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List of works by Gilberto Fronza

3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.

scientific article

Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival

scientific article published on 19 February 2019

Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: clarifying the role of N3-methyladenine.

scientific article

Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

scientific article

Effect of N3‐Methyladenine and an Isosteric Stable Analogue on DNA Polymerization ⬇️

scientific article published on September 19, 2010

Etoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation

scientific article published in Scientific Reports

Gambogic acid counteracts mutant p53 stability by inducing autophagy.

scientific article published on 26 November 2016

Heterogeneousp53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonalc-myc andVDJ rearrangements ⬇️

scientific article published on December 10, 1997

High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells.

scientific article published on September 2009

Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.

scientific article

MDM2SNP309 genotype influences survival of metastatic but not of localized neuroblastoma

scientific article published on 01 October 2009

Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair.

scientific article published on January 2010

NEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome

scientific article published on 13 March 2020

P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.

scientific article

P63 modulates the expression of the WDFY2 gene which is implicated in cancer regulation and limb development

scientific article published on 01 December 2019

PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells.

scientific article published on 12 October 2010

PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53.

scientific article published on 29 March 2013

Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent.

scientific article published on 7 January 2008

SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations

scientific article published on 16 September 2019

Structural studies on mechanisms to activate mutant p53.

scientific article published on January 2014

Studying p53 family proteins in yeast: induction of autophagic cell death and modulation by interactors and small molecules.

scientific article published on 28 September 2014

TP53 mutants in the tower of babel of cancer progression

scientific article published on 14 March 2014

TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear.

scientific article published on 14 August 2017

The 4-nitroquinoline 1-oxide mutational spectrum in single stranded DNA is characterized by guanine to pyrimidine transversions ⬇️

scientific article published on March 25, 1992

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.

scientific article published on 17 November 2012

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

scientific article

Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer ⬇️

scientific article published on May 1, 1998

Validation of a survival-risk score (SRS) in relapsed/refractory CLL patients treated with idelalisib-rituximab

scientific article published on 16 September 2020

Yeast As a Chassis for Developing Functional Assays to Study Human P53

scientific article published on 04 August 2019

p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system

scientific article

∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites

scientific article

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