repurposing study

Nimbolide ameliorates fibrosis and inflammation in experimental murine model of bleomycin-induced scleroderma

Nimbolide ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibition of TGF-β and EMT/Slug signalling

Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation

Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma

Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer.

Oral bioavailability, therapeutic efficacy and reactive oxygen species scavenging properties of coenzyme Q10-loaded polymeric nanoparticles.

Oropharyngeal administration of silica in Swiss mice: A robust and reproducible model of occupational pulmonary fibrosis

Oropharyngeal aspiration of bleomycin: An alternative experimental model of pulmonary fibrosis developed in Swiss mice

Overview on Therapeutic Applications of Microparticulate Drug Delivery Systems.

Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer

Protective Effect of Nanoceria on Cisplatin-Induced Nephrotoxicity by Amelioration of Oxidative Stress and Pro-inflammatory Mechanisms

Protective effects of ambroxol in psoriasis like skin inflammation: Exploration of possible mechanisms

Repurposing an old drug for new use: Niclosamide in psoriasis-like skin inflammation

Selenium nanoparticles induce autophagy mediated cell death in human keratinocytes

Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.

Superoxide dismutase mimetic nanoceria restrains cerulein induced acute pancreatitis

Sustained-Release Curcumin Microparticles for Effective Prophylactic Treatment of Exocrine Dysfunction of Pancreas: A Preclinical Study on Cerulein-Induced Acute Pancreatitis

Synthesis and biological evaluation of morpholines linked coumarin-triazole hybrids as anticancer agents

Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents.

Synthesis of enamino-2-oxindoles via conjugate addition between α-azido ketones and 3-alkenyl oxindoles: Cytotoxicity evaluation and apoptosis inducing studies

Synthesis of substituted biphenyl methylene indolinones as apoptosis inducers and tubulin polymerization inhibitors

Tankyrase as a Novel Molecular Target in Cancer and Fibrotic Diseases.

Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer

The Role of Plant-derived Products in Pancreatitis: Experimental and Clinical Evidence.

The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen

Therapeutic applications of selenium nanoparticles

Therapeutic effects of Nimbolide, an autophagy regulator, in ameliorating pulmonary fibrosis through attenuation of TGF-β1 driven epithelial-to-mesenchymal transition

Topical administration of dual siRNAs using fusogenic lipid nanoparticles for treating psoriatic-like plaques

Toxicity of multiwalled carbon nanotubes with end defects critically depends on their functionalization density

Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction

Withaferin A ameliorates renal injury due to its potent effect on inflammatory signaling

Withaferin A attenuates bleomycin-induced scleroderma by targeting FoxO3a and NF-κβ signaling: Connecting fibrosis and inflammation

Withaferin A reverses bile duct ligation-induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signaling

Withaferin A, a novel compound of Indian ginseng (Withania somnifera), ameliorates Cerulein-induced acute pancreatitis: Possible role of oxidative stress and inflammation

Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes

Yttrium oxide nanoparticles reduce the severity of acute pancreatitis caused by cerulein hyperstimulation