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List of works by Rolf D Issels

Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial

scientific article

An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma ⬇️

scientific article published on November 1, 2003

Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake ⬇️

scientific article published on February 9, 1998

Cancer Testis Antigens and Immunotherapy: Expression of PRAME Is Associated with Prognosis in Soft Tissue Sarcoma

scientific article published on 03 December 2020

Concomitant trimodality therapy of re-irradiation, chemotherapy and regional hyperthermia for a pretreated inoperable sarcoma recurrence.

scientific article published on March 2015

Current trials and new aspects in soft tissue sarcoma of adults

scientific article

Definition of extracellular localized epitopes of Hsp70 involved in an NK immune response ⬇️

scientific article published on March 1, 1998

Degradation of 2-(3-aminopropylamino)-ethanethiol (WR-1065) by Cu-dependent amine oxidases and influence on glutathione status of chinese hamster ovary cells ⬇️

scientific article published on 01 August 1995

Differential Hsp70 plasma-membrane expression on primary human tumors and metastases in mice with severe combined immunodeficiency ⬇️

scientific article published on September 11, 1998

Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial.

scientific article published on 15 February 2018

Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study

scientific article published in November 2014

Evaluation of several FDG PET parameters for prediction of soft tissue tumour grade at primary diagnosis and recurrence.

scientific article published on 19 February 2015

Ferrite-enhanced MRI monitoring in hyperthermia.

scientific article

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in October 2018

Gemcitabine and cisplatin combined with regional hyperthermia as second-line treatment in patients with gemcitabine-refractory advanced pancreatic cancer ⬇️

scientific article published on December 17, 2012

Gemcitabine treatment of rat soft tissue sarcoma with phosphatidyldiglycerol-based thermosensitive liposomes

scientific article published on 6 March 2014

Gene expression analysis using DNA microarrays in soft tissue and bone tumors ⬇️

scientific article published on September 26, 2003

Guidelines for time-to-event end point definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)†.

scientific article

Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application.

scientific article

Heat shock protein 70: role in antigen presentation and immune stimulation

scientific article

High-risk soft tissue sarcoma: clinical trial and hyperthermia combined chemotherapy.

scientific article

Hsp70, a messenger from hyperthermia for the immune system ⬇️

scientific article published on March 31, 2011

Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling.

scientific article

Hyperthermia in oncology

scientific article

Hyperthermia in oncology--a need for centers with competence and standards ⬇️

scientific article published on September 26, 2003

Hyperthermia: current status and therapeutic results ⬇️

scientific article published on September 26, 2003

Ifosfamide with regional hyperthermia in soft-tissue sarcomas

scientific article published on January 2003

Ifosfamide, carboplatin and etoposide (ICE) as second-line regimen alone and in combination with regional hyperthermia is active in chemo-pre-treated advanced soft tissue sarcoma of adults

scientific article

In vitro characterization of phosphatidylglyceroglycerol-based thermosensitive liposomes with encapsulated 1H MR T1-shortening gadodiamide

scientific article

Loss of p16(INK4a) is associated with reduced patient survival in soft tissue tumours, and indicates a senescence barrier.

scientific article published on 19 April 2014

MRI-assisted thermometry for regional hyperthermia and interstitial laser thermotherapy

scientific article

Neo-adjuvant chemotherapy alone or with regional hyperthermia for soft-tissue sarcoma - Authors' reply.

scientific article published on 31 October 2017

Non-invasive temperature mapping using MRI: comparison of two methods based on chemical shift and T1-relaxation

scientific article

Non-ionic Gd-based MRI contrast agents are optimal for encapsulation into phosphatidyldiglycerol-based thermosensitive liposomes

scientific article

Predicting toxicities for patients with advanced gastrointestinal stromal tumours treated with imatinib: A study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Tria

article

Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

scientific article

Progressive natural killer cell dysfunction associated with alterations in subset proportions and receptor expression in soft-tissue sarcoma patients.

scientific article published on 29 April 2016

Regional Hyperthermia With Neoadjuvant Chemotherapy for Treatment of Soft Tissue Sarcoma-Reply

scientific article published on 01 January 2019

Regional hyperthermia for high-risk soft tissue sarcoma treatment: present status and next questions

scientific article

Regulation of Deoxycytidine Kinase by Deoxycytidine and Deoxycytidine 5′ Triphosphate in Whole Leukemia and Tumor Cells ⬇️

scientific article published on 01 January 1998

Size of thermosensitive liposomes influences content release

scientific article

Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Soft tissue sarcomas—what is currently being done ⬇️

scientific article published on October 1, 1995

Soft-tissue sarcoma: recent developments

scientific article published on 7 August 2012

Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report

scientific article published on 01 January 2020

The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death

scientific article

The role of heat shock proteins in the stimulation of an immune response

scientific article published on March 1, 1998

Topotecan plus cyclophosphamide in adults with relapsed or refractory pediatric-type sarcoma: a retrospective analysis from the German Sarcoma Medical Oncology Group (AIO).

scientific article published on 12 July 2015

VEGFR2 predicts decreased patients survival in soft tissue sarcomas.

scientific article published on 21 May 2015

Validation of MR thermometry technology: a small animal model for hyperthermic treatment of tumours

scientific article

[Operative therapy of abdominal and retroperitoneal sarcoma]

scientific article published on 01 May 2014

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