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List of works by Frank Kramer

A gene expression signature for chemoradiosensitivity of colorectal cancer cells.

scientific article published on November 2010

A simulation framework for correlated count data of features subsets in high-throughput sequencing or proteomics experiments.

scientific article

Building pathway graphs from BioPAX data in R.

scientific article

Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy.

scientific article

Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling.

scientific article published on 15 August 2017

Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene

scientific article published on 22 August 2012

Comparative study on gene set and pathway topology-based enrichment methods.

scientific article published on 22 October 2015

Data-dependent visualization of biological networks in the web-browser with NDExEdit

scientific article published on 08 June 2022

DrNote: An open medical annotation service

scientific article published on 15 August 2022

Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B.

scientific article

Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.

scientific article published on 7 August 2013

Multipath: An R Package to Generate Integrated Reproducible Pathway Models

scientific article published on 21 December 2020

New perspectives: systems medicine in cardiovascular disease.

scientific article published on 25 April 2018

Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data

scientific article

Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas ⬇️

scientific article published on December 8, 2012

Preoperative Prediction of Lymph Node Status by Circulating Mir-18b and Mir-20a During Chemoradiotherapy in Patients with Rectal Cancer.

scientific article published in September 2015

Prognostic Value of MicroRNAs in Preoperative Treated Rectal Cancer

scientific article published on 15 April 2016

R-based software for the integration of pathway data into bioinformatic algorithms

scientific article

Reconstruction of Protein Networks Using Reverse-Phase Protein Array Data

scientific article

STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo.

scientific article

Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.

scientific article published on 8 October 2011

Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.

scientific article published on 4 January 2012

The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness

scientific article published on 07 January 2019

UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib

scientific article

Working with Ontologies.

scientific article published on January 2017

mully: An R Package to Create, Modify and Visualize Multilayered Graphs

article

ndexr - an R package to interface with the Network Data Exchange.

scientific article published on 26 October 2017

rBiopaxParser--an R package to parse, modify and visualize BioPAX data.

scientific article

β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis ⬇️

scientific article published on December 20, 2010

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