List of works by Maria Francesca Santolla

(6-bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (carbhydraz) acts as a GPER agonist in breast cancer cells.

scientific article

A Bodipy as a luminescent probe for detection of the G protein estrogen receptor (GPER)

scientific article published on 24 September 2015

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models

scientific article

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

scientific article published in Nature Communications

Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.

scientific article

Copper activates HIF-1α/GPER/VEGF signalling in cancer cells

scientific article

Corrigendum to "Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme"

scientific article published on 09 September 2020

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)

scientific article

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells

scientific article published on 06 February 2019

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression

scientific article published on 07 March 2019

GPER mediates activation of HIF1α/VEGF signaling by estrogens

scientific article

GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.

scientific article published on 24 June 2016

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

scientific article published on January 2013

Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts

scientific article

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

scientific article

Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands.

scientific article

Niacin activates the G protein estrogen receptor (GPER)-mediated signalling.

scientific article

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.

scientific article

Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme

scientific article published on 22 July 2019

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.

scientific article published on 30 July 2015

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells.

scientific article published on 30 June 2016

The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives

scientific article published on 18 October 2020

miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.

scientific article published on 2 May 2018

miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs)

scientific article published on 09 November 2018