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List of works by Nicolas Hohmann

A follow-up report on potential drug interactions with clementines: Two single case experiments show no effect on CYP3A-dependent midazolam clearance

scientific article published on 21 March 2019

A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions.

scientific article published on 8 February 2013

Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial.

scientific article published on 16 March 2015

Autoinhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics.

scientific article published on 29 March 2017

CYP3A activity: towards dose adaptation to the individual.

scientific article published on 7 March 2016

Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole.

scientific article published on 28 May 2016

Effects and risks associated with novel psychoactive substances: mislabeling and sale as bath salts, spice, and research chemicals

scientific article published on February 2014

First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B.

scientific article

Impact of patient education on plasma concentrations and effectiveness of posaconazole oral suspension under clinical conditions

scientific article published on 02 August 2018

Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans

scientific article

No Increased Risk of Ketoconazole Toxicity in Drug-Drug Interaction Studies.

scientific article

Normal CYP3A activity during arsenic trioxide therapy

scientific article published on 16 April 2014

Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry.

scientific article published on 15 January 2012

Response to "can CYP3A activity be evaluated for drug interaction using a nanogram dose of probe drug?": evaluation of CYP3A activity with microdoses of midazolam.

scientific article published on 6 February 2014

Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses

scientific article published on 09 August 2019

St. John's wort treatment in women bears risks beyond pharmacokinetic drug interactions

scientific article

Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity

scientific article

The first-in-human study of the pan-PIM kinase inhibitor PIM447 in patients with relapsed and/or refractory multiple myeloma

scientific article published on 15 May 2019

Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans.

scientific article published on May 2016

Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry after chlorzoxazone microdosing.

scientific article published on 31 May 2016

Use of microdose phenotyping to individualise dosing of patients

scientific article published on 30 April 2015

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