List of works - Didier Auboeuf

A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants.

scientific article

A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors.

scientific article published on 28 February 2014

A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts

scientific article

Alternative Splicing and Cancer ⬇️

scientific article published on May 20, 2012

Alternative mRNA processing sites decrease genetic variability while increasing functional diversity.

scientific article

Alternative splicing and breast cancer.

scientific article published on July 2010

Alternative splicing signatures discriminate ATL cells from untransformed CD4+ counterparts deriving from HTLV-1 infected individuals.

scientific article published on 7 January 2014

Analysis of co-transcriptional RNA processing by RNA-ChIP assay.

scientific article published in January 2012

Candidate gene prioritization with Endeavour.

scientific article published on 30 April 2016

Characterizing the interplay between gene nucleotide composition bias and splicing

scientific article published on 29 November 2019

CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing

scientific article published on January 2004

Complementarity of assembly-first and mapping-first approaches for alternative splicing annotation and differential analysis from RNAseq data.

scientific article published on 9 March 2018

Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes.

scientific article

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor ⬇️

scientific article published on January 23, 2012

Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin.

scientific article published on 04 December 2013

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

scientific article published on 20 April 2010

Genome evolution is driven by gene expression-generated biophysical constraints through RNA-directed genetic variation: A hypothesis

scientific article published on 8 September 2017

HTLV-1 modulates alternative splicing in CD4+ T cells in vivo.

scientific article published on 6 June 2011

Identification of protein features encoded by alternative exons using Exon Ontology.

scientific article published on 18 April 2017

In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin

scientific article published on 3 November 2015

Interplay between coding and exonic splicing regulatory sequences

scientific article published on 08 April 2019

Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1

scientific article published on 16 June 2020

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

scientific article published on 29 May 2011

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy

scientific article published on 19 June 2011

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

scientific article published on 24 February 2016

Nucleosome eviction in mitosis assists condensin loading and chromosome condensation

scientific article published on 6 June 2016

Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).

scientific article published on 12 May 2015

Outcome of children treated with haematopoietic-stem cell transplantations from donors expressing the rare C77G variant of the PTPRC (CD45) gene

scientific article published on 17 February 2011

Physicochemical Foundations of Life that Direct Evolution: Chance and Natural Selection are not Evolutionary Driving Forces

scientific article published on 21 January 2020

Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1

scientific article published on 27 December 2018

Putative RNA-Directed Adaptive Mutations in Cancer Evolution

scientific article published on 10 August 2016

RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation

scientific journal article

Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.

scientific article published on 20 August 2007

Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.

scientific article

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

scientific article published on 11 April 2016

Splicing programs and cancer

scientific article

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

scientific journal article

TET2 exon 2 skipping is an independent favorable prognostic factor for cytogenetically normal acute myelogenous leukemia (AML): TET2 exon 2 skipping in AML.

scientific article published on 16 January 2017

Tax promotes the expression of the alternative spliced isoform CD44v10 by slowing down the elongating RNA polymerase II.

scientific article

The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways

scientific journal article

The RNA helicase DDX17 controls the transcriptional activity of REST and the expression of proneural microRNAs in neuronal differentiation

scientific article published on 01 September 2018

The RNA helicase DDX5 is a reprogramming roadblock.

scientific article published on 27 September 2017

The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export

scientific article

The multiple functions of RNA helicases as drivers and regulators of gene expression.

scientific article published on 2 June 2016

The proto-oncogenic protein TAL1 controls TGF-β1 signaling through interaction with SMAD3.

scientific article published on 14 May 2016

Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism.

scientific article published on 3 May 2017

hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.

scientific article published on 5 February 2013

List of works by Didier Auboeuf

A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants.

A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors.

A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts

Alternative Splicing and Cancer ⬇️

Alternative mRNA processing sites decrease genetic variability while increasing functional diversity.

Alternative splicing and breast cancer.

Alternative splicing signatures discriminate ATL cells from untransformed CD4+ counterparts deriving from HTLV-1 infected individuals.

Analysis of co-transcriptional RNA processing by RNA-ChIP assay.

Candidate gene prioritization with Endeavour.

Characterizing the interplay between gene nucleotide composition bias and splicing

CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing

Complementarity of assembly-first and mapping-first approaches for alternative splicing annotation and differential analysis from RNAseq data.

Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes.

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor ⬇️

Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin.

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

Genome evolution is driven by gene expression-generated biophysical constraints through RNA-directed genetic variation: A hypothesis

HTLV-1 modulates alternative splicing in CD4+ T cells in vivo.

Identification of protein features encoded by alternative exons using Exon Ontology.

In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin

Interplay between coding and exonic splicing regulatory sequences

Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

Nucleosome eviction in mitosis assists condensin loading and chromosome condensation

Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).

Outcome of children treated with haematopoietic-stem cell transplantations from donors expressing the rare C77G variant of the PTPRC (CD45) gene

Physicochemical Foundations of Life that Direct Evolution: Chance and Natural Selection are not Evolutionary Driving Forces

Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1

Putative RNA-Directed Adaptive Mutations in Cancer Evolution

RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation

Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.

Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

Splicing programs and cancer

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

TET2 exon 2 skipping is an independent favorable prognostic factor for cytogenetically normal acute myelogenous leukemia (AML): TET2 exon 2 skipping in AML.

Tax promotes the expression of the alternative spliced isoform CD44v10 by slowing down the elongating RNA polymerase II.

The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways

The RNA helicase DDX17 controls the transcriptional activity of REST and the expression of proneural microRNAs in neuronal differentiation

The RNA helicase DDX5 is a reprogramming roadblock.

The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export

The multiple functions of RNA helicases as drivers and regulators of gene expression.

The proto-oncogenic protein TAL1 controls TGF-β1 signaling through interaction with SMAD3.

Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism.

hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.