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List of works by Paweł Sledź

A three-stage biophysical screening cascade for fragment-based drug discovery.

scientific article

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

scientific article

Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome

scientific article

Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif

scientific article published on 14 November 2019

From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo‐Like Kinase 1 ⬇️

scientific article published on March 29, 2011

High‐Throughput Interrogation of Ligand Binding Mode Using a Fluorescence‐Based Assay ⬇️

scientific article published on June 22, 2012

Ligand retargeting by binding site analogy

scientific article published on 25 April 2019

Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity

scientific article

Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments

scientific article published on 02 March 2020

Structural insights into the molecular mechanism of the m(6)A writer complex

scientific article published on 14 September 2016

Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation ⬇️

scientific article published on April 15, 2013

Structure-Driven Developments of 26S Proteasome Inhibitors

scientific article

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