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List of works by Andrew P Hinck

A Novel TGF-β Trap Blocks Chemotherapeutics-Induced TGF-β1 Signaling and Enhances Their Anticancer Activity in Gynecological Cancers.

scientific article published on 16 March 2018

ALK1 signaling in development and disease: new paradigms.

scientific article published on 4 September 2017

An introduction to the special issue on biomolecular NMR.

scientific article

Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor.

scientific article published on December 2009

Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers

scientific article published on 5 September 2014

Characterization of Hydride Transfer to Flavin Adenine Dinucleotide in Neuronal Nitric Oxide Synthase Reductase Domain: Geometric Relationship between the Nicotinamide and Isoalloxazine Rings ⬇️

scientific article published on November 1, 2001

Class II cytokine common receptors: something old, something new

scientific article published on 01 May 2010

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2

scientific article published on 16 July 2015

Direct evidence for a phenylalanine site in the regulatory domain of phenylalanine hydroxylase ⬇️

scientific article published on October 14, 2010

Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells.

scientific article published on 29 September 2014

Evaluation of competing J domain:Hsp70 complex models in light of existing mutational and NMR data.

scientific article published on 7 March 2012

Kinetic, dynamic, ligand binding properties, and structural models of a dual-substrate specific nudix hydrolase from Schizosaccharomyces pombe.

scientific article

Nuclear Magnetic Resonance Structural Mapping Reveals Promiscuous Interactions between Clathrin-Box Motif Sequences and the N-Terminal Domain of the Clathrin Heavy Chain

scientific article published on 16 April 2015

Peptide ligands that use a novel binding site to target both TGF-β receptors.

scientific article

Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily

scientific article published on January 2016

Solvent Effects on the Energetics of Prolyl Peptide Bond Isomerization

scientific article

Structural Biology and Evolution of the TGF-β Family

scientific article published on 16 September 2016

Structural basis for potency differences between GDF8 and GDF11.

scientific article

Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family

scientific article published on 10 October 2019

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity

scientific article published on 17 July 2019

Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily.

scientific article published on 28 May 2012

Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties.

scientific article published on 2 August 2012

Structure-guided engineering of TGF-βs for the development of novel inhibitors and probing mechanism

scientific article published on 07 July 2018

Structures of TGF-β Receptor Complexes: Implications for Function and Therapeutic Intervention Using Ligand Traps ⬇️

scientific article published on December 1, 2011

TGF-β Antagonists: Same Knot, but Different Hold ⬇️

scientific article published on August 6, 2013

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

scientific article

TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition

scientific article

TGF-β2 uses the concave surface of its extended finger region to bind betaglycan's ZP domain via three residues specific to TGF-β and inhibin-α

scientific article published on 31 December 2018

The Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers

scientific article

The Solution Structure of the Regulatory Domain of Tyrosine Hydroxylase

scientific article

The growth-suppressive function of the polycomb group protein polyhomeotic is mediated by polymerization of its sterile alpha motif (SAM) domain

scientific article published on 24 January 2012

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