List of works - Mikio Shoji

A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer's Disease by Peptidome Technology

scientific article published on 01 January 2020

A Product of the Human Gene Adjacent to parkin Is a Component of Lewy Bodies and Suppresses Pael Receptor-induced Cell Death ⬇️

scientific article published on October 7, 2003

A case of hereditary neuropathy with liability to pressure palsies due to push-up exercise.

scientific article published on 24 June 2017

A case of paroxysmal kinesigenic dyskinesia with spastic paraparesis

scientific article published in October 2002

A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P + A53T transgenic mice.

scientific article

A novel mutation in the arylsulfatase A gene associated with adult-onset metachromatic leukodystrophy without clinical evidence of neuropathy

scientific article published on 3 October 2008

A reproducible assay of polymerase chain reaction to detect trinucleotide repeat expansion of Huntington's disease and senile chorea

scientific article published in February 1996

A small trinucleotide expansion in the TBP gene gives rise to a sporadic case of SCA17 with abnormal putaminal findings on MRI

scientific article published on 15 December 2008

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease

scientific article published on 11 March 2020

Accumulation of Amyloid β Protein in Transgenic Mice ⬇️

scientific article published on January 1, 1998

Accumulation of apolipoprotein E and beta-amyloid-like protein in a trace of the hippocampal CA1 pyramidal cell layer after ischaemic delayed neuronal death.

scientific article published in November 1996

Accumulation of beta-amyloid fibrils in pancreas of transgenic mice

scientific article published in March 1996

Aging and are determinative factors of plasma A42 levels

scientific article published on 07 September 2018

Alpha 1-antichymotrypsin is present in diffuse senile plaques. A comparative study of beta-protein and alpha 1-antichymotrypsin immunostaining in the Alzheimer brain ⬇️

scientific article published on January 1, 1991

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.

scientific article

Alzheimer amyloid beta-protein precursor in sperm development ⬇️

scientific article published on November 1, 1990

Amyloid beta protein precursor accumulates in swollen neurites throughout rat brain with aging

scientific article

Amyloid beta-protein ending at Thr43 is a minor component of some diffuse plaques in the Alzheimer's disease brain, but is not found in cerebrovascular amyloid

scientific article published on 01 December 1995

Amyloid β accelerates phosphorylation of tau and neurofibrillary tangle formation in an amyloid precursor protein and tau double-transgenic mouse model

article

An autopsy case of primary lateral sclerosis with Alzheimer's disease

scientific article published on 20 March 2020

An unusual case of elderly-onset cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) with multiple cerebrovascular risk factors.

scientific article published on 19 September 2010

Analysis of spinocerebellar ataxia type 2 in Gunma Prefecture in Japan: CAG trinucleotide expansion and clinical characteristics ⬇️

scientific article published on April 1, 1998

Analysis of the McLeod syndrome gene in three patients with neuroacanthocytosis ⬇️

scientific article published on September 10, 1997

Apolipoprotein E Accumulates with the Progression of A0 Deposition in Transgenic Mice ⬇️

scientific article published on November 1, 1997

Biomarkers for Alzheimer's disease: after Alzheimer's disease neuroimaging initiative studies

scientific article

Biomarkers of the dementia.

scientific article

Cerebrospinal Fluid and Plasma Biomarkers in Neurodegenerative Diseases

scientific article published on 01 January 2019

Cerebrospinal Fluid and Plasma Tau as a Biomarker for Brain Tauopathy

scientific article published on 01 January 2019

Cerebrospinal fluid Aβ40 and Aβ42: Natural course and clinical usefulness.

scientific article

CogEvo, a cognitive function balancer, is a sensitive and easy psychiatric test battery for age-related cognitive decline

scientific article published on 18 December 2019

Cognitive and affective impairments of a novel SCA/MND crossroad mutation Asidan ⬇️

scientific article published on February 21, 2012

Colocalization of Bunina bodies and TDP-43 inclusions in a case of sporadic amyotrophic lateral sclerosis with Lewy body-like hyaline inclusions

scientific article published on 25 June 2018

Combination assay of CSF Tau, Aβ1-40 and Aβ1-42(43) as a biochemical marker of Alzheimer's disease ⬇️

scientific article published on June 30, 1998

Conversion and reversion

scientific article published on 01 December 2011

Development of therapies of Alzheimer's disease ⬇️

scientific article published on September 1, 2003

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

scientific article

Disappearance of MRI imaging signals in a patient with neuronal intranuclear inclusion disease

scientific article published on 23 February 2018

Disease modifying therapies for Alzheimer's disease targeting Aβ oligomers: implications for therapeutic mechanisms

scientific article (publication date: 2013)

Dissociation of β-amyloid from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates β-amyloid-42 assembly ⬇️

scientific article published on March 10, 2011

Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia

scientific article published on 01 January 2003

Distribution of inducible nitric oxide synthase and cell proliferation in rat brain after transient middle cerebral artery occlusion.

scientific article published on 15 May 2006

Drug therapy for Alzheimer's disease

scientific article published on July 2010

Enhanced expression of phospho-Akt by electro-acupuncture in normal rat brain

scientific article published in October 2002

Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

scientific article (publication date: 6 March 2011)

Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy ⬇️

scientific article published on January 13, 2011

Functional improvement by electro-acupuncture after transient middle cerebral artery occlusion in rats

scientific article published in July 2003

Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese.

scientific article

Glial cell line-derived neurotrophic factor protein prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis

scientific article published on March 2003

Glutamate enhances caspase-3 immunoreactivity in cultured spinal cord neurons of newborn rats

scientific article published in April 2003

Highly polysialylated neural cell adhesion molecule (PSA-NCAM) positive cells are increased and change localization in rat hippocampus by exposure to repeated kindled seizures

scientific article published on 01 January 2003

Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene ⬇️

scientific article published on November 7, 2003

Immunoelectron microscopic localization of amyloid beta protein in the diffuse plaques of Alzheimer-type dementia

scientific article

Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population.

scientific article published in January 2014

Longitudinal study of cerebrospinal fluid levels of tau, Aβ1–40, and Aβ1–42(43) in Alzheimer's disease: A study in Japan ⬇️

scientific article published on July 1, 1998

Lysosomal generation of amyloid β protein species in transgenic mice ⬇️

scientific article published on August 15, 1997

MicroRNA expression profiles of neuron-derived extracellular vesicles in plasma from patients with amyotrophic lateral sclerosis

scientific article published on 04 June 2019

Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: clinical molecular and genetic studies on Alzheimer's disease

scientific article

Molecular mechanisms of ischemic neuronal cell death--with relevance to Alzheimer's disease

scientific article published on September 2006

Mutation analysis of the CACNL1A3 gene in Japanese hypokalemic periodic paralysis families

scientific article published on 01 December 1997

Nationwide survey on cerebral amyloid angiopathy in Japan

scientific article published on 18 July 2019

Neuropathology of PARK14 is identical to idiopathic Parkinson's disease

scientific article published on 17 February 2017

Novel ELISAs to measure total and phosphorylated tau in cerebrospinal fluid

scientific article published on 08 February 2020

Novel GBE1 mutation in a Japanese family with adult polyglucosan body disease.

scientific article published on 24 February 2017

Oral Immunization with Soybean Storage Protein Containing Amyloid-β 4-10 Prevents Spatial Learning Decline

scientific article published on 01 January 2019

Passive immunization of the Abeta42(43) C-terminal-specific antibody BC05 in a mouse model of Alzheimer's disease

scientific article published in January 2005

Perineuritis Successfully Treated with Early Aggressive Immunotherapy

scientific article published on 27 June 2019

Prevalence of Autosomal Dominant Cerebellar Ataxia in Aomori, the Northernmost Prefecture of Honshu, Japan ⬇️

scientific article published on November 15, 2010

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

scientific article published on October 2, 1992

Protection against ischemic brain damage by GDNF affecting cell survival and death signals

scientific article published on April 2003

Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST3.

scientific article published on 16 September 2010

Quantitative Measurement of Cerebrospinal Fluid Amyloid-β Species by Mass Spectrometry

scientific article published on 15 December 2020

Randomized double-blind placebo-controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease

scientific article

Severe Chronic Inflammatory Demyelinating Polyneuropathy Ameliorated following High-dose (3 g/kg) Intravenous Immunoglobulin Therapy.

scientific article published on 19 November 2018

Severity dependent up-regulations of LOX-1 and MCP-1 in early sclerotic changes of common carotid arteries in spontaneously hypertensive rats

scientific article published in October 2004

Spinocerebellar ataxia type 8: molecular genetic comparisons and haplotype analysis of 37 families with ataxia

scientific article

Superoxide dismutase-encoding gene of the obligate anaerobe Porphyromonas gingivalis is regulated by the redox-sensing transcription activator OxyR

scientific article published on 01 April 2006

Sustained induction of survival p-AKT and p-ERK signals after transient hypoxia in mice spinal cord with G93A mutant human SOD1 protein ⬇️

scientific article published on November 15, 2003

Systemic overexpression of a C-terminal fragment of human amyloid beta-protein precursor causes accumulation of Alzheimer beta-amyloid fibrils in pancreas of transgenic mice.

scientific article published in January 1996

Tardive decrease of astrocytic glutamate transporter protein in transgenic mice with ALS-linked mutant SOD1.

scientific article published in September 2002

Targeting of post-ischemic cerebral endothelium in rat by liposomes bearing polyethylene glycol-coupled transferrin

scientific article published in April 2003

Temporal and spacial changes of BrdU immunoreactivity in amygdala kindling development

scientific article published in September 2002

Temporal and spacial changes of highly polysialylated neural cell adhesion molecule immunoreactivity in amygdala kindling development

scientific article published in January 2003

Temporal profile of neural stem cell proliferation in the subventricular zone after ischemia/hypoxia in the neonatal rat brain.

scientific article published in June 2006

Three steps of neural stem cells development in gerbil dentate gyrus after transient ischemia

scientific article published in April 2002

Trend and outlook in clinical research for dementia

scientific article published on 01 October 2011

Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes

scientific article published on January 1, 1992

[Biomarker of dementia: clinical and preclinical diagnosis].

scientific article published in May 2012

[DIAN/DIAN-J/DIAN-TU]

scientific article published on 01 July 2017

[Expert/neurologist∼clinical]

scientific article published on 01 November 2011

[Functional Assessment Staging (FAST)]

scientific article published on 01 October 2011

[Programs for continuing medical education: a session; 3. Dementia: diagnosis and therapy].

scientific article

List of works by Mikio Shoji

A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer's Disease by Peptidome Technology

A Product of the Human Gene Adjacent to parkin Is a Component of Lewy Bodies and Suppresses Pael Receptor-induced Cell Death ⬇️

A case of hereditary neuropathy with liability to pressure palsies due to push-up exercise.

A case of paroxysmal kinesigenic dyskinesia with spastic paraparesis

A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P + A53T transgenic mice.

A novel mutation in the arylsulfatase A gene associated with adult-onset metachromatic leukodystrophy without clinical evidence of neuropathy

A reproducible assay of polymerase chain reaction to detect trinucleotide repeat expansion of Huntington's disease and senile chorea

A small trinucleotide expansion in the TBP gene gives rise to a sporadic case of SCA17 with abnormal putaminal findings on MRI

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease

Accumulation of Amyloid β Protein in Transgenic Mice ⬇️

Accumulation of apolipoprotein E and beta-amyloid-like protein in a trace of the hippocampal CA1 pyramidal cell layer after ischaemic delayed neuronal death.

Accumulation of beta-amyloid fibrils in pancreas of transgenic mice

Aging and are determinative factors of plasma A42 levels

Alpha 1-antichymotrypsin is present in diffuse senile plaques. A comparative study of beta-protein and alpha 1-antichymotrypsin immunostaining in the Alzheimer brain ⬇️

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.

Alzheimer amyloid beta-protein precursor in sperm development ⬇️

Amyloid beta protein precursor accumulates in swollen neurites throughout rat brain with aging

Amyloid beta-protein ending at Thr43 is a minor component of some diffuse plaques in the Alzheimer's disease brain, but is not found in cerebrovascular amyloid

Amyloid β accelerates phosphorylation of tau and neurofibrillary tangle formation in an amyloid precursor protein and tau double-transgenic mouse model

An autopsy case of primary lateral sclerosis with Alzheimer's disease

An unusual case of elderly-onset cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) with multiple cerebrovascular risk factors.

Analysis of spinocerebellar ataxia type 2 in Gunma Prefecture in Japan: CAG trinucleotide expansion and clinical characteristics ⬇️

Analysis of the McLeod syndrome gene in three patients with neuroacanthocytosis ⬇️

Apolipoprotein E Accumulates with the Progression of A0 Deposition in Transgenic Mice ⬇️

Biomarkers for Alzheimer's disease: after Alzheimer's disease neuroimaging initiative studies

Biomarkers of the dementia.

Cerebrospinal Fluid and Plasma Biomarkers in Neurodegenerative Diseases

Cerebrospinal Fluid and Plasma Tau as a Biomarker for Brain Tauopathy

Cerebrospinal fluid Aβ40 and Aβ42: Natural course and clinical usefulness.

CogEvo, a cognitive function balancer, is a sensitive and easy psychiatric test battery for age-related cognitive decline

Cognitive and affective impairments of a novel SCA/MND crossroad mutation Asidan ⬇️

Colocalization of Bunina bodies and TDP-43 inclusions in a case of sporadic amyotrophic lateral sclerosis with Lewy body-like hyaline inclusions

Combination assay of CSF Tau, Aβ1-40 and Aβ1-42(43) as a biochemical marker of Alzheimer's disease ⬇️

Conversion and reversion

Development of therapies of Alzheimer's disease ⬇️

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

Disappearance of MRI imaging signals in a patient with neuronal intranuclear inclusion disease

Disease modifying therapies for Alzheimer's disease targeting Aβ oligomers: implications for therapeutic mechanisms

Dissociation of β-amyloid from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates β-amyloid-42 assembly ⬇️

Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia

Distribution of inducible nitric oxide synthase and cell proliferation in rat brain after transient middle cerebral artery occlusion.

Drug therapy for Alzheimer's disease

Enhanced expression of phospho-Akt by electro-acupuncture in normal rat brain

Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy ⬇️

Functional improvement by electro-acupuncture after transient middle cerebral artery occlusion in rats

Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese.

Glial cell line-derived neurotrophic factor protein prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis

Glutamate enhances caspase-3 immunoreactivity in cultured spinal cord neurons of newborn rats

Highly polysialylated neural cell adhesion molecule (PSA-NCAM) positive cells are increased and change localization in rat hippocampus by exposure to repeated kindled seizures

Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene ⬇️

Immunoelectron microscopic localization of amyloid beta protein in the diffuse plaques of Alzheimer-type dementia

Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population.

Longitudinal study of cerebrospinal fluid levels of tau, Aβ1–40, and Aβ1–42(43) in Alzheimer's disease: A study in Japan ⬇️

Lysosomal generation of amyloid β protein species in transgenic mice ⬇️

MicroRNA expression profiles of neuron-derived extracellular vesicles in plasma from patients with amyotrophic lateral sclerosis

Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: clinical molecular and genetic studies on Alzheimer's disease

Molecular mechanisms of ischemic neuronal cell death--with relevance to Alzheimer's disease

Mutation analysis of the CACNL1A3 gene in Japanese hypokalemic periodic paralysis families

Nationwide survey on cerebral amyloid angiopathy in Japan

Neuropathology of PARK14 is identical to idiopathic Parkinson's disease

Novel ELISAs to measure total and phosphorylated tau in cerebrospinal fluid

Novel GBE1 mutation in a Japanese family with adult polyglucosan body disease.

Oral Immunization with Soybean Storage Protein Containing Amyloid-β 4-10 Prevents Spatial Learning Decline

Passive immunization of the Abeta42(43) C-terminal-specific antibody BC05 in a mouse model of Alzheimer's disease

Perineuritis Successfully Treated with Early Aggressive Immunotherapy

Prevalence of Autosomal Dominant Cerebellar Ataxia in Aomori, the Northernmost Prefecture of Honshu, Japan ⬇️

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

Protection against ischemic brain damage by GDNF affecting cell survival and death signals

Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST3.

Quantitative Measurement of Cerebrospinal Fluid Amyloid-β Species by Mass Spectrometry

Randomized double-blind placebo-controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease

Severe Chronic Inflammatory Demyelinating Polyneuropathy Ameliorated following High-dose (3 g/kg) Intravenous Immunoglobulin Therapy.

Severity dependent up-regulations of LOX-1 and MCP-1 in early sclerotic changes of common carotid arteries in spontaneously hypertensive rats

Spinocerebellar ataxia type 8: molecular genetic comparisons and haplotype analysis of 37 families with ataxia

Superoxide dismutase-encoding gene of the obligate anaerobe Porphyromonas gingivalis is regulated by the redox-sensing transcription activator OxyR

Sustained induction of survival p-AKT and p-ERK signals after transient hypoxia in mice spinal cord with G93A mutant human SOD1 protein ⬇️

Systemic overexpression of a C-terminal fragment of human amyloid beta-protein precursor causes accumulation of Alzheimer beta-amyloid fibrils in pancreas of transgenic mice.

Tardive decrease of astrocytic glutamate transporter protein in transgenic mice with ALS-linked mutant SOD1.