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List of works by Ellen F Carney

A link between mitochondrial dysfunction and innate immune activation in FSGS

scientific article published on 01 December 2018

A novel RNA interference approach to targeting sFLT1 in pre-eclampsia

scientific article published on 01 February 2019

A novel SGLT1-mediated mechanism of hyperglycaemia-induced hyperfiltration

scientific article published on 01 July 2019

A novel approach to targeting TGFβ1

scientific article published on 01 December 2019

AAV encompasses two major genetically distinct conditions with different autoantibody specificities ⬇️

scientific article published on 07 August 2012

ABCF1 switches off inflammation in sepsis

scientific article published on 01 May 2019

AHR activation by uraemic solutes

scientific article published on 01 February 2020

APOL1 risk variants induce opening of the mitochondrial permeability transition pore

scientific article published on 01 December 2019

Acute coronary syndromes: management of acute coronary syndrome-renal outcomes

scientific article published on 23 July 2013

Acute kidney injury. Protective role of gut microbial SCFAs.

scientific article published on 3 February 2015

Acute kidney injury: Fenoldopam infusion does not reduce the need for RRT in patients with AKI after cardiac surgery

scientific article published on 14 October 2014

Acute kidney injury: High-potency statin therapy and risk of acute kidney injury.

scientific article published on 9 April 2013

Acute kidney injury: Proximal tubule cells modulate inflammation after renal injury

scientific article published on 31 March 2015

Acute kidney injury: Role of platelet activation and NETs in renal IRI

scientific article published on 17 October 2016

Acute kidney injury: Targeting Treg cells to protect the kidney

scientific article published on 12 June 2017

Acute kidney injury: critical role of complement in EndMT.

scientific article

Adoptive transfer of tolerized dendritic cells—a potential new strategy for the prevention of AKI ⬇️

scientific article published on November 13, 2012

Altered ammonia metabolism in ccRCC

scientific article published on 01 August 2018

An autoimmune mechanism may underlie most cases of primary MPGN and C3G

scientific article published on 01 April 2020

Antiplatelet therapy: Can cangrelor bridge the gap to cardiac surgery?

scientific article published on 07 February 2012

Atrial fibrillation: Risk of bleeding with dabigatran versus warfarin particularly high in CKD

scientific article published on 25 November 2014

Augmenting NAD+ may combat kidney stress

scientific article published on 01 November 2018

Autoimmunity: AAV encompasses two major genetically distinct conditions with different autoantibody specificities

scientific article published on 07 August 2012

Autoimmunity: HLA-mediated protection in Goodpasture disease

scientific article published on 15 May 2017

Autoimmunity: HLA-mediated protection in Goodpasture disease

scientific article published on 18 May 2017

Autoimmunity: IL-17C promotes immune-mediated glomerular disease

scientific article published on 19 March 2018

Autoimmunity: SLE autoantibodies have lethal neurotoxic effects in female foetuses.

scientific article published on 22 May 2012

Basic research: Bioengineering the kidney microvasculature

scientific article published on 30 December 2015

Basic research: Critical role of mTORC1 in tubular cells.

scientific article

CDKL5 controls RTEC fate during AKI

scientific article published on 13 May 2020

CXCL12 limits podocyte regeneration

scientific article published on 01 January 2019

Cardiovascular disease: Warfarin might be beneficial in nondialysis-dependent patients with CKD and atrial fibrillation

scientific article published on 18 March 2014

Cell biology: Intercellular communication in the kidney

scientific article published on 12 April 2016

Cell biology: Vasopressin-independent AQP2 trafficking.

scientific article published in August 2016

Chronic kidney disease. Walking reduces inflammation in predialysis CKD

scientific article published on 22 April 2014

Chronic kidney disease: FGF-23 inhibits neutrophil activation

scientific article published on 29 February 2016

Chronic kidney disease: Key role of exosomes in albumin-induced inflammation

scientific article

Chronic kidney disease: Mechanisms of APOL1-associated renal disease

scientific article published on 05 December 2016

Chronic kidney disease: Microbiota trigger inflammation

scientific article published on 23 May 2016

Chronic kidney disease: PLD4 regulates kidney fibrosis.

scientific article published on 4 September 2017

Chronic kidney disease: Paradoxical association between serum IL-10 levels and risk of cardiovascular events

scientific article published on 20 May 2014

Chronic kidney disease: Procoagulant microparticles provide a novel pathogenic link between hyperphosphataemia and cardiovascular risk

scientific article published on 24 March 2015

Chronic kidney disease: Renal adenosine in hypertensive CKD.

scientific article published on 30 April 2013

Chronic kidney disease: Role of suPAR in APOL1-associated kidney disease

scientific article published on 03 July 2017

Chronic kidney disease: Skin sodium linked to left ventricular hypertrophy

scientific article published on 27 February 2017

Circadian rhythms: Functional roles of the renal tubular circadian clock.

scientific article

Classical ataxia telangiectasia patients have a congenitally aged immune system with high expression of CD95.

scientific article published on 30 May 2012

Clinical trial: Lack of benefit of MMF in IgAN

scientific article published on 11 August 2015

Clinical trials. Renal safety of TDF as pre-exposure prophylaxis for HIV-1 infection.

scientific article published on 20 January 2015

Cortical bone loss in patients with chronic kidney disease ⬇️

scientific article published on March 19, 2013

Cystic kidney disease: Intracellular clusterin implicated in nephropathic cystinosis

scientific article published on 12 August 2014

Development: Fetal growth and renal outcomes

scientific article published on 27 May 2014

Development: Wnt5a implicated in CAKUT.

scientific article published on 19 August 2014

Development: Wnt5a implicated in CAKUT.

scientific article published on 26 August 2014

Diabetic nephropathy: MiR-23b protects against fibrosis in diabetic nephropathy.

scientific article

Diabetic nephropathy: Renoprotective effects of angiotensin 1-7

scientific article published on 11 March 2014

Diabetic nephropathy: Restoring podocyte proteostasis in DN.

scientific article

Diabetic nephropathy: Role of podocyte SHP-1 in hyperglycaemic memory.

scientific article published on 19 September 2016

Diabetic nephropathy: The genetic architecture of DKD in T1DM.

scientific article

Diabetic nephropathy: cholesterol and podocyte injury.

scientific article published on 30 July 2013

Dialysis: Efficacy of catheter lock solutions

scientific article published on 5 November 2013

Dialysis: Efficacy of tenapanor in hyperphosphataemia

scientific article published on 27 February 2017

Dialysis: Prevention of peritoneal-dialysis-related infections-antibacterial honey might not be the solution

scientific article published on 22 October 2013

Dialysis: optimal timing of arteriovenous fistula placement in elderly patients

scientific article published on 16 September 2014

Dietary modification of gut microbial metabolism protects the kidney

scientific article published on 06 October 2020

Empagliflozin improves kidney outcomes in patients with heart failure and CKD

scientific article published on 10 November 2020

Endocytosis in the proximal tubule

scientific article published on 01 January 2019

Epidemiology: Global Burden of Disease Study 2013 reports that disability caused by CKD is increasing worldwide

scientific article published on 23 June 2015

Epidemiology: Paediatric acute kidney injury

scientific article

Epigenetics: Disturbed imprinting in pre-eclampsia.

scientific article

Fibrosis: GLI2 inhibition reduces myofibroblast generation and kidney fibrosis

scientific article published on 4 August 2015

GATM mutations cause mitochondrial abnormalities and kidney failure

scientific article published on 01 July 2018

Genetics: Evolving risks of UMOD variants

scientific article published on 30 March 2016

Genetics: Increased prevalence of large genomic imbalances among children with chronic kidney disease

scientific article published on 05 May 2015

Genetics: Mapping pathways of CKD

scientific article published on 01 July 2014

Genetics: SGPL1 mutations cause a novel SRNS syndrome.

scientific article published on 20 February 2017

Glomerular disease. Antiproteinuric efficacy of A. manihot superior to losartan

scientific article published on 8 April 2014

Glomerular disease: Addition of immunosuppression to supportive care does not STOP-IgAN

scientific article published on 21 December 2015

Glomerular disease: Albuminuria inhibits podocyte regeneration

scientific article published on 03 September 2013

Glomerular disease: Functional consequences of C5 nephritic factors in C3 glomerulopathies

scientific article published on 31 July 2017

Glomerular disease: Protective role of TGR5 activation

scientific article published on 20 October 2015

Glomerular disease: Role of tonsillar B cells in IgAN

scientific article published on 19 December 2016

Glomerular disease: association of FSGS histologic variants with patient outcomes

scientific article published on 08 January 2013

Glomerular disease: autophagy failure and mitochondrial dysfunction in FSGS

scientific article published on 09 December 2014

Glomerular disease: frequency of podocyte-related gene mutations in FSGS

scientific article published on 25 February 2014

Glomerular diseases: Regulation of IgA production by TBK1 prevents nephropathy

scientific article published on 16 October 2012

Glomerular filtration rate: CKD risk factors are associated with increased single-nephron GFR

scientific article published on 26 June 2017

Hypertension: A new therapeutic strategy for PAH.

scientific article published on 30 June 2015

Hypertension: New non-RAS peptide modulates the vasoregulatory effects of angiotensin II

scientific article published on 14 April 2015

Hypertension: Regulation of salt appetite and blood pressure

scientific article published on 21 March 2016

Hypertension: Role of ARHGAP42 in hypertension

scientific article published on 06 February 2017

Hypertension: Role of C3aR and C5aR in Treg cells

scientific article published on 26 February 2018

Hypertension: Role of p66Shc in renal vascular dysfunction.

scientific article published on 20 June 2016

Hypertension: Role of γδ T cells in the development of hypertension

scientific article published on 10 April 2017

Hypertension: Vascular type 1A angiotensin II receptors regulate renal blood flow and natriuresis

scientific article published on 28 April 2015

Hypertension: sFlt-1 removal seems to be beneficial in women with pre-eclampsia.

scientific article

Immunology: T-cell exhaustion limits immune reactivity and is associated with good prognosis in autoimmune disease

scientific article published on 14 July 2015

Immunology: T-cell exhaustion limits immune reactivity and is associated with good prognosis in autoimmune disease.

scientific article

Inflammation: Activated protein C inhibits inflammasome activation in IRI.

scientific article

Intu protects the kidney

scientific article published on 01 June 2018

Ketosis slows the progression of PKD

scientific article published on 01 January 2020

Kidney cancer: IMPRINT: no survival benefit of IMA901 in RCC

scientific article published on 17 October 2016

Lupus nephritis: B-cell ERα signalling promotes lupus development

scientific article published on 14 November 2016

Lupus nephritis: Cholesterol accumulation in DCs promotes autoimmunity

scientific article published on 22 May 2017

Lupus nephritis: Role of NLRP3 inflammasomes in podocyte injury

scientific article published on 12 June 2017

Metabolism: Energy-efficient transport in the kidney.

scientific article published on 13 June 2016

Mineral metabolism: Spironolactone and calcification

scientific article published on 29 January 2013

Modulation of IGF-1 might prevent osteoporosis ⬇️

scientific article published on July 10, 2012

Monoclonal antibody therapy lowers LDL-cholesterol levels ⬇️

scientific article published on April 10, 2012

Monocytosis, atherosclerosis and increased cardiovascular risk in mild renal dysfunction ⬇️

scientific article published on February 19, 2013

Nephrotic syndrome: Novel monogenic causes of Galloway-Mowat syndrome

scientific article

Netrin-1 expression in proximal tubular epithelial cells protects against kidney inflammation and injury ⬇️

scientific article published on October 23, 2012

No significant effect of cinacalcet on cardiovascular outcomes in patients undergoing dialysis—EVOLVE results ⬇️

scientific article published on November 20, 2012

Nutrition: Folic acid delays CKD progression

scientific article published on 12 September 2016

Onconephrology: New mouse model of clear cell renal cell carcinoma.

scientific article published on 12 June 2017

Osteopontin drives renal metabolic dysfunction in Alport syndrome

scientific article published on 01 June 2018

Overall safety of on-pump and off-pump CABG surgery is similar ⬇️

scientific article published on April 10, 2012

Paediatrics: CARPEDIEM--continuous renal replacement therapy for infants.

scientific article published on 10 June 2014

Pax proteins regulate urine concentration

scientific article published on 29 May 2020

Perioperative sodium bicarbonate infusion for prevention of acute kidney injury—no benefit and possible harm ⬇️

scientific article published on May 7, 2013

Peritoneal dialysis: Cognitive behavioural therapy might improve patient adherence to fluid restrictions

scientific article published on 17 December 2013

Pharmacokinetic modelling using linked organ chips

scientific article published on 01 April 2020

Pharmacology: NHERF3 regulates MRP4-mediated efflux of drug molecules in the kidneys

scientific article published on 04 February 2014

Pivotal role of CaMK4 in podocyte injury

scientific article published on 01 October 2018

Podocyte biology: Dynamic control of actin remodelling.

scientific article

Podocyte biology: Phosphorylation preserves podocytes

scientific article published on 29 February 2016

Podocytes: ShcA regulates nephrin turnover

scientific article published on 30 October 2017

Polycystic kidney disease: Cyst growth and cilia in ADPKD

scientific article published on 13 August 2013

Polycystic kidney disease: Macrophage migration inhibitory factor regulates cyst growth in ADPKD

scientific article published on 26 May 2015

Polycystic kidney disease: MicroRNA-17: a new drug target for ADPKD.

scientific article

Polycystic kidney disease: Modulation of cystogenesis by the microenviroment.

scientific article published on 16 October 2017

Polycystic kidney disease: PMM2 mutation causes PKD and hyperinsulinism.

scientific article published on 24 April 2017

Polycystic kidney disease: Role of TRPV4 in renal cystogenesis

scientific article published on 05 March 2013

Polycystic kidney disease: TGF-β signalling and vascular complications in ADPKD.

scientific article

Pre-eclampsia: Podocyturia predicts pre-eclampsia

scientific article published on 16 April 2013

Preoperative statin use is associated with a reduced risk of postoperative acute kidney injury ⬇️

scientific article published on November 13, 2012

Prevention: Intensive exercise associated with reduced risk of diabetic nephropathy in patients with type 1 diabetes mellitus

scientific article published on 17 February 2015

Prevention: Pediatric ECG screening

scientific article published on 22 May 2012

Prolonged cold ischaemic time reduces graft survival in kidneys from controlled-circulatory-death donors ⬇️

scientific article published on January 22, 2013

Protective role of NGAL in ANCA-induced glomerulonephritis

scientific article published on 26 June 2020

Regenerative medicine: Adipose stem cells fail to boost cartilage repair in rats

scientific article published on 18 September 2012

Regulation of nephrogenesis

scientific article published on 01 September 2018

Remote sensing and signalling in the kidney controls microbial metabolite levels

scientific article published on 01 October 2019

Renal IL-17 activity in candidiasis

scientific article published on 01 July 2018

Renal artery stenosis: renal artery stenosis-predicting responses to revascularization.

scientific article

Renal physiology: Aldosterone-dependent NCC activation.

scientific article

Renal physiology: HCO3- reclamation in the renal proximal tubule

scientific article published on 27 March 2017

Renin-Angiotensin system: Prorenin receptor: no role in the RAS?

scientific article published on 18 April 2016

Renin-angiotensin system: Targeting multiple RAS genes

scientific article published on 29 July 2014

Risk factors: Childhood kidney disease increases the risk of ESRD in adulthood

scientific article published on 12 February 2018

Risk factors: Contribution of low GFR to the global burden of disease.

scientific article

Risk factors: Relationship between sodium intake and mortality.

scientific article

Role of infection and molecular mimicry in the pathogenesis of anti-GBM disease

scientific article published on 05 June 2020

Safety of REG1 on the RADAR ⬇️

scientific article published on August 21, 2012

Severe reaction to radiotherapy for breast cancer as the presenting feature of ataxia telangiectasia ⬇️

scientific article published on December 6, 2011

Single-cell analysis identifies key pathways and prognostic markers in lupus nephritis

scientific article published on 01 August 2019

Single-cell analysis identifies key pathways and prognostic markers in lupus nephritis

scientific article published on 01 July 2019

Single-cell analysis of a biopsy sample

scientific article published on 01 October 2018

Some nephron progenitors fail to commit

scientific article published on 01 April 2019

Stones: A novel RNAi therapy for PH1.

scientific article published on 8 August 2016

Stones: A novel approach to stone prevention in cystinuria.

scientific article published on 27 February 2017

Stones: TNFRs mediate CaOx deposition in hyperoxaluria

scientific article published on 26 September 2016

Stones: Utilizing bacterial factors for kidney stone prevention

scientific article published on 31 October 2016

Study of ADTKD-MUC1 identifies a new lead for the treatment of toxic proteinopathies

scientific article published on 01 October 2019

Succinate homeostasis protects against lithogenesis and hypertension

scientific article published on 01 May 2019

The genetic architecture of blood pressure

scientific article published on 01 April 2019

The impact of chronic kidney disease on global health

scientific article published on 06 March 2020

Therapy: PHD inhibitors correct anaemia in CKD

scientific article published on 10 November 2015

Therapy: TNF inhibition suppresses angiogenic mechanisms implicated in RA

scientific article published on 31 May 2012

Thrombosis: New mechanism of thrombus formation in CKD

scientific article published on 17 October 2016

Thrombotic microangiopathy: Pregnancy outcomes in aHUS.

scientific article published on 15 January 2018

Tolerogenic cell therapy for glomerulonephritis

scientific article published on 01 November 2019

Transplantation. Erythropoietin inhibits proliferation of human T cells

scientific article published on 15 April 2014

Transplantation: A new tolerance strategy for diabetic recipients.

scientific article published on 18 July 2016

Transplantation: Continuous normothermic ex vivo perfusion improves kidney graft function

scientific article published on 16 August 2016

Transplantation: New tool for prediction of ESRD risk in living kidney donor candidates

scientific article published on 23 November 2015

Transplantation: Optimizing ECD graft outcomes

scientific article published on 18 August 2015

Transplantation: Pregnancy outcomes in living kidney donors.

scientific article published on 25 November 2014

Transplantation: Pro-tolerogenic properties of erythropoietin.

scientific article

Transplantation: Promising outcomes of HIV-positive-to-HIV-positive kidney transplantation

scientific article published on 24 February 2015

Transplantation: Reverse chimerism enables graft acceptance

scientific article published on 25 January 2016

Transplantation: Role of AECAS in graft rejection

scientific article published on 25 November 2014

Transplantation: Survival benefit of accepting a diabetic deceased donor kidney.

scientific article

Transplantation: The impact of donor CMV infection on kidney graft outcome.

scientific article published on 18 June 2013

Transplantation: The psychology of extraordinary altruism

scientific article published on 08 May 2017

Transplantation: increased recipient BMI is associated with adverse outcomes after kidney transplantation.

scientific article published on 8 October 2013

Transplantation: induction of chimerism and immune tolerance using belatacept

scientific article published on 02 December 2014

Tubular disease: Anti-LRP2 nephropathy

scientific article published on 13 November 2017

Tubular disease: mistargeted protein disrupts mitochondrial metabolism in inherited Fanconi syndrome

scientific article published on 21 January 2014

U-shaped associations between changes in blood pressure during dialysis and patient survival ⬇️

scientific article published on 09 July 2013

Uromodulin regulates oxidative stress

scientific article published on 01 January 2020

Use of CAR T cells as senolytic agents

scientific article published on 08 July 2020

Vasculitis: Abberrant glycosylation alters MPO antigenicity

scientific article published on 27 February 2017

Vasculitis: Potential role of an anti-moesin autoantibody in MPO-AAV.

scientific article published on 24 December 2013

Very mild presentation in adult with classical cellular phenotype of ataxia telangiectasia.

scientific article

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