List of works - Eija Pirinen

ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

scientific article

Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.

scientific article published on 27 February 2017

Adipose tissue mitochondrial capacity associates with long-term weight loss success

scientific article published on 5 December 2017

Animal disease models generated by genetic engineering of polyamine metabolism.

scientific article

Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults

scientific article published on 25 June 2010

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

scientific article

Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus.

scientific article

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

scientific article published on 7 September 2017

Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

scientific article published on 12 September 2019

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice.

scientific article published on 29 August 2014

Mice with targeted disruption of spermidine/spermine N-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging

scientific article published in October 2006

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

scientific article

NAD+ repletion produces no therapeutic effect in mice with respiratory chain complex III deficiency and chronic energy deprivation

scientific article published on 21 May 2018

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

scientific article

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

article

Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.

scientific article published on 17 November 2015

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

scientific article

Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis.

scientific article published on 10 June 2014

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.

scientific article

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

scientific article published on June 2012

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

scientific article published on 01 March 2019

Transgenic rodents with altered SSAT expression as models of pancreatitis and altered glucose and lipid metabolism.

scientific article published in January 2011

Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.

scientific article published on 13 January 2016

List of works by Eija Pirinen

ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.

Adipose tissue mitochondrial capacity associates with long-term weight loss success

Animal disease models generated by genetic engineering of polyamine metabolism.

Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus.

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice.

Mice with targeted disruption of spermidine/spermine N-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

NAD+ repletion produces no therapeutic effect in mice with respiratory chain complex III deficiency and chronic energy deprivation

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis.

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

Transgenic rodents with altered SSAT expression as models of pancreatitis and altered glucose and lipid metabolism.

Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.