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List of works by Mark Prausnitz

A Microneedle Patch for Measles and Rubella Vaccination Is Immunogenic and Protective in Infant Rhesus Macaques.

scientific article published on 26 April 2018

A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines.

scientific article published on 19 June 2017

A microneedle patch containing measles vaccine is immunogenic in non-human primates

scientific article

A microneedle patch for measles and rubella vaccination: a game changer for achieving elimination

scientific article published on 01 July 2020

A microneedle roller for transdermal drug delivery

scientific article published on 17 July 2010

A peptide chaperone for transdermal drug delivery

scientific article published on 01 April 2006

A protective role of murine langerin⁺ cells in immune responses to cutaneous vaccination with microneedle patches

scientific article

A quantitative study of electroporation showing a plateau in net molecular transport ⬇️

scientific article published on July 1, 1993

Acceptability of an inactivated influenza vaccine delivered by microneedle patch: Results from a phase I clinical trial of safety, reactogenicity, and immunogenicity

scientific article published on 10 August 2020

An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine.

scientific article

An electrically active microneedle array for electroporation

scientific article

Analysis of Mechanical Failure of Polymer Microneedles by Axial Force

scientific article

Assessment of trueness of a glucose monitor using interstitial fluid and whole blood as specimen matrix

scientific article published in February 2006

Bacillus Calmette-Guérin vaccination using a microneedle patch.

scientific article

Biochemical enhancement of transdermal delivery with magainin peptide: modification of electrostatic interactions by changing pH.

scientific article published on 13 June 2008

Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery

scientific article published in April 2005

Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery.

scientific article published in January 2004

Bioeffects caused by changes in acoustic cavitation bubble density and cell concentration: a unified explanation based on cell-to-bubble ratio and blast radius

scientific article published in August 2003

Can ultrasound enable efficient intracellular uptake of molecules? A retrospective literature review and analysis

scientific article

Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes.

scientific article published on 13 February 2017

Changes in cell morphology due to plasma membrane wounding by acoustic cavitation

scientific article

Circumferential flow of particles in the suprachoroidal space is impeded by the posterior ciliary arteries.

scientific article published on 11 March 2016

Clearance Kinetics and Clearance Routes of Molecules From the Suprachoroidal Space After Microneedle Injection

scientific article published on January 2017

Co-Delivery of M2e Virus-Like Particles with Influenza Split Vaccine to the Skin Using Microneedles Enhances the Efficacy of Cross Protection.

scientific article published on 18 April 2019

Coated microneedles for drug delivery to the eye.

scientific article published in September 2007

Coated microneedles for transdermal delivery

scientific article (publication date: 12 February 2007)

Coating formulations for microneedles

scientific article

Collagenase injection into the suprachoroidal space of the eye to expand drug delivery coverage and increase posterior drug targeting

scientific article published on 01 October 2019

Collection of analytes from microneedle patches

scientific article

Cross-protection by co-immunization with influenza hemagglutinin DNA and inactivated virus vaccine using coated microneedles.

scientific article

Current status and future potential of transdermal drug delivery

scientific article (publication date: February 2004)

Cutaneous vaccination ameliorates Zika virus-induced neuro-ocular pathology via reduction of anti-ganglioside antibodies

scientific article published on 06 August 2020

DNA uptake, intracellular trafficking and gene transfection after ultrasound exposure.

scientific article published on 7 May 2016

DNA vaccination in the skin using microneedles improves protection against influenza

scientific article

Delivery Systems for Intradermal Vaccination ⬇️

scientific article published on January 1, 2012

Delivery of molecules into cells using carbon nanoparticles activated by femtosecond laser pulses

scientific article

Delivery of salmon calcitonin using a microneedle patch

scientific article published on 8 December 2011

Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles

scientific article

Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection

scientific article published on 12 April 2012

Development of a thermostable microneedle patch for influenza vaccination

scientific article published in December 2014

Development of a thermostable microneedle patch for polio vaccination

article

Dihydroergotamine mesylate-loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapy

scientific article published on 16 October 2017

Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks

scientific article published in 2021

Dissolving microneedle patch for transdermal delivery of human growth hormone

scientific article

Dissolving microneedles for transdermal drug delivery

scientific article published on 7 February 2008

Dissolving polymer microneedle patches for influenza vaccination

scientific article

Distribution of particles, small molecules and polymeric formulation excipients in the suprachoroidal space after microneedle injection.

scientific article published on 11 October 2016

Does needle size matter?

scientific article published on September 2007

Dose sparing and enhanced immunogenicity of inactivated rotavirus vaccine administered by skin vaccination using a microneedle patch

scientific article

Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles

scientific article

Drug delivery through the sclera: effects of thickness, hydration, and sustained release systems

scientific article published in March 2004

Drug delivery using microneedle patches: not just for skin

scientific article published on 07 May 2018

Drug delivery: Puncturing cells en masse.

scientific article published in May 2015

Ebola Vaccination Using a DNA Vaccine Coated on PLGA-PLL/γPGA Nanoparticles Administered Using a Microneedle Patch

scientific article

Editorial

Effect of Osmotic Pressure on the Stability of Whole Inactivated Influenza Vaccine for Coating on Microneedles.

scientific article published on 31 July 2015

Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine

scientific article (publication date: 2012)

Effect of laser fluence, nanoparticle concentration and total energy input per cell on photoporation of cells

scientific article published on 30 April 2018

Effect of microneedle design on pain in human volunteers

scientific article

Effects of General Anesthesia on Intraocular Pressure in Rabbits

scientific article published on 28 September 2020

Efficient intracellular delivery of molecules with high cell viability using nanosecond-pulsed laser-activated carbon nanoparticles

scientific article

Electrical impedance spectroscopy for rapid and noninvasive analysis of skin electroporation.

scientific article

Electroporation-mediated delivery of molecules to model intestinal epithelia

scientific article published on February 2004

Electrospun Transdermal Patch for Contraceptive Hormone Delivery

scientific article published on 01 January 2019

Enabling skin vaccination using new delivery technologies

scientific article

Energy Transfer Mechanisms during Molecular Delivery to Cells by Laser-Activated Carbon Nanoparticles

scientific article

Engineering Microneedle Patches for Vaccination and Drug Delivery to Skin

scientific article published on 24 March 2017

Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch

article

Enhanced Stability of Inactivated Influenza Vaccine Encapsulated in Dissolving Microneedle Patches.

scientific article published on December 2015

Enhanced immune responses by skin vaccination with influenza subunit vaccine in young hosts.

scientific article published on 2 March 2015

Enhanced memory responses to seasonal H1N1 influenza vaccination of the skin with the use of vaccine-coated microneedles

scientific article

Equilibrium loading of cells with macromolecules by ultrasound: effects of molecular size and acoustic energy

scientific article

Extended delivery of vaccines to the skin improves immune responses.

article

Fabrication of dissolving polymer microneedles for controlled drug encapsulation and delivery: Bubble and pedestal microneedle designs

scientific article published on October 2010

Faster pharmacokinetics and increased patient acceptance of intradermal insulin delivery using a single hollow microneedle in children and adolescents with type 1 diabetes

scientific article

Feasibility of Hepatitis B Vaccination by Microneedle Patch: Cellular and Humoral Immunity Studies in Rhesus Macaques

scientific article published on 01 November 2019

Flux across [corrected] microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro

scientific article published on May 2008

Formulation and coating of microneedles with inactivated influenza virus to improve vaccine stability and immunogenicity

scientific article

Formulation of microneedles coated with influenza virus-like particle vaccine.

scientific article

Formulation to target delivery to the ciliary body and choroid via the suprachoroidal space of the eye using microneedles

scientific article

Future directions for therapeutic ultrasound

scientific article published in April 2007

Gene packaging with lipids, peptides and viruses inhibits transfection by electroporation in vitro

scientific article published on 01 January 2003

Gene transfection enhanced by ultrasound exposure combined with drug treatment guided by gene chip analysis

scientific article

Hepatitis B vaccination using a dissolvable microneedle patch is immunogenic in mice and rhesus macaques

scientific article published on 27 August 2018

Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice

article published in the Proceedings of the National Academy of Sciences of the United States of America

Hollow metal microneedles for insulin delivery to diabetic rats

scientific article

Hollow microneedles for intradermal injection fabricated by sacrificial micromolding and selective electrodeposition

scientific article

Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics.

scientific article published on 9 February 2018

Immune stimulation following microneedle delivery of influenza virus-like particle (VLP) vaccines to human skin

Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge

scientific article

Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial

scientific article

Improved immunogenicity of individual influenza vaccine components delivered with a novel dissolving microneedle patch stable at room temperature

scientific article

Improved influenza vaccination in the skin using vaccine coated microneedles

scientific article published on 15 September 2009

Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles

scientific article

Improving patient acceptance of insulin therapy by improving needle design

scientific article

Inactivated polio vaccination using a microneedle patch is immunogenic in the rhesus macaque.

scientific article

Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice.

scientific article published on 12 January 2018

Increased immunogenicity of avian influenza DNA vaccine delivered to the skin using a microneedle patch.

scientific article

Increased permeability of intestinal epithelial monolayers mediated by electroporation

scientific article published on 18 December 2004

Individually coated microneedles for co-delivery of multiple compounds with different properties

scientific article published on 01 October 2018

Influence of the cell wall on intracellular delivery to algal cells by electroporation and sonication

scientific article

Influenza immunization with trehalose-stabilized virus-like particle vaccine using microneedles

scientific article

Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin.

scientific article

Infusion pressure and pain during microneedle injection into skin of human subjects

scientific article

Inkjet printing of transdermal microneedles for the delivery of anticancer agents.

scientific article published on 21 January 2015

Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force

scientific article published in August 2004

Intracellular delivery of molecules using microfabricated nanoneedle arrays.

scientific article published on February 2016

Intracellular protein delivery and gene transfection by electroporation using a microneedle electrode array

scientific article

Intradermal Vaccination With Adjuvanted Ebola Virus Soluble Glycoprotein Subunit Vaccine by Microneedle Patches Protects Mice Against Lethal Ebola Virus Challenge

scientific article published on 01 November 2018

Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge

scientific article published in Scientific Reports

Intradermal vaccination with influenza virus-like particles by using microneedles induces protection superior to that with intramuscular immunization

scientific article

Intrascleral drug delivery to the eye using hollow microneedles

scientific article

Intrastromal delivery of bevacizumab using microneedles to treat corneal neovascularization

scientific article

Kinetics of skin resealing after insertion of microneedles in human subjects

scientific article

Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin

scientific article

Local response to microneedle-based influenza immunization in the skin.

scientific article published on 6 March 2012

Local transdermal delivery of phenylephrine to the anal sphincter muscle using microneedles.

scientific article

Long-acting reversible contraception by effervescent microneedle patch

scientific article published on 06 November 2019

Long-term protective immunity from an influenza virus-like particle vaccine administered with a microneedle patch.

scientific article published on 17 July 2013

Long-term stability of influenza vaccine in a dissolving microneedle patch.

scientific article published on 29 February 2016

Measles vaccination using a microneedle patch

scientific article published on 05 October 2012

Measurement and correlation of acoustic cavitation with cellular bioeffects

scientific article published on July 2006

Measurement and prediction of lateral diffusion within human sclera

scientific article published in July 2006

Measurement of rapid release kinetics for drug delivery

scientific article published on April 1, 1995

Mechanism of fluid infusion during microneedle insertion and retraction

scientific article published on 19 April 2006

Mechanism of intracellular delivery by acoustic cavitation

scientific article published in June 2006

Mechanisms of sampling interstitial fluid from skin using a microneedle patch

scientific article published on 16 April 2018

Mechanistic studies of skin electroporation using biophysical methods

scientific article published on 01 January 2000

Membrane disruption by optically controlled microbubble cavitation

Micro-scale devices for transdermal drug delivery

scientific article

Microchip for sustained drug delivery by diffusion through microchannels

scientific article published on 4 January 2012

Microelectronic control of drug delivery

scientific article published on July 2012

Microfabricated Microneedles: A Novel Approach to Transdermal Drug Delivery ⬇️

scientific article published on 01 August 1998

Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies

scientific article

Microinfusion using hollow microneedles

scientific article published in January 2006

Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-cell responses in mice

scientific article

Microneedle delivery of an M2e-TLR5 ligand fusion protein to skin confers broadly cross-protective influenza immunity

scientific article

Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring.

scientific article

Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection.

scientific article published on 21 May 2015

Microneedle patch drug delivery in the gut

scientific article published on 01 October 2019

Microneedle patches for vaccination in developing countries.

scientific article

Microneedle patches: usability and acceptability for self-vaccination against influenza

scientific article

Microneedle vaccination with stabilized recombinant influenza virus hemagglutinin induces improved protective immunity

scientific article

Microneedle-based vaccines

scientific article

Microneedles for drug and vaccine delivery

scientific article

Microneedles for transdermal drug delivery

scientific article published on March 2004

Microneedles permit transdermal delivery of a skin-impermeant medication to humans

scholarly article

Microsecond thermal ablation of skin for transdermal drug delivery

scientific article

Minimally invasive extraction of dermal interstitial fluid for glucose monitoring using microneedles

scientific article published in February 2005

Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedles

scientific article published on June 2009

Minimally invasive protein delivery with rapidly dissolving polymer microneedles

scientific article

Model of transient drug diffusion across cornea.

scientific article

Modeling transmembrane transport through cell membrane wounds created by acoustic cavitation

scientific article

Monitoring drug pharmacokinetics and immunologic biomarkers in dermal interstitial fluid using a microneedle patch

scientific article published on 06 February 2019

Mucoadhesive Microparticles Engineered for Ophthalmic Drug Delivery

scientific article

Mucoadhesive microdiscs engineered for ophthalmic drug delivery: effect of particle geometry and formulation on preocular residence time

scientific article

Mucoadhesive microparticles in a rapidly dissolving tablet for sustained drug delivery to the eye

scientific article

Non-invasive assessment and control of ultrasound-mediated membrane permeabilization

scientific article published on June 1, 1998

Ocular delivery of macromolecules

scientific article

Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle.

scientific article published on 2 March 2018

Optimization of microdermabrasion for controlled removal of stratum corneum

scientific article

Optimization of transdermal delivery using magainin pore-forming peptide

scientific article

Parameters affecting intracellular delivery of molecules using laser-activated carbon nanoparticles

scientific article published on 6 January 2016

Particle-stabilized emulsion droplets for gravity-mediated targeting in the posterior segment of the eye

scientific article

Pharmaceutical jewelry: Earring patch for transdermal delivery of contraceptive hormone

scientific article published on 12 March 2019

Photoporation Using Carbon Nanotubes for Intracellular Delivery of Molecules and Its Relationship to Photoacoustic Pressure

scientific article published on 4 December 2017

Physical parameters influencing optimization of ultrasound-mediated DNA transfection

scientific article published in April 2004

Plasmid DNA and siRNA transfection of intestinal epithelial monolayers by electroporation

scientific article published on 6 March 2006

Plasmonic Paper Microneedle Patch for On-Patch Detection of Molecules in Dermal Interstitial Fluid

scientific article published on 22 May 2019

Pocketed Microneedles for Drug Delivery to the Skin

scientific article

Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin ⬇️

scientific article published on November 23, 2012

Poloxamer surfactant preserves cell viability during photoacoustic delivery of molecules into cells

scientific article

Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization.

scientific article published on 28 October 2009

Polymer microneedles for controlled-release drug delivery.

scientific article

Polymer particle-based micromolding to fabricate novel microstructures

scientific article published in April 2007

Precise microinjection into skin using hollow microneedles

scientific article published in May 2006

Prediction of ultrasound-mediated disruption of cell membranes using machine learning techniques and statistical analysis of acoustic spectra.

scientific article

Quantification of optison bubble size and lifetime during sonication dominant role of secondary cavitation bubbles causing acoustic bioeffects

scientific article published on April 2004

Rabies vaccination in dogs using a dissolving microneedle patch.

scientific article published on 11 August 2016

Rapid local anesthesia in humans using minimally invasive microneedles

scientific article

Rapid pharmacokinetics of intradermal insulin administered using microneedles in type 1 diabetes subjects

scientific article

Rapid release of plasmid DNA from surfaces coated with polyelectrolyte multilayers promoted by the application of electrochemical potentials

scientific article

Rapidly separable microneedle patch for the sustained release of a contraceptive

scientific article published on 14 January 2019

Recovery of skin barrier after stratum corneum removal by microdermabrasion

scientific article published on 19 October 2011

Recovery of skin barrier properties after sonication in human subjects

scientific article published on 21 June 2009

Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch

scientific article published on 04 January 2019

Reliability and accuracy of intradermal injection by Mantoux technique, hypodermic needle adapter, and hollow microneedle in pigs.

scientific article published in April 2014

Reversible skin permeabilization for transdermal delivery of macromolecules

scientific article published on January 1, 1997

Role of cytoskeletal mechanics and cell membrane fluidity in the intracellular delivery of molecules mediated by laser-activated carbon nanoparticles.

scientific article

STAR particles for enhanced topical drug and vaccine delivery

scientific article published on 09 March 2020

Sampling interstitial fluid from human skin using a microneedle patch

scientific article published on 01 November 2020

Selective removal of stratum corneum by microdermabrasion to increase skin permeability.

scientific article published on 25 June 2009

Self-healing encapsulation and controlled release of vaccine antigens from PLGA microparticles delivered by microneedle patches.

scientific article

Separable arrowhead microneedles

scientific article

Serological memory and long-term protection to novel H1N1 influenza virus after skin vaccination

scientific article

Shear-induced intracellular loading of cells with molecules by controlled microfluidics

scientific article

Skin immunization by microneedle patch overcomes statin-induced suppression of immune responses to influenza vaccine

scientific article published on 19 December 2017

Skin pretreatment with microneedles prior to pilocarpine iontophoresis increases sweat production

scientific article

Stability kinetics of influenza vaccine coated onto microneedles during drying and storage.

scientific article

Stability of influenza vaccine coated onto microneedles

scientific article published on 21 February 2012

Stability of whole inactivated influenza virus vaccine during coating onto metal microneedles

scientific article published on 13 December 2012

Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin

scientific article

Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza.

scientific article published on 26 February 2018

Suprachoroidal drug delivery to the back of the eye using hollow microneedles

scientific article

Sustained scleral stiffening in rats after a single genipin treatment

scientific article published on 16 October 2019

Synergistic effect of ultrasound and PEI on DNA transfection in vitro

scientific article

Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol

scientific article

Tapered conical polymer microneedles fabricated using an integrated lens technique for transdermal drug delivery

scientific article published in May 2007

Targeted Drug Delivery Within the Eye Through the Suprachoroidal Space.

scientific article published on 16 November 2016

Targeted Drug Delivery in the Suprachoroidal Space by Swollen Hydrogel Pushing.

scientific article

Targeted administration into the suprachoroidal space using a microneedle for drug delivery to the posterior segment of the eye

scientific article

Targeted delivery of antiglaucoma drugs to the supraciliary space using microneedles

scientific article

Targeting drug delivery within the suprachoroidal space

scientific article published on 03 April 2019

Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy.

scientific article published on 17 June 2016

The effect of heat on skin permeability

scientific article published on 29 March 2008

The rule of five for non-oral routes of drug delivery: ophthalmic, inhalation and transdermal

scientific article

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial.

scientific article published on 27 June 2017

The suprachoroidal space as a route of administration to the posterior segment of the eye

scientific article published on 01 February 2018

Thickness and Closure Kinetics of the Suprachoroidal Space Following Microneedle Injection of Liquid Formulations.

scientific article published on January 2017

Tissue electroporation: quantification and analysis of heterogeneous transport in multicellular environments

scientific article

Tolerability, usability and acceptability of dissolving microneedle patch administration in human subjects

scientific article published on 2 March 2017

Transdermal Delivery of Heparin by Skin Electroporation ⬇️

scientific article published on 01 November 1995

Transdermal delivery enhanced by antimicrobial peptides

scientific article published on October 2010

Transdermal delivery enhanced by magainin pore-forming peptide

scientific article

Transdermal delivery of insulin using microneedles in vivo

scientific article

Transdermal delivery of molecules is limited by full epidermis, not just stratum corneum

scientific article published on 30 November 2012

Transdermal delivery of naltrexol and skin permeability lifetime after microneedle treatment in hairless guinea pigs

scientific article

Transdermal drug delivery

scientific article

Transdermal influenza immunization with vaccine-coated microneedle arrays

scientific article

Transdermal insulin delivery using microdermabrasion

scientific article

Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity

scientific article published on 05 November 2020

Ultrasonically targeted delivery into endothelial and smooth muscle cells in ex vivo arteries

scientific article

Ultrasound-enhanced chemotherapy and gene delivery for glioma cells

scientific article published in October 2007

Ultrasound-enhanced drug transport and distribution in the brain

scientific article

Using retinal function to define ischemic exclusion criteria for animal models of glaucoma

scientific article published on 07 November 2020

Vaccination by microneedle patch with inactivated respiratory syncytial virus and monophosphoryl lipid A enhances the protective efficacy and diminishes inflammatory disease after challenge

scientific article published in PLoS ONE

Vaccination with human papillomavirus pseudovirus-encapsidated plasmids targeted to skin using microneedles

scientific article

Visualization of plasmid delivery to keratinocytes in mouse and human epidermis

scientific article published on 15 November 2011

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