List of works - Bernhard Fleckenstein

A novel homozygous Fas ligand mutation leads to early protein truncation, abrogation of death receptor and reverse signaling and a severe form of the autoimmune lymphoproliferative syndrome

scientific article published on 24 October 2014

Cell Surface Markers in HTLV-1 Pathogenesis ⬇️

scientific article published on August 16, 2011

Correction: HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop.

scientific article

Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease

scientific article published on 25 June 2015

Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.

scientific article published on 19 September 2016

EBV Negative Lymphoma and Autoimmune Lymphoproliferative Syndrome Like Phenotype Extend the Clinical Spectrum of Primary Immunodeficiency Caused by STK4 Deficiency

Elevated cyclic AMP levels in T lymphocytes transformed by human T-cell lymphotropic virus type 1.

scientific article published on 23 June 2010

Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24.

scientific article published on 29 July 2016

Frequent occurrence of therapeutically reversible CMV-associated encephalopathy during radiotherapy of the brain

scientific article published on 10 June 2016

Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs

scientific article

HIV entry inhibition by the envelope 2 glycoprotein of GB virus C.

scientific article

HIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]

scientific article

Herpesvirus ateles Tio can replace herpesvirus saimiri StpC and Tip oncoproteins in growth transformation of monkey and human T cells

scientific article

Herpesvirus saimiri transformation of human T lymphocytes

scientific article

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

scientific article published on 01 December 2018

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

scientific article

Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels

scientific article published on April 2014

Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood

scientific article published on 29 July 2013

Inhibition of HIV strains by GB virus C in cell culture can be mediated by CD4 and CD8 T-lymphocyte derived soluble factors

scientific article published in August 2005

NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells

scientific article published on 17 June 2008

NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6.

scientific article published on February 2006

No evidence for human papillomavirus infection in focal cortical dysplasia IIb.

scientific article published on 24 December 2014

Peptides derived from a distinct region of GB virus C glycoprotein E2 mediate strain-specific HIV-1 entry inhibition

scientific article

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries

scientific article

Species restriction of Herpesvirus saimiri and Herpesvirus ateles: Human lymphocyte transformation correlates with distinct signaling properties of viral oncoproteins ⬇️

scientific article published on February 25, 2012

Specific antibody deficiency and autoinflammatory disease extend the clinical and immunological spectrum of heterozygous NFKB1 loss-of-function mutations in humans

scientific article published on 30 June 2016

T-cell growth transformation by herpesvirus saimiri is independent of STAT3 activation

scientific article published on May 2005

T-cell transformation and oncogenesis by gamma2-herpesviruses

scientific article

The Latency-Associated Nuclear Antigen Homolog of Herpesvirus Saimiri Inhibits Lytic Virus Replication ⬇️

scientific article published on May 1, 2003

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

scientific article

The transcription elongation factor ELL2 is specifically upregulated in HTLV-1-infected T-cells and is dependent on the viral oncoprotein Tax.

scientific article published on 22 July 2014

The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration

scientific article

The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-kappaB signals.

scientific article published on 7 February 2011

The tumour marker Fascin is strongly induced by Tax of HTLV-1 through NF-κB signals in T lymphocytes

scholarly article by Andrea K Kress et al published 2011 in Retrovirology

The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cells

scientific article

Transduction of Herpesvirus saimiri-Transformed T Cells with Exogenous Genes of Interest.

scientific article

Transformation efficiency by Herpesvirus saimiri is not a limiting factor in clonal CD8pos T cell outgrowth

scientific article published on 17 April 2009

Tyrosine phosphorylation of the Tio oncoprotein is essential for transformation of primary human T cells

scientific article

Upregulation of the transcription elongation factor ELL2 by Tax as a novel mechanism of HTLV-1 gene expression.

scientific article published on 7 January 2014

List of works by Bernhard Fleckenstein

A novel homozygous Fas ligand mutation leads to early protein truncation, abrogation of death receptor and reverse signaling and a severe form of the autoimmune lymphoproliferative syndrome

Cell Surface Markers in HTLV-1 Pathogenesis ⬇️

Correction: HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop.

Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease

Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.

EBV Negative Lymphoma and Autoimmune Lymphoproliferative Syndrome Like Phenotype Extend the Clinical Spectrum of Primary Immunodeficiency Caused by STK4 Deficiency

Elevated cyclic AMP levels in T lymphocytes transformed by human T-cell lymphotropic virus type 1.

Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24.

Frequent occurrence of therapeutically reversible CMV-associated encephalopathy during radiotherapy of the brain

Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs

HIV entry inhibition by the envelope 2 glycoprotein of GB virus C.

HIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]

Herpesvirus ateles Tio can replace herpesvirus saimiri StpC and Tip oncoproteins in growth transformation of monkey and human T cells

Herpesvirus saimiri transformation of human T lymphocytes

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels

Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood

Inhibition of HIV strains by GB virus C in cell culture can be mediated by CD4 and CD8 T-lymphocyte derived soluble factors

NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells

NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6.

No evidence for human papillomavirus infection in focal cortical dysplasia IIb.

Peptides derived from a distinct region of GB virus C glycoprotein E2 mediate strain-specific HIV-1 entry inhibition

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries

Species restriction of Herpesvirus saimiri and Herpesvirus ateles: Human lymphocyte transformation correlates with distinct signaling properties of viral oncoproteins ⬇️

Specific antibody deficiency and autoinflammatory disease extend the clinical and immunological spectrum of heterozygous NFKB1 loss-of-function mutations in humans

T-cell growth transformation by herpesvirus saimiri is independent of STAT3 activation

T-cell transformation and oncogenesis by gamma2-herpesviruses

The Latency-Associated Nuclear Antigen Homolog of Herpesvirus Saimiri Inhibits Lytic Virus Replication ⬇️

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

The transcription elongation factor ELL2 is specifically upregulated in HTLV-1-infected T-cells and is dependent on the viral oncoprotein Tax.

The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration

The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-kappaB signals.

The tumour marker Fascin is strongly induced by Tax of HTLV-1 through NF-κB signals in T lymphocytes

The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cells

Transduction of Herpesvirus saimiri-Transformed T Cells with Exogenous Genes of Interest.

Transformation efficiency by Herpesvirus saimiri is not a limiting factor in clonal CD8pos T cell outgrowth

Tyrosine phosphorylation of the Tio oncoprotein is essential for transformation of primary human T cells

Upregulation of the transcription elongation factor ELL2 by Tax as a novel mechanism of HTLV-1 gene expression.