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List of works by Markus Hoffmann

A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism

scientific article published on 13 June 2018

A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry.

scientific article published on 22 February 2017

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

scientific article published in 2021

A system for production of defective interfering particles in the absence of infectious influenza A virus

scientific article published on 01 March 2019

Analysis of Resistance of Ebola Virus Glycoprotein-Driven Entry Against MDL28170, An Inhibitor of Cysteine Cathepsins

scientific article published on 15 October 2019

Calu-3 cells are largely resistant to entry driven by filovirus glycoproteins and the entry defect can be rescued by directed expression of DC-SIGN or cathepsin L

scientific article published on 03 April 2019

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

scientific article published on 05 August 2020

Cell Entry of Influenza A Viruses: Sweet Talk between HA and Ca V 1.2

scholarly article published by Markus Hoffmann in 2018

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

scientific article published on 22 July 2020

Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

scientific article

Development and Evaluation of Peptidomimetic Compounds Against SARS-CoV-2 Spike Protein: an In Silico and In Vitro Study

scientific article published on 23 January 2022

Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.

scientific article

Disease Manifestation and Viral Sequences in a Bonobo More Than 30 Years after Papillomavirus Infection

scientific article published on 26 January 2019

Dynamic Ca<sup>2+</sup> sensitivity stimulates the evolved SARS-CoV-2 spike strain-mediated membrane fusion for enhanced entry

scientific article published on 09 April 2022

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein

scientific article published in Scientific Reports

Fusogenicity of the Ghana Virus (Henipavirus: Ghanaian bat henipavirus) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein

scientific article published on 29 August 2019

LY6E impairs coronavirus fusion and confers immune control of viral disease

scientific article published on 23 July 2020

Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods

scientific article published on 02 November 2020

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

scientific article published in 2022

Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance

scientific article published on 01 June 2019

Mutations in the spike protein of MERS-CoV transmitted in Korea increase resistance towards antibody-mediated neutralization

scientific article published on 04 January 2019

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

scientific article published in December 2020

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

scientific article published on 12 January 2022

Recombinant mumps viruses expressing the batMuV fusion glycoprotein are highly fusion active and neurovirulent

scientific article published on 2 September 2016

Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner

scientific article published on 01 February 2019

Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques

scientific article published on 04 November 2019

SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants

scientific article published on 06 July 2021

Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells

scientific article published in September 2019

Spike residue 403 affects binding of coronavirus spikes to human ACE2

scientific article published on 25 November 2021

TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1

scientific article published in Journal of Biological Chemistry

Tetherin inhibits Nipah virus but not Ebola virus replication in fruit bat cells

scientific article published on 17 January 2019

The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.

scientific article

The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells

scientific article

The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection

scientific article published on 01 October 2021

The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells.

scientific article published on 7 December 2017

The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

scientific article published on 31 January 2020

Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins

scientific article published on 2 November 2016

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