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List of works by Thomas Botton

Activating MET kinase rearrangements in melanoma and Spitz tumours

scientific article published on 27 May 2015

Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation

scientific article published on 01 July 2018

CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing.

scientific article

Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion

scientific article

Comment on 'Testing for BRAF fusions in patients with advanced BRAF/NRAS/KIT wild-type melanomas permits to identify patients who could benefit of anti-MEK targeted therapy'

scientific article published on 18 December 2019

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

scientific article

Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses

scientific article published on 01 October 2019

Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion.

scientific article published on 5 April 2018

In vitro and in vivo anti-melanoma effects of ciglitazone.

scientific article

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

scientific article

Melanoma BRAF fusions--letter

scientific article published in December 2014

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

scientific article

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.

scientific article published on 31 January 2011

NTRK3 kinase fusions in Spitz tumours

scientific article published on August 2016

Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy

scientific article

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