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List of works by Oliver Grottke

A new model for blunt liver injuries in the swine

scientific article published on 09 December 2009

Antifouling Microparticles To Scavenge Lipopolysaccharide from Human Blood Plasma

scientific article published on 22 January 2019

Automatic Control of Veno-Venous Extracorporeal Lung Assist

scientific article published on 5 February 2016

Coagulation Management in Jersey Calves: An ex vivo Study

scientific article published on 27 January 2017

Coagulation factor concentrates and point-of-care coagulation monitoring: both might be essential for optimal treatment of trauma-induced coagulopathy.

scientific article

Comparing the viscoelastomeric fibrin polymerization assays FIBTEM® (ROTEM) vs. Functional Fibrinogen® (TEG): or why is a higher threshold for fibrinogen substitution better than a lower one?

scientific article published on 01 September 2016

Comparison between the new fully automated viscoelastic coagulation analysers TEG 6s and ROTEM Sigma in trauma patients: A prospective observational study

scientific article published on 01 November 2019

Correction to: Sub-anesthetic Xenon Increases Erythropoietin Levels in Humans: A Randomized Controlled Trial.

scientific article

Cortisol and alpha-amylase as stress response indicators during pre-hospital emergency medicine training with repetitive high-fidelity simulation and scenarios with standardized patients

scientific article

Direct Oral Anticoagulants in Emergency Trauma Admissions.

scientific article published on September 2016

Dose requirements for idarucizumab reversal of dabigatran in a lethal porcine trauma model with continuous bleeding

scientific article published on 20 April 2017

Effects of Fibrinogen Concentrate on Thrombin Generation, Thromboelastometry Parameters, and Laboratory Coagulation Testing in a 24-Hour Porcine Trauma Model

scientific article published on 6 May 2015

Efficacy of idarucizumab, prothrombin complex concentrate (PCC) and activated PCC to reverse the anticoagulatory potential of dabigatran in a porcine polytrauma model.

scientific article published on 16 March 2015

Evaluation of combined idarucizumab and prothrombin complex concentrate treatment for bleeding related to dabigatran in a lethal porcine model of double trauma

scientific article published on 26 December 2018

Fibrin patch in a pig model with blunt liver injury under severe hypothermia.

scientific article published on 15 November 2013

Fibrinogen Supplementation and Its Indications

scientific article published on 01 October 2019

Fibrinogen concentrate does not suppress endogenous fibrinogen synthesis in a 24-hour porcine trauma model

scientific article published on 01 October 2014

Four-factor Prothrombin Complex Concentrate for the Management of Patients Receiving Direct Oral Activated Factor X Inhibitors

scientific article published on 01 November 2019

Glasgow Coma Scale and laboratory markers are superior to COHb in predicting CO intoxication severity

scientific article published on 29 April 2010

Hemostatic Therapy Using Tranexamic Acid and Coagulation Factor Concentrates in a Model of Traumatic Liver Injury.

scientific article

Idarucizumab in major trauma patients: a single centre real life experience

scientific article published on 25 September 2019

Idarucizumab, a Specific Dabigatran Reversal Agent, Reduces Blood Loss in a Porcine Model of Trauma With Dabigatran Anticoagulation

scientific article published on 01 September 2015

Idarucizumab, a Specific Reversal Agent for Dabigatran: Mode of Action, Pharmacokinetics and Pharmacodynamics, and Safety and Efficacy in Phase 1 Subjects.

scientific article

Idarucizumab, a specific reversal agent for dabigatran: mode of action, pharmacokinetics and pharmacodynamics, and safety and efficacy in phase 1 subjects

scientific article

Impact of Direct Oral Anticoagulants (DOACs) in Patients with Hip Fractures

scientific article published on 01 January 2019

In a trauma experimental pig model prothrombin complex concentrates and a specific antidote (idarucizumab) are effective to reverse the anticoagulant effects of dabigatran

In vitro comparison of the hemocompatibility of two centrifugal left ventricular assist devices

scientific article published on 06 August 2018

Influence of a freeze-thaw cycle on the stress-stretch curves of tissues of porcine abdominal organs

scientific article published on 04 August 2012

Influence of temperature on the positive inotropic effect of levosimendan, dobutamine and milrinone.

scientific article published on November 2009

Is "Thrombin Burst" Now the Worst Option in Trauma?

scientific article published on 01 June 2017

Measurement of dabigatran in standardly used clinical assays, whole blood viscoelastic coagulation, and thrombin generation assays

scientific article

Microfluidic cell sorting: Towards improved biocompatibility of extracorporeal lung assist devices.

scientific article published on 23 May 2018

Nonsurgical techniques to control massive bleeding.

scientific article

Perioperatively acquired disorders of coagulation.

scientific article published on April 2015

Plasma-derived Factor X therapy for treatment of intracranial bleeding in a patient with Factor X deficiency: a case report

scientific article published on 09 April 2019

Platelet-derived MIF: a novel platelet chemokine with distinct recruitment properties.

scientific article

Porcine blood and surrogate markers do not prove benefit of aDabi-Fab. Authors' response

Pre-hospital plasma transfusion: a valuable coagulation support or an expensive fluid therapy?

scientific article published on 01 July 2019

Prothrombin Complex Concentrate Is Effective in Treating the Anticoagulant Effects of Dabigatran in a Porcine Polytrauma Model.

scientific article published in December 2015

Prothrombin Complex Concentrate-induced Disseminated Intravascular Coagulation Can Be Prevented by Coadministering Antithrombin in a Porcine Trauma Model

scientific article published on 01 September 2019

Prothrombin complex concentrate (PCC) for the treatment of coagulopathy associated with massive bleeding

scientific article published on 01 December 2010

Prothrombin complex concentrate reduces blood loss and enhances thrombin generation in a pig model with blunt liver injury under severe hypothermia

scientific article published on 08 September 2011

Prothrombin complex concentrate restores haemostasis in a dabigatran anticoagulated polytrauma pig model

Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

scientific article published on 5 February 2014

Prothrombin complex concentrates in trauma and perioperative bleeding

scientific article published on April 2015

Re: Three versus four-factor prothrombin complex concentrates for "factor-based" resuscitation in a porcine hemorrhagic shock model.

scientific article published in January 2018

Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia

scientific article published on 22 June 2015

Recombinant factor VIIa reduces bleeding after blunt liver injury in coagulopathic, hypofibrinogenaemic pigs

scientific article published on 06 October 2010

Reply to Faraoni D, Fenger-Eriksen C, Gillard S et al. Evaluation of dynamic parameters of thrombus formation measured on whole blood using rotational thromboelastometry in children undergoing cardiac surgery: a descriptive study

scientific article published on 01 June 2015

Reversal of dabigatran anticoagulation ex vivo: Porcine study comparing prothrombin complex concentrates and idarucizumab.

scientific article

Reversal of dabigatran by intraosseous or intravenous idarucizumab in a porcine polytrauma model

scientific article published on 09 March 2018

Reversing Dabigatran Anticoagulation with Prothrombin Complex Concentrate versus Idarucizumab as Part of Multimodal Hemostatic Intervention in an Animal Model of Polytrauma

scientific article published on 30 August 2017

Septic porcine blood does not further activate coagulation during in vitro membrane oxygenation.

scientific article published on 2 November 2016

Sub-anesthetic Xenon Increases Erythropoietin Levels in Humans: A Randomized Controlled Trial.

scientific article

Supplementary fibrinogen in the management of bleeding: re-evaluation of data from clinical trials.

scientific article published on 5 December 2017

Survival of HeartMate II Patients Despite Cessation of Anticoagulation　- Outcomes and Hemostatic Analysis

scientific article published on 12 December 2017

The Renal Elimination Pathways of the Dabigatran Reversal Agent Idarucizumab and its Impact on Dabigatran Elimination

scientific article published on 13 March 2018

The Reversal of Direct Oral Anticoagulants in Animal Models

scientific article

The impact of direct oral anticoagulants in traumatic brain injury patients greater than 60-years-old.

scientific article

The relevance of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentration for postoperative infections and postoperative organ dysfunctions in cardiac surgery patients: The eVIDenCe study

scientific article published on 13 December 2018

Theoretical Modeling of Coagulation Management With Therapeutic Plasma or Prothrombin Complex Concentrate.

scientific article published on 24 August 2017

Therapeutic Plasma Transfusion in Bleeding Patients: A Systematic Review

scientific article

Therapy with activated prothrombin complex concentrate is effective in reducing dabigatran-associated blood loss in a porcine polytrauma model.

scientific article

Thrombin generation capacity of prothrombin complex concentrate in an in vitro dilutional model.

scientific article

Tissue oxygen saturation as an early indicator of delayed lactate clearance after cardiac surgery: a prospective observational study.

scientific article published on 30 October 2015

Transient or extended reversal of apixaban anticoagulation by andexanet alfa is equally effective in a porcine polytrauma model

scientific article published on 13 June 2019

Twelve Hours In Vitro Biocompatibility Testing of Membrane Oxygenators.

scientific article published on 4 May 2015

Use of a specific antidote to dabigatran (idarucizumab) reduces blood loss and mortality in dabigatran-induced and trauma-induced bleeding in pigs

scientific article

Virtual reality-based simulator for training in regional anaesthesia.

scientific article published on 25 August 2009

Visualization of fibrinogen-dependent thrombus formation*.

scientific article

Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution

scientific article published in PLoS ONE

[Comment on: Andexanet alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.]

scientific article published on 01 December 2016

[Dealing with massive bleeding and associated perioperative coagulopathy: recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine]

scientific article published on 01 March 2013

[Individualized coagulation therapy: Wish or already reality?]

scientific article published on 01 October 2015

[Management of hemorrhage in patients treated with direct oral anticoagulants].

scientific article published on 28 April 2017

[Prehospital plasma transfusion in civilian trauma patients in hemorrhagic shock]

scientific article published on 01 December 2018

[Rotational thromboelastometry for the diagnosis of coagulation disorders].

scientific article published on 12 July 2016

[Safer in everyday clinical care].

scientific article published in November 2015

[Treatment of massive bleeding: summary of the updated European guidelines]

scientific article published on 01 June 2011

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