List of works - Eder João Lenardão

3-(4-Chlorophenylselanyl)-1-methyl-1H-indole promotes recovery of neuropathic pain and depressive-like behavior induced by partial constriction of the sciatic nerve in mice

scientific article published on 24 April 2019

3-(4-Chlorophenylselanyl)-1-methyl-1H-indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice.

scientific article published on 10 March 2018

A Simple Zinc-Mediated Method for Selenium Addition to Michael Acceptors

scientific article published on 26 April 2020

A cell-based reporter assay for screening for EcR agonist/antagonist activity of natural ecdysteroids in Lepidoptera (Bm5) and Diptera (S2) cell cultures, followed by modeling of ecdysteroid-EcR interactions and normal mode analysis.

scientific article published on 26 September 2013

A selenium-based ionic liquid as a recyclable solvent for the catalyst-free synthesis of 3-selenylindoles.

scientific article published on 5 April 2013

Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice.

scientific article

Antinociceptive and anti-inflammatory effects of 1,2-bis-(4 methoxyphenylselanyl) styrene in mice: involvement of the serotonergic system

scientific article published on 27 March 2018

Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal.

scientific article

Antioxidant properties of (R)-Se-aryl thiazolidine-4-carboselenoate.

scientific article

Arylseleninic acid as a green, bench-stable selenylating agent: synthesis of selanylanilines and 3-selanylindoles

scientific article published on 30 June 2020

Atom Efficient Preparation of Zinc Selenates for the Synthesis of Selenol Esters under "On Water" Conditions.

scientific article published on 08 June 2017

Copper Catalysis and Organocatalysis Showing the Way: Synthesis of Selenium-containing Highly Functionalized 1,2,3-Triazoles.

scientific article published on 13 December 2017

Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system

scientific article published on 04 May 2019

Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice

scientific article published on 12 March 2019

Essential oil of the leaves of Eugenia uniflora L.: antioxidant and antimicrobial properties

scientific article published on 11 May 2012

Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice.

scientific article

Glycerol as Precursor of Organoselanyl and Organotellanyl Alkynes.

scientific article published on 2 March 2017

Green Hydroselenation of Aryl Alkynes: Divinyl Selenides as a Precursor of Resveratrol.

scientific article published on 20 February 2017

Green synthesis of (−)-isopulegol from (+)-citronellal: application to essential oil of citronella

Involvement of serotoninergic and adrenergic systems on the antidepressant-like effect of E. uniflora L. leaves essential oil and further analysis of its antioxidant activity.

scientific article published on 10 April 2013

Ionic liquid: an efficient and recyclable medium for synthesis of unsymmetrical diorganyl selenides promoted by InI

scientific article published on 08 September 2009

NMR chiral discrimination of chalcogen containing secondary alcohols

scientific article published on 15 November 2018

Organochalcogen compounds from glycerol: synthesis of new antioxidants

scientific article published on 27 August 2014

Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease

scientific article published on 13 May 2019

Recent Advances in the Synthesis of Selenophenes and Their Derivatives

scientific article published on 13 December 2020

Regioselective Synthesis of 1-Sulfanyl- and 1-Selanylindolizines

scientific article published on 14 May 2019

Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice

scientific article published on 14 June 2019

Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators

scientific article published on 19 July 2018

Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters.

scientific article published on 8 June 2015

Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

scientific article

Silver-Catalyzed Synthesis of Diaryl Selenides by Reaction of Diaryl Diselenides with Aryl Boronic Acids

scientific article published on 18 October 2016

Sonochemistry: An efficient alternative to the synthesis of 3-selanylindoles using CuI as catalyst.

scientific article published on 22 May 2015

Sweet Selenium: Synthesis and Properties of Selenium-Containing Sugars and Derivatives

scientific article published on 26 August 2020

Synthesis of (Z)-1-phenylseleno-1,4-diorganyl-1-buten-3-ynes: hydroselenation of symmetrical and unsymmetrical 1,4-diorganyl-1,3-butadiynes

Synthesis of Isoxazolines by the Electrophilic Chalcogenation of β,γ-Unsaturated Oximes: Fishing Novel Anti-Inflammatory Agents

scientific article published on 25 September 2019

Synthesis of Terminal Ethynyl Aryl Selenides and Sulfides Based on the Retro-Favorskii Reaction of Hydroxypropargyl Precursors.

scientific article published in August 2017

Synthesis of benzo[<i>b</i>]chalcogenophenes fused to selenophenes <i>via</i> intramolecular electrophilic cyclization of 1,3-diynes

scientific article published on 23 December 2020

Synthesis of chitosan derivatives with organoselenium and organosulfur compounds: Characterization, antimicrobial properties and application as biomaterials

scientific article published on 11 May 2019

Synthesis of vinyl selenides

scientific article published on 01 March 2009

The antioxidant and immunomodulatory compound 3-[(4-chlorophenyl)selanyl]-1-methyl-1H-indole attenuates depression-like behavior and cognitive impairment developed in a mouse model of breast tumor

scientific article published on 16 December 2019

The selenium-containing compound 3-((4-chlorophenyl)selanyl)-1-methyl-1H-indole reverses depressive-like behavior induced by acute restraint stress in mice: modulation of oxido-nitrosative stress and inflammatory pathway

scientific article published on 04 January 2019

Toxicological evaluation of 3-(4-Chlorophenylselanyl)-1-methyl-1H-indole through the bovine oocyte in vitro maturation model

scientific article published on 17 October 2019

Ultrasound-enhanced Ag-catalyzed decarboxylative coupling between α-keto acids and disulfides for the synthesis of thioesters

scientific article published on 17 July 2018

Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities

scientific article published on 13 June 2017

Ultrasound-promoted synthesis of 2-organoselanyl-naphthalenes using Oxone® in aqueous medium as an oxidizing agent.

scientific article published on 7 May 2018

Water and Aqueous Mixtures as Convenient Alternative Media for Organoselenium Chemistry

scientific article

α-Keto Acids: Acylating Agents in Organic Synthesis

scientific article published on 16 April 2019

List of works by Eder João Lenardão

3-(4-Chlorophenylselanyl)-1-methyl-1H-indole promotes recovery of neuropathic pain and depressive-like behavior induced by partial constriction of the sciatic nerve in mice

3-(4-Chlorophenylselanyl)-1-methyl-1H-indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice.

A Simple Zinc-Mediated Method for Selenium Addition to Michael Acceptors

A cell-based reporter assay for screening for EcR agonist/antagonist activity of natural ecdysteroids in Lepidoptera (Bm5) and Diptera (S2) cell cultures, followed by modeling of ecdysteroid-EcR interactions and normal mode analysis.

A selenium-based ionic liquid as a recyclable solvent for the catalyst-free synthesis of 3-selenylindoles.

Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice.

Antinociceptive and anti-inflammatory effects of 1,2-bis-(4 methoxyphenylselanyl) styrene in mice: involvement of the serotonergic system

Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal.

Antioxidant properties of (R)-Se-aryl thiazolidine-4-carboselenoate.

Arylseleninic acid as a green, bench-stable selenylating agent: synthesis of selanylanilines and 3-selanylindoles

Atom Efficient Preparation of Zinc Selenates for the Synthesis of Selenol Esters under "On Water" Conditions.

Copper Catalysis and Organocatalysis Showing the Way: Synthesis of Selenium-containing Highly Functionalized 1,2,3-Triazoles.

Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system

Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice

Essential oil of the leaves of Eugenia uniflora L.: antioxidant and antimicrobial properties

Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice.

Glycerol as Precursor of Organoselanyl and Organotellanyl Alkynes.

Green Hydroselenation of Aryl Alkynes: Divinyl Selenides as a Precursor of Resveratrol.

Green synthesis of (−)-isopulegol from (+)-citronellal: application to essential oil of citronella

Involvement of serotoninergic and adrenergic systems on the antidepressant-like effect of E. uniflora L. leaves essential oil and further analysis of its antioxidant activity.

Ionic liquid: an efficient and recyclable medium for synthesis of unsymmetrical diorganyl selenides promoted by InI

NMR chiral discrimination of chalcogen containing secondary alcohols

Organochalcogen compounds from glycerol: synthesis of new antioxidants

Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease

Recent Advances in the Synthesis of Selenophenes and Their Derivatives

Regioselective Synthesis of 1-Sulfanyl- and 1-Selanylindolizines

Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice

Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators

Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters.

Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

Silver-Catalyzed Synthesis of Diaryl Selenides by Reaction of Diaryl Diselenides with Aryl Boronic Acids

Sonochemistry: An efficient alternative to the synthesis of 3-selanylindoles using CuI as catalyst.

Sweet Selenium: Synthesis and Properties of Selenium-Containing Sugars and Derivatives

Synthesis of (Z)-1-phenylseleno-1,4-diorganyl-1-buten-3-ynes: hydroselenation of symmetrical and unsymmetrical 1,4-diorganyl-1,3-butadiynes

Synthesis of Isoxazolines by the Electrophilic Chalcogenation of β,γ-Unsaturated Oximes: Fishing Novel Anti-Inflammatory Agents

Synthesis of Terminal Ethynyl Aryl Selenides and Sulfides Based on the Retro-Favorskii Reaction of Hydroxypropargyl Precursors.

Synthesis of benzo[<i>b</i>]chalcogenophenes fused to selenophenes <i>via</i> intramolecular electrophilic cyclization of 1,3-diynes

Synthesis of chitosan derivatives with organoselenium and organosulfur compounds: Characterization, antimicrobial properties and application as biomaterials

Synthesis of vinyl selenides

The antioxidant and immunomodulatory compound 3-[(4-chlorophenyl)selanyl]-1-methyl-1H-indole attenuates depression-like behavior and cognitive impairment developed in a mouse model of breast tumor

The selenium-containing compound 3-((4-chlorophenyl)selanyl)-1-methyl-1H-indole reverses depressive-like behavior induced by acute restraint stress in mice: modulation of oxido-nitrosative stress and inflammatory pathway

Toxicological evaluation of 3-(4-Chlorophenylselanyl)-1-methyl-1H-indole through the bovine oocyte in vitro maturation model

Ultrasound-enhanced Ag-catalyzed decarboxylative coupling between α-keto acids and disulfides for the synthesis of thioesters

Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities

Ultrasound-promoted synthesis of 2-organoselanyl-naphthalenes using Oxone® in aqueous medium as an oxidizing agent.

Water and Aqueous Mixtures as Convenient Alternative Media for Organoselenium Chemistry

α-Keto Acids: Acylating Agents in Organic Synthesis