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List of works by Chen Ling

A simple method to increase the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo.

scientific article

AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo

scientific article published on 09 March 2020

Cellulose-based injectable hydrogel composite for pH-responsive and controllable drug delivery

scientific article published on 17 August 2019

Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses

scientific article published on 18 July 2016

Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells

scientific article published on 13 August 2015

Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.

scientific article

Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo.

scientific article

High-Efficiency Transduction of Primary Human Hematopoietic Stem Cells and Erythroid Lineage-Restricted Expression by Optimized AAV6 Serotype Vectors In Vitro and in a Murine Xenograft Model In Vivo ⬇️

scientific article published on March 14, 2013

High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing.

scientific article published on 19 October 2016

High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

scientific article

High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy

scientific article

High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.

scientific article

High-efficiency transduction of liver cancer cells by recombinant adeno-associated virus serotype 3 vectors.

scientific article

Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3

scientific article

Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates

scientific article published on 01 June 2018

Lignin nanotubes as vehicles for gene delivery into human cells.

scientific article published on 17 December 2013

Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitation

scientific article

Negative autoregulation of Epstein-Barr virus (EBV) replicative gene expression by EBV SM protein.

scientific article published on 10 June 2009

Neuritin Enhances Synaptic Transmission in Medial Prefrontal Cortex in Mice by Increasing CaV3.3 Surface Expression.

scientific article published on 4 May 2017

Neuritin reverses deficits in murine novel object associative recognition memory caused by exposure to extremely low-frequency (50 Hz) electromagnetic fields.

scientific article

Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?

scientific article

Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo.

scientific article published on August 2013

Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy.

scientific article published on 12 November 2013

Reprogramming Immune Response With Capsid-Optimized AAV6 Vectors for Immunotherapy of Cancer

scientific article

Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model

scientific article

Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo

scientific article

Strategies to generate high-titer, high-potency recombinant AAV3 serotype vectors

scientific article published on 4 May 2016

TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer

scientific article published on 01 June 2019

The Adeno-Associated Virus Genome Packaging Puzzle

scientific article

The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload-mediated hepatic inflammation.

scientific article published on 27 June 2017

mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system

scientific article published on 30 March 2016

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