List of works - Tihomir Tomasić

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

scientific article published on 10 February 2019

Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol.

scientific article published on 31 August 2015

Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists.

scientific article published on 28 May 2014

Benzothiazole-based compounds in antibacterial drug discovery.

scientific article published on 9 October 2017

Comparative evaluation of several docking tools for docking small molecule ligands to DC-SIGN.

scientific article published on 04 June 2015

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors.

scientific article

Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.

scientific article published on 14 December 2017

Diethylstilbestrol-scaffold-based pregnane X receptor modulators

scientific article published on 08 September 2015

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

scientific article published on 8 July 2015

Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors

scientific article

Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.

scientific article published on 15 March 2018

Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations

scientific article published on 20 September 2020

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

scientific article published on 22 February 2017

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.

scientific article

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

scientific article published on 22 December 2020

Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.

scientific article published on 24 August 2016

In vitro bioactivation of bazedoxifene and 2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol in human liver microsomes.

scientific article published on 10 March 2012

Inhibition of Hepatitis C Replication by Targeting the Molecular Chaperone Hsp90: Synthesis and Biological Evaluation of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazole Derivatives

scientific article published on 22 January 2019

Inhibition of O-GlcNAc transferase (OGT) by peptidic hybrids

scientific article published on 18 April 2018

Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors Differs among Cells and Is Not Required for Its Inhibition

scientific article published on 25 July 2020

Ligand- and structure-based virtual screening for clathrodin-derived human voltage-gated sodium channel modulators

scientific article

Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90.

scientific article published on 5 June 2017

Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.

scientific article published on 31 January 2014

MurD enzymes from different bacteria: Evaluation of inhibitors

scientific article published on 15 June 2012

N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation

scientific article

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.

scientific article

New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

scientific article published on 20 May 2019

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity

scientific article published on 10 May 2018

New brominated flame retardants and their metabolites as activators of the pregnane X receptor.

scientific article published on 6 August 2016

Novel state-dependent voltage-gated sodium channel modulators, based on marine alkaloids from Agelas sponges.

scientific article published on 11 August 2013

Peptide microarray analysis of the cross-talk between O-GlcNAcylation and tyrosine phosphorylation

scientific article published on 5 June 2017

Prospects for developing new antibacterials targeting bacterial type IIA topoisomerases.

scientific article published on January 2014

Rational design of balanced dual-targeting antibiotics with limited resistance

scientific article published on 05 October 2020

Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation.

scientific article

STD NMR and molecular modelling insights into interaction of novel mannose-based ligands with DC-SIGN

scientific article published on 18 November 2015

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators

scientific article

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

scientific article

Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents

scientific article published on 27 June 2019

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.

scientific article published on 5 November 2008

Virtual screening for potential inhibitors of bacterial MurC and MurD ligases

scientific article published on 12 June 2011

Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity.

scientific article published on 19 April 2017

List of works by Tihomir Tomasić

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol.

Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists.

Benzothiazole-based compounds in antibacterial drug discovery.

Comparative evaluation of several docking tools for docking small molecule ligands to DC-SIGN.

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors.

Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.

Diethylstilbestrol-scaffold-based pregnane X receptor modulators

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors

Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.

Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.

In vitro bioactivation of bazedoxifene and 2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol in human liver microsomes.

Inhibition of Hepatitis C Replication by Targeting the Molecular Chaperone Hsp90: Synthesis and Biological Evaluation of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazole Derivatives

Inhibition of O-GlcNAc transferase (OGT) by peptidic hybrids

Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors Differs among Cells and Is Not Required for Its Inhibition

Ligand- and structure-based virtual screening for clathrodin-derived human voltage-gated sodium channel modulators

Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90.

Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.

MurD enzymes from different bacteria: Evaluation of inhibitors

N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.

New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity

New brominated flame retardants and their metabolites as activators of the pregnane X receptor.

Novel state-dependent voltage-gated sodium channel modulators, based on marine alkaloids from Agelas sponges.

Peptide microarray analysis of the cross-talk between O-GlcNAcylation and tyrosine phosphorylation

Prospects for developing new antibacterials targeting bacterial type IIA topoisomerases.

Rational design of balanced dual-targeting antibiotics with limited resistance

Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation.

STD NMR and molecular modelling insights into interaction of novel mannose-based ligands with DC-SIGN

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.

Virtual screening for potential inhibitors of bacterial MurC and MurD ligases

Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity.