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List of works by Carlo Rodolfo Largiadèr

A new DPYD genotyping assay for improving the safety of 5-fluorouracil therapy ⬇️

scientific article published on August 23, 2012

Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response.

scientific article

Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration.

scientific article published on 17 January 2017

Bevacizumab, Pemetrexed, and Cisplatin, or Bevacizumab and Erlotinib for Patients With Advanced Non-Small-Cell Lung Cancer Stratified by Epidermal Growth Factor Receptor Mutation: Phase II Trial SAKK19/09.

scientific article published on 5 March 2015

Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early-onset fluoropyrimidine toxicity

scientific article published on 27 June 2014

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

scientific article

Comparative evaluation of the My5-FU™ immunoassay and LC-MS/MS in monitoring the 5-fluorouracil plasma levels in cancer patients.

scientific article

Dihydropyrimidinase and β-ureidopropionase gene variation and severe fluoropyrimidine-related toxicity

scientific article published on 05 August 2015

Dihydropyrimidine Dehydrogenase Gene as a Major Predictor of Severe 5-Fluorouracil Toxicity ⬇️

scientific article published on September 1, 2011

Eutrophication causes speciation reversal in whitefish adaptive radiations.

scientific article

Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study ⬇️

scientific article published on November 9, 2012

Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5-fluorouracil toxicity

scientific article published on 30 March 2021

High prevalence of hereditary thrombotic thrombocytopenic purpura in central Norway: from clinical observation to evidence.

scientific article

How normal is abnormal? Discrimination between deformations and natural variation in gonad morphology of European whitefish Coregonus lavaretus

scientific article published on 01 May 2009

Increased erythroferrone levels in malarial anaemia

scientific article published on 26 January 2024

Influence of CYP3A5 genetic variation on everolimus maintenance dosing after cardiac transplantation.

scientific article

LC‐MS/MS method for simultaneous analysis of uracil, 5,6‐dihydrouracil, 5‐fluorouracil and 5‐fluoro‐5,6‐dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients ⬇️

scientific article published on March 27, 2012

Mutation screening of the medium-chain acyl-CoA dehydrogenase (MCAD) and the ornithine transcarbamylase (OTC) genes by multiplex PCR amplification and sequencing

scientific article published on 01 January 2009

Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression.

scientific article published on 30 April 2015

Partial expression of ornithine transcarbamylase deficiency in an Egyptian female carrier.

scientific article published on 31 October 2013

Patterns of morphological changes and hybridization between sympatric whitefish morphs (Coregonus spp.) in a Swiss lake: a role for eutrophication?

scientific article published in May 2010

Phenotypic and clinical implications of variants in the dihydropyrimidine dehydrogenase gene

scientific article published on 12 January 2016

Phylogeography of bleaks Alburnus spp. (Cyprinidae) in Italy, based on cytochrome b data.

scientific article

Predicting 5-fluorouracil toxicity: DPD genotype and 5,6-dihydrouracil:uracil ratio

scientific article published on 01 September 2014

SNPs and Haplotypes in DPYD and Outcome of Capecitabine-Letter

scientific article published on 30 August 2011

Sequence Capture and Next-Generation Resequencing of Multiple Tagged Nucleic Acid Samples for Mutation Screening of Urea Cycle Disorders ⬇️

scientific article published on November 10, 2010

The impact of ABCC11 polymorphisms on the risk of early-onset fluoropyrimidine toxicity

scientific article published on 22 March 2016

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