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List of works by Michele Cea

A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib.

scientific article published on 5 May 2010

A simple cytofluorimetric score may optimize testing for biallelic CEBPA mutations in patients with acute myeloid leukemia

scientific article published on 06 September 2019

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells

scientific article published on 11 May 2015

APO866 activity in hematologic malignancies: a preclinical in vitro study.

scientific article published in June 2009

APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment.

scientific article published on 28 April 2016

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.

scientific article

Author Correction: Fasting-mimicking diet and hormone therapy induce breast cancer regression

scientific article published on 04 December 2020

Autophagy in blood cancers: biological role and therapeutic implications.

scientific article published on September 2013

Biological Insights into Myeloma and Other B Cell Malignancies.

scientific article published on 16 February 2016

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

scientific article

CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.

scientific article published on 16 April 2013

CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation

scientific article published on 16 July 2015

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.

scientific article published on 12 October 2017

Dexamethasone, oxaliplatin and cytarabine (R-DHAOx) as salvage and stem cells mobilizing therapy in relapsed/refractory diffuse large B cell lymphomas

scientific article published on 04 September 2019

Do Cancer Drugs Counteract Neurodegeneration? Repurposing for Alzheimer's Disease.

scientific article published on 7 November 2016

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.

scientific article published on 10 June 2016

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition

scientific article

Early minimal residual disease assessment after AML induction with fludarabine, cytarabine and idarubicin (FLAI) provides the most useful prognostic information

scientific article

Evaluating treatment response of chronic myeloid leukemia: emerging science and technology.

scientific article published on September 2013

Evaluation of prognostic indices in elderly hospitalized patients

scientific article published on 15 June 2016

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

scientific article published on 16 December 2015

Exploiting tumor vulnerabilities: NAD(+)-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies

scientific article published on 19 July 2016

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

scientific article published in May 2015

Fasting-mimicking diet and hormone therapy induce breast cancer regression

scientific article published on 15 July 2020

Fludarabine, High-Dose Cytarabine and Idarubicin-Based Induction May Overcome the Negative Prognostic Impact of <i>FLT3</i>-ITD in <i>NPM1</i> Mutated AML, Irrespectively of <i>FLT3</i>-ITD Allelic Burden

scientific article published on 24 December 2020

Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.

scientific article published on 17 January 2017

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression

scientific article

Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.

scientific article published on 2 March 2018

Intracellular NAD(+) depletion induces autophagic death in multiple myeloma cells.

scientific article published on March 2013

Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis

scientific article published on 21 September 2016

Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma

scientific article published on 19 August 2019

Longitudinal minimal residual disease (MRD) evaluation in acute myeloid leukaemia with NPM1 mutation: from definition of molecular relapse to MRD-driven salvage approach

scientific article published on 26 July 2019

Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma.

scientific article published on 22 October 2015

New insights into biology of chronic myeloid leukemia: implications in therapy.

scientific article published on September 2013

Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience.

scientific article published on June 2013

Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity

scientific article

Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

scientific article

Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma.

scientific article

Nutrients in the Prevention of Alzheimer's Disease

scientific article published on 04 September 2019

Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin

scientific article published on 16 March 2017

Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics

scientific article published on 18 March 2014

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

scientific article published on 19 September 2017

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity.

scientific article published on 10 September 2009

Targeting Inflammation in Primary Cardiovascular Prevention

scientific article

Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.

scientific article

The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival

scientific article published on 5 January 2016

The Novel Phosphatidylinositol-3-Kinase (PI3K) Inhibitor Alpelisib Effectively Inhibits Growth of PTEN-Haploinsufficient Lipoma Cells

scientific article published on 17 October 2019

Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response.

scientific article published on 25 April 2015

Validation of the Photography Method for Nutritional Intake Assessment in Hospitalized Elderly Subjects.

scientific article published in January 2017

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