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List of works by Christopher D Scharer

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells

scientific article published on June 2016

Antibody-secreting cell destiny emerges during the initial stages of B-cell activation

scientific article published on 10 August 2020

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.

scientific article

B cell differentiation is associated with reprogramming the CCCTC binding factor-dependent chromatin architecture of the murine MHC class II locus

scientific article

Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence

scientific article

Chemically defined serum-free and xeno-free media for multiple cell lineages

scientific article published on October 2014

Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types

scientific article

Cutting Edge: Chromatin Accessibility Programs CD8 T Cell Memory.

scientific article

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

article

EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production

scientific article published on 29 December 2017

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells

scientific article published on 17 January 2020

Epigenetic programming underpins B cell dysfunction in human SLE

scientific article published on 01 July 2019

Ethanol Alters Proliferation and Differentiation of Normal and Chromosomally Abnormal Human Embryonic Stem Cell‐Derived Neurospheres ⬇️

scientific article published on May 21, 2013

GABRB3 gene expression increases upon ethanol exposure in human embryonic stem cells.

scientific article published on June 2011

Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells

scientific article

Global DNA methylation remodeling accompanies CD8 T cell effector function.

scientific article published on 16 August 2013

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons

scientific article published on 04 November 2020

IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation.

scientific article published on 15 May 2019

IgM, IgG, and IgA Influenza-Specific Plasma Cells Express Divergent Transcriptomes

scientific article published on 09 September 2019

LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development

scientific article published on 06 September 2019

Lactobacilli Modulate Epithelial Cytoprotection through the Nrf2 Pathway.

scientific article

Lectins Identify Glycan Biomarkers on Glioblastoma-Derived Cancer Stem Cells ⬇️

scientific article published on April 27, 2012

Low ethanol concentration alters CHRNA5 RNA levels during early human development

scientific article

Murine gammaherpesvirus infection is skewed toward Igλ+ B cells expressing a specific heavy chain V-segment

scientific article published on 30 April 2020

NF-κB regulates PD-1 expression in macrophages

scientific article

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.

scientific article published on 27 April 2018

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

scientific article published on 08 August 2016

Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen

scientific article published on 01 June 2018

Roadmap to a plasma cell: Epigenetic and transcriptional cues that guide B cell differentiation

scientific article published on 05 December 2020

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

scientific article published on 23 October 2020

Somatic Diversification of Rearranged Antibody Gene Segments by Intra- and Interchromosomal Templated Mutagenesis

scientific article published on 13 April 2022

T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells

scientific article published on 07 May 2019

The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation

scientific article published on 19 September 2018

ZBTB32 Is an Early Repressor of the CIITA and MHC Class II Gene Expression during B Cell Differentiation to Plasma Cells ⬇️

scientific article published on July 30, 2012

ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.

scientific article published on 29 June 2016

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