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List of works by Debora Soncini

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells

scientific article published on 11 May 2015

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells ⬇️

scientific article published on July 23, 2013

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.

scientific article published on 12 October 2017

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.

scientific article published on 10 June 2016

Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.

scientific article published on November 2010

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition

scientific article

Exploiting tumor vulnerabilities: NAD(+)-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies

scientific article published on 19 July 2016

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

scientific article published in May 2015

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression

scientific article

Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma

scientific article published on 19 August 2019

Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience.

scientific article published on June 2013

Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity

scientific article

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

scientific article published on 19 September 2017

Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors

scientific article published on 28 April 2016

Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.

scientific article published on May 2012

The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses ⬇️

scientific article published on October 18, 2012

Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques

scientific article published on 06 February 2014

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