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List of works by Jonathan M Tyrrell

A promising target for treatment of multidrug-resistant bacterial infections.

scientific article published on 2 May 2011

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

scientific article published on 16 September 2019

Clinical validation of the SensiTest™ Colistin, a broth microdilution based method to evaluate colistin MICs.

scientific article

Crystal structures of VIM-1 complexes explain active site heterogeneity in VIM-class metallo-β-lactamases

scientific article published on 23 November 2018

Dissemination of genetically diverse NDM-1, -5, -7 producing-Gram-negative pathogens isolated from pediatric patients in Pakistan

scientific article published on 31 May 2019

Genetic & virulence profiling of ESBL-positive E. coli from nosocomial & veterinary sources

scientific article published on 18 February 2016

Heavy Metal Resistance Genes Are Associated with blaNDM-1- and blaCTX-M-15-Carrying Enterobacteriaceae.

scientific article

Heterogeneous and Flexible Transmission of mcr-1 in Hospital-Associated Escherichia coli.

scientific article

In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii

scientific article published on 01 April 2019

Novel partners with colistin to increase its in vivo therapeutic effectiveness and prevent the occurrence of colistin resistance in NDM- and MCR-co-producing Escherichia coli in a murine infection model

scientific article published on 01 January 2019

Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study.

scientific article published on 27 January 2017

Profiling interactions of vaborbactam with metallo-β-lactamases

scientific article published on 17 May 2019

Structure-activity studies on polymyxin derivatives carrying three positive charges only reveal a new class of compounds with strong antibacterial activity.

scientific article published on 11 March 2017

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

scientific article published in April 2019

The polymyxin derivative NAB739 is synergistic with several antibiotics against polymyxin-resistant strains of Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii

scientific article published on 23 December 2018

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