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List of works by Christine M. Lovly

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Identifying a Clinically Applicable Mutational Burden Threshold as a Potential Biomarker of Response to Immune Checkpoint Therapy in Solid Tumors

scientific article published on 07 December 2017
BRAF internal deletions and resistance to BRAF/MEK inhibitor therapy.

scientific article published on 24 November 2017
ALK Fusion Partners Impact Response to ALK Inhibition: Differential Effects on Sensitivity, Cellular Phenotypes, and Biochemical Properties

scientific article published on 12 July 2018
A patient with metastatic lung adenocarcinoma harboring concurrent EGFR L858R, EGFR germline T790M, and PIK3CA mutations: the challenge of interpreting results of comprehensive mutational testing in lung cancer

scientific article
MINI01.02: Response and Plasma Genotyping from Phase I/II Trial of Ensartinib (X-396) in Patients (pts) with ALK+ NSCLC: Topic: Medical Oncology

scientific article
Shades of T790M: Intratumor Heterogeneity in EGFR-Mutant Lung Cancer

scientific article published in July 2015
My Cancer Genome: Evaluating an Educational Model to Introduce Patients and Caregivers to Precision Medicine Information

scientific article published on 20 July 2016
Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometry

scientific article published in January 2007
Liquid biopsies reveal the dynamic nature of resistance mechanisms in solid tumors

scientific article published on 01 July 2015
On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation

scientific article published on 22 February 2019
Managing Resistance to EFGR- and ALK-Targeted Therapies

scientific article published on January 2017
Melanoma driver mutations and immune therapy

scientific article published on 10 March 2016
NCCN Working Group report: designing clinical trials in the era of multiple biomarkers and targeted therapies

scientific article
Combating Acquired Resistance to Tyrosine Kinase Inhibitors in Lung Cancer

scientific article published on January 1, 2015
Tumor Heterogeneity and Therapeutic Resistance

scientific article published on January 2016
Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer

scientific article published on 22 August 2019
Established, emerging, and elusive molecular targets in the treatment of lung cancer.

scientific article published on 17 January 2018
Strategies for overcoming EGFR resistance in the treatment of advanced-stage NSCLC

scientific article published on 01 December 2012
P1.44 (also presented as PD2.02): Phase I/II Trial of X-396, A Novel ALK Inhibitor, in Patients With ALK+ NSCLC: Track: Advanced NSCLC.

scientific article
Sequencing Therapy for Genetically Defined Subgroups of Non-Small Cell Lung Cancer

scientific article published on 01 May 2018
New Approaches to SCLC Therapy: From the Laboratory to the Clinic

scientific article published on 01 February 2020
Improved Prognosis and Increased Tumor-Infiltrating Lymphocytes in Patients Who Have SCLC With Neurologic Paraneoplastic Syndromes

scientific article published on 12 June 2019
Small Cell Lung Cancer Transformation as a Mechanism of Resistance to PD-1 Therapy in KRAS-Mutant Lung Adenocarcinoma: A Report of Two Cases

scientific article published on 10 December 2018
Major milestones in translational oncology.

scientific article published on 28 July 2016
Cracking the Code of Resistance across Multiple Lines of ALK Inhibitor Therapy in Lung Cancer

scientific article published on October 2016
Update on HER1-3 in advanced non-small-cell lung cancer

scientific article
COVID-19 and immune checkpoint inhibitors: initial considerations

scientific article published on 01 May 2020
Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting

scientific article published on 2 March 2021
Correction: An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer

scientific article published on 01 February 2019
A Review of Immunotherapy for Stage III and Metastatic Non‐Small Cell Lung Cancer and the Rationale for the ECOG‐ACRIN EA5181 Study

journal article
PD2.02 (also presented as P1.44): Phase I/II Trial of X-396, a Novel ALK Inhibitor, in Patients With ALK+ NSCLC.

scientific article
The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA

scientific article published on 11 October 2019
Stop fRETting the Target: Next-Generation RET Inhibitors Have Arrived

scientific article published on 01 July 2018
N-[18F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer

scientific article published on 02 June 2020
Vulnerability of drug-resistant EML4-ALK rearranged lung cancer to transcriptional inhibition

scientific article published on 17 June 2020
Vitamin D3 Metabolites Demonstrate Prognostic Value in EGFR-Mutant Lung Adenocarcinoma and Can be Deployed to Oppose Acquired Therapeutic Resistance

scientific article published on 13 March 2020
Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion

scientific article published on 17 February 2022
Genomic landscape of a metastatic malignant proliferating tricholemmal tumor and its response to PI3K inhibition

scientific article published on 15 February 2019
Expanding Access to Lung Cancer Clinical Trials by Reducing the Use of Restrictive Exclusion Criteria: Perspectives of a Multistakeholder Working Group

scientific article published on 26 February 2020
Variable Response to ALK Inhibitors in NSCLC with a Novel MYT1L-ALK Fusion

scientific article published on 01 February 2019
A 75-year-old man with progressive bronchioalveolar carcinoma

scientific article published in February 2013
Rapidly fatal pneumonitis from immunotherapy and concurrent SARS-CoV-2 infection in a patient with newly diagnosed lung cancer

scientific article published on 02 May 2020

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