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List of works by Fumika Karaki

7-azabicyclo[2.2.1]heptane as a structural motif to block mutagenicity of nitrosamines

scientific article published on 02 March 2011

A New Lead Identification Strategy: Screening an sp3 -rich and Lead-like Compound Library Composed of 7-Azanorbornane Derivatives

scientific article published on 20 September 2019

A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach

scientific article published on 01 March 2019

C-Homomorphinan Derivatives as Lead Compounds to Obtain Safer and More Clinically Useful Analgesics.

scientific article

Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site

scientific article published on 01 March 2013

Generation of cycloheptynes and cyclooctynes via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates

scientific article published on 01 May 2015

Image-based screen capturing misfolding status of Niemann-Pick type C1 identifies potential candidates for chaperone drugs

scientific article published on 14 December 2020

Phenanthridin-6-one derivatives as the first class of non-steroidal pharmacological chaperones for Niemann-Pick disease type C1 protein.

scientific article published on 22 April 2017

Reactivity of 7-Azanorbornenes in Bioorthogonal Inverse Electron-Demand Diels-Alder Reactions

scientific article published in 2017

Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.

scientific article published on 17 June 2013

Structure-activity relationship study of non-steroidal NPC1L1 ligands identified through cell-based assay using pharmacological chaperone effect as a readout.

scientific article

Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein

scientific article published on 02 June 2014

Synthesis of multisubstituted cycloalkenes through carbomagnesiation of strained cycloalkynes

scientific article published on 28 May 2020

Vildagliptin and its metabolite M20.7 induce the expression of S100A8 and S100A9 in human hepatoma HepG2 and leukemia HL-60 cells.

scientific article published on 19 October 2016

Visible-light-triggered release of nitric oxide from N-pyramidal nitrosamines.

scientific article published on 16 December 2011

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