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List of works by Rksubbarao Malireddi

A comprehensive guide to studying inflammasome activation and cell death

scientific article published on 07 September 2020

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

scientific article published on July 2012

Autophagy is redundant for the host defense against systemic Candida albicans infections.

scientific article

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.

scientific article published on 22 August 2016

Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis

scientific article published on 23 March 2016

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

scientific article published on 11 September 2019

Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection

article

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

scientific article

FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

scientific article published on 22 January 2014

Food for Training-Western Diet and Inflammatory Memory

scientific article published in March 2018

Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.

scientific article

Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection

scientific article published on 03 December 2018

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

scientific article

Galactosaminogalactan activates the inflammasome to provide host protection

scientific article published on 02 December 2020

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.

scientific article published on 6 July 2018

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation

scientific article published on 22 March 2018

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

scientific article published on 28 September 2016

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease

scientific article published on 01 March 2020

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

scientific article published on 13 November 2012

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

scientific article published on 4 May 2015

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

scientific journal article

NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer

scientific article

Publisher Correction: Galactosaminogalactan activates the inflammasome to provide host protection

scientific article published on 21 December 2020

Role of the nlrp3 inflammasome in microbial infection.

scientific article

Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection.

scientific article

SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

scientific article published on 01 September 2018

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.

scientific article

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

scientific article

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation

scientific article published on 26 June 2018

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

scientific journal article

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.

scientific article published on 04 July 2011

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

scientific article published on 16 March 2015

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

scientific article

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

scientific article published on 26 November 2019

ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

scientific article published on 19 May 2022

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death.

scientific article published on 20 June 2017