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List of works by Francesco Sassi

A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy.

scientific article published on 3 October 2017

A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.

scientific article published on 30 May 2011

Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models

scientific article

Cytokine-Induced Killer Cells Kill Chemo-surviving Melanoma Cancer Stem Cells.

scientific article published on 4 November 2016

Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas.

scientific article published on 19 December 2013

Different role of COX-2 and angiogenesis in canine inflammatory and non-inflammatory mammary cancer ⬇️

scientific article published on March 11, 2013

Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer

scientific article

Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

scientific article published in January 2015

Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic Correlations

article

Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy.

scientific article

IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.

scientific article published on January 2015

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity

scientific article published on 5 May 2016

MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors.

scientific article

Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.

scientific article

Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis.

scientific article published on 14 January 2013

Modeling tumor progression by the sequential introduction of genetic alterations into the genome of human normal cells.

scientific article

Molecular Pathways: Sensitivity and Resistance to Anti-EGFR Antibodies.

scientific article published on 12 June 2015

Morphology of the myoepithelial cell: immunohistochemical characterization from resting to motile phase

scientific article published on 05 August 2012

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma.

scientific article published on 13 July 2016

Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens

scientific article published on 10 April 2019

Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts.

scientific article published on 22 March 2018

Screening for the FIG-ROS1 fusion in biliary tract carcinomas by nested PCR.

scientific article published on 18 September 2014

Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas.

scientific article published on 21 August 2015

Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.

scientific article

The genomic landscape of response to EGFR blockade in colorectal cancer.

scientific article published on 30 September 2015

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