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List of works by Janeen Trembley

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

scientific article

CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells

scientific article published on 02 April 2019

CDK11 complexes promote pre-mRNA splicing

scientific article

CK2 Molecular Targeting-Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer.

scientific article published on 21 February 2017

CK2 Pro-Survival Role in Prostate Cancer Is Mediated via Maintenance and Promotion of Androgen Receptor and NFκB p65 Expression

scientific article published on 14 June 2019

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors.

scientific article published on 20 August 2016

Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.

scientific article

Emergence of protein kinase CK2 as a key target in cancer therapy

scientific article

Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats

scientific article published in August 2017

Examination of CK2α and NF-κB p65 expression in human benign prostatic hyperplasia and prostate cancer tissues

scientific article published on 19 July 2016

Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways

scientific article published on 15 March 2016

Gulf War Illness-associated increases in blood levels of interleukin 6 and C-reactive protein: biomarker evidence of inflammation

scientific article published on 18 December 2019

Improving Health Care for Veterans With Gulf War Illness

article

Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma.

scientific article

Molecular Regulation of Liver Regenerationa ⬇️

scientific article published on December 31, 1997

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

scientific article published on 12 October 2011

Posttranscriptional regulation of cyclin B messenger RNA expression in the regenerating rat liver

scientific journal article

Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

scientific article

Protein kinase CK2 impact on intracellular calcium homeostasis in prostate cancer

scientific article published on 20 May 2020

Protein kinase CK2 in health and disease: CK2: a key player in cancer biology

scientific article

Protein kinase CK2 inhibition induces cell death via early impact on mitochondrial function.

scientific article

Role of CDK/cyclin complexes in transcription and RNA splicing

scientific article

Tenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in mice

scientific article

The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing ⬇️

scientific article published on November 2, 2010

The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinase in vivo

scientific article

Therapeutic Targeting of Protein Kinase CK2 Gene Expression in Feline Oral Squamous Cell Carcinoma: A Naturally Occurring Large-Animal Model of Head and Neck Cancer

scientific article published on 23 March 2017

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