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List of works by Lei Chen

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

scientific article

Activation mechanism of human soluble guanylate cyclase by stimulators and activators

scientific article published on 17 September 2021

Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.

scientific article published on 28 March 2018

Recent progress in structural studies on canonical TRP ion channels

scientific article published on 28 August 2019

Structural Insights into the Inhibitory Mechanism of Insulin Secretagogues on the Pancreatic ATP-Sensitive Potassium Channel

scientific article published on 14 October 2019

Structural identification of vasodilator binding sites on the SUR2 subunit

scientific article published on 13 May 2022

Structural insight into the autoinhibition mechanism of AMP-activated protein kinase

scientific article

Structural insight into the mechanism of synergistic autoinhibition of SAD kinases

scientific article

Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor

scientific article published on 18 May 2020

Structural insights into the mechanism of pancreatic K<sub>ATP</sub> channel regulation by nucleotides

scientific article published on 19 May 2022

Structure and dynamics of AMPA receptor GluA2 in resting, pre-open, and desensitized states

scientific article

Structure and mechanism of NALCN-FAM155A-UNC79-UNC80 channel complex

scientific article published on 12 May 2022

Structure of a Pancreatic ATP-Sensitive Potassium Channel.

scientific article published on 12 January 2017

Structure of the mechanosensitive OSCA channels

scientific article published on 06 September 2018

Structure of the receptor-activated human TRPC6 and TRPC3 ion channels

scientific article published on 26 April 2018

Structure of voltage-modulated sodium-selective NALCN-FAM155A channel complex

scientific article published on 03 December 2020

Structures of human dual oxidase 1 complex in low-calcium and high-calcium states

scientific article published on 08 January 2021

The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel

scientific article published on 01 May 2019

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism

scientific article