List of works - Cheryl Scudamore

A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways

scientific article published on 01 December 2018

A simplified necropsy technique for mice: making the most of unscheduled deaths

scientific article published on 29 May 2014

Abdominal fibrosarcoma associated with a retained surgical swab in a dog.

scientific article published on 21 January 2010

Acquiring, recording, and analyzing pathology data from experimental mice: an overview.

scientific article

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess

scientific article

Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue ⬇️

scientific article published on December 1, 2001

Commentary: the role of the toxicologic pathologist in academia.

scientific article published on 19 February 2014

Correlation of histopathology, urinary biomarkers, and gene expression responses following hexachloro-1:3-butadiene-induced acute nephrotoxicity in male Hanover Wistar rats: a 28-day time course study.

scientific article published on 6 November 2012

Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

scientific article published on 06 April 2016

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

scientific article

Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare ⬇️

scientific article

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome

scientific article

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

scientific article

Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues

scientific article published on 26 December 2016

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread

scientific article

Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.

scientific article

Future of disease surveillance.

scientific article published in December 2013

Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression

scientific article

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice.

scientific article published on 28 May 2013

Histochemical and Ultrastructural Modification of Mucosal Mast Cell Granules in Parasitized Mice Lacking the β-Chymase, Mouse Mast Cell Protease-1 ⬇️

scientific article published on August 1, 1998

Histopathological analysis of the respiratory tract.

scientific article published on 11 December 2014

Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread

scientific article published on 01 January 2018

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

scientific article (publication date: 19 June 2014)

Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice

scientific article published on 30 April 2016

Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity

scientific article

Integrating pathology into human disease modelling--how to eat the elephant.

scientific article published on May 2014

International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies

scientific article published on 17 August 2010

International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies.

scientific article published on September 2010

International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies.

scientific article

Laparoscopy for intrauterine insemination and embryo recovery in superovulated ewes at a commercial embryo transfer unit

scientific article published on 01 February 1991

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

scientific article published on 15 May 2020

Modelling invasive group A streptococcal disease using bioluminescence

scientific article

Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background

scientific article published on 31 December 2019

Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury.

scientific article published on 8 September 2011

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

scientific article

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

scientific article

Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models

scientific article published on 01 December 2018

Pharmacological inhibition of FTO.

scientific article published on April 2015

Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function

scientific article published in Nature Communications

Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma.

scientific article published on 18 May 2012

Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity

scientific article published on 24 August 2017

Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines

scientific article

Review of approaches to the recording of background lesions in toxicologic pathology studies in rats.

scientific article published on 21 June 2014

Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner

scientific article

Severe oral ulceration in lambs ⬇️

scientific article published on 01 May 1998

Shared Ageing Research Models (ShARM): a new facility to support ageing research.

scientific article published on 02 October 2013

Systemic silencing of PHD2 causes reversible immune regulatory dysfunction

scientific article published on 04 June 2019

Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene.

scientific article

Ten-minute chat.

scientific article published in March 2016

The Influence of the CTIP Polymorphism, Q418P, on Homologous Recombination and Predisposition to Radiation-Induced Tumorigenesis (mainly rAML) in Mice.

scientific article

The effect of timing of laparoscopic insemination in superovulated ewes, with or without sedation, on the recovery of embryos, their stage of development and subsequent viability

scientific article published on 01 May 1991

The effect of trauma on invasive group A streptococcal disease.

scientific article published on February 2015

The effect of two different levels of progesterone priming on the response of ewes to superovulation

scientific article published on 01 February 1993

The rat mucosal mast cell chymase, RMCP-11, alters epithelial cell monolayer permeability in association with altered distribution of the tight junction proteins ZO-1 and occludin ⬇️

scientific article published on April 1, 1998

Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis.

scientific article published on 3 March 2018

Triggered doxorubicin release in solid tumors from thermosensitive liposome-peptide hybrids: Critical parameters and therapeutic efficacy.

scientific article

Urinary biomarkers in hexachloro‐1:3‐butadiene‐induced acute kidney injury in the female Hanover Wistar rat; correlation of α‐glutathione S‐transferase, albumin and kidney injury molecule‐1 with histopathology and gene expression ⬇️

scientific article published on May 1, 2011

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

scientific article published on 27 November 2017

¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.

scientific article published on 20 April 2015

List of works by Cheryl Scudamore

A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways

A simplified necropsy technique for mice: making the most of unscheduled deaths

Abdominal fibrosarcoma associated with a retained surgical swab in a dog.

Acquiring, recording, and analyzing pathology data from experimental mice: an overview.

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess

Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue ⬇️

Commentary: the role of the toxicologic pathologist in academia.

Correlation of histopathology, urinary biomarkers, and gene expression responses following hexachloro-1:3-butadiene-induced acute nephrotoxicity in male Hanover Wistar rats: a 28-day time course study.

Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare ⬇️

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread

Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.

Future of disease surveillance.

Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice.

Histochemical and Ultrastructural Modification of Mucosal Mast Cell Granules in Parasitized Mice Lacking the β-Chymase, Mouse Mast Cell Protease-1 ⬇️

Histopathological analysis of the respiratory tract.

Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice

Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity

Integrating pathology into human disease modelling--how to eat the elephant.

International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies

International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies.

International recommendations for training future toxicologic pathologists participating in regulatory-type, nonclinical toxicity studies.

Laparoscopy for intrauterine insemination and embryo recovery in superovulated ewes at a commercial embryo transfer unit

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

Modelling invasive group A streptococcal disease using bioluminescence

Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background

Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury.

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models

Pharmacological inhibition of FTO.

Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function

Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma.

Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity

Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines

Review of approaches to the recording of background lesions in toxicologic pathology studies in rats.

Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner

Severe oral ulceration in lambs ⬇️

Shared Ageing Research Models (ShARM): a new facility to support ageing research.

Systemic silencing of PHD2 causes reversible immune regulatory dysfunction

Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene.

Ten-minute chat.

The Influence of the CTIP Polymorphism, Q418P, on Homologous Recombination and Predisposition to Radiation-Induced Tumorigenesis (mainly rAML) in Mice.

The effect of timing of laparoscopic insemination in superovulated ewes, with or without sedation, on the recovery of embryos, their stage of development and subsequent viability

The effect of trauma on invasive group A streptococcal disease.

The effect of two different levels of progesterone priming on the response of ewes to superovulation

The rat mucosal mast cell chymase, RMCP-11, alters epithelial cell monolayer permeability in association with altered distribution of the tight junction proteins ZO-1 and occludin ⬇️

Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis.

Triggered doxorubicin release in solid tumors from thermosensitive liposome-peptide hybrids: Critical parameters and therapeutic efficacy.

Urinary biomarkers in hexachloro‐1:3‐butadiene‐induced acute kidney injury in the female Hanover Wistar rat; correlation of α‐glutathione S‐transferase, albumin and kidney injury molecule‐1 with histopathology and gene expression ⬇️

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.