List of works - K P Williams

Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells

scientific article

Data on peptides identified by mass spectrometry analysis of in vitro DYRK1A-mediated phosphorylation sites on GLI1.

scientific article

Design and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.

scientific article

Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS).

scientific article

Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

scientific article

Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening

scientific article

Genetic vulnerabilities to prenatal alcohol exposure: Limb defects in sonic hedgehog and GLI2 heterozygous mice.

scientific article published on 15 May 2017

Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1.

scientific article

Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies

scientific article

Maximizing binding capacity for protein A chromatography.

scientific article published on 2 September 2014

Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.

scientific article

Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice.

scientific article

Quantitative high-throughput efficacy profiling of approved oncology drugs in inflammatory breast cancer models of acquired drug resistance and re-sensitization ⬇️

scientific article published on May 17, 2013

Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells ⬇️

scientific article published on September 7, 2010

Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target

scientific article published on 11 May 2018

Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.

scientific article

Validating Identity, Mass Purity and Enzymatic Purity of Enzyme Preparations ⬇️

scientific article published on January 1, 2004

List of works by K P Williams

Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells

Data on peptides identified by mass spectrometry analysis of in vitro DYRK1A-mediated phosphorylation sites on GLI1.

Design and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.

Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS).

Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening

Genetic vulnerabilities to prenatal alcohol exposure: Limb defects in sonic hedgehog and GLI2 heterozygous mice.

Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1.

Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies

Maximizing binding capacity for protein A chromatography.

Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.

Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice.

Quantitative high-throughput efficacy profiling of approved oncology drugs in inflammatory breast cancer models of acquired drug resistance and re-sensitization ⬇️

Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells ⬇️

Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target

Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.

Validating Identity, Mass Purity and Enzymatic Purity of Enzyme Preparations ⬇️