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List of works by Sara Checa

A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach.

scientific article published on 15 November 2008

A review on computer modeling of bone piezoelectricity and its application to bone adaptation and regeneration

scientific article published on 26 July 2019

Age-Related Changes in the Mechanical Regulation of Bone Healing Are Explained by Altered Cellular Mechanoresponse

scientific article published on 29 July 2019

Aging Leads to a Dysregulation in Mechanically Driven Bone Formation and Resorption

scientific article published on 9 April 2015

Anatomic grooved stem mitigates strain shielding compared to established total hip arthroplasty stem designs in finite-element models

scientific article published in Scientific Reports

Computational Modeling to Quantify the Contributions of VEGFR1, VEGFR2, and Lateral Inhibition in Sprouting Angiogenesis

scientific article published on 27 March 2019

Computational analyses of different intervertebral cages for lumbar spinal fusion.

scientific article published on 30 June 2015

Diminished response to in vivo mechanical loading in trabecular and not cortical bone in adulthood of female C57Bl/6 mice coincides with a reduction in deformation to load.

scientific article published in May 2013

Effect of cell seeding and mechanical loading on vascularization and tissue formation inside a scaffold: a mechano-biological model using a lattice approach to simulate cell activity

scientific article published on 01 December 2009

Effect of in vivo loading on bone composition varies with animal age

scientific article

Examining tissue composition, whole-bone morphology and mechanical behavior of GorabPrx1 mice tibiae: A mouse model of premature aging

scientific article published on 25 October 2017

Femoral head necrosis: A finite element analysis of common and novel surgical techniques.

scientific article published on 6 July 2017

In vivo tracking of segmental bone defect healing reveals that callus patterning is related to early mechanical stimuli ⬇️

scientific article published on November 2, 2012

Inter-species investigation of the mechano-regulation of bone healing: comparison of secondary bone healing in sheep and rat.

scientific article

Investigation of different cage designs and mechano-regulation algorithms in the lumbar interbody fusion process - a finite element analysis

scientific article published on 15 February 2014

Machine learning techniques for the optimization of joint replacements: Application to a short-stem hip implant.

scientific article published on 5 September 2017

Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep.

scientific article published in January 2018

Mineralizing surface is the main target of mechanical stimulation independent of age: 3D dynamic in vivo morphometry.

scientific article published on 2 June 2014

Monitoring in vivo (re)modeling: a computational approach using 4D microCT data to quantify bone surface movements.

scientific article

Multiscale Modeling of Bone Healing: Toward a Systems Biology Approach.

scientific article

Physiological joint line total knee arthroplasty designs are especially sensitive to rotational placement - A finite element analysis

scientific article

Relationship between nanoscale mineral properties and calcein labeling in mineralizing bone surfaces

scientific article published in August 2014

Sclerostin-neutralizing antibody treatment enhances bone formation but does not rescue mechanically-induced delayed healing.

scientific article published on 25 April 2018

Shaping scaffold structures in rapid manufacturing implants: a modeling approach toward mechano-biologically optimized configurations for large bone defect.

scientific article

Simulation of angiogenesis and cell differentiation in a CaP scaffold subjected to compressive strains using a lattice modeling approach

scientific article published on 06 December 2009

Skeletal maturation substantially affects elastic tissue properties in the endosteal and periosteal regions of loaded mice tibiae.

scientific article published on 18 April 2015

Skeletal maturity leads to a reduction in the strain magnitudes induced within the bone: a murine tibia study.

scientific article published on 20 November 2014

Sost deficiency leads to reduced mechanical strains at the tibia midshaft in strain-matched in vivo loading experiments in mice.

scientific article published in April 2018

Sost deficiency led to a greater cortical bone formation response to mechanical loading and altered gene expression.

scientific article published on 25 August 2017

Strain shielding inspired re-design of proximal femoral stems for total hip arthroplasty.

scientific article published on 8 February 2017

The Periosteal Bone Surface is Less Mechano-Responsive than the Endocortical

scientific article

The emergence of extracellular matrix mechanics and cell traction forces as important regulators of cellular self-organization.

scientific article published on 10 April 2014

The influence of age on adaptive bone formation and bone resorption.

scientific article published on 13 August 2014

Tissue differentiation in an in vivo bioreactor: in silico investigations of scaffold stiffness

scientific article published on 01 August 2010

Tomography-Based Quantification of Regional Differences in Cortical Bone Surface Remodeling and Mechano-Response.

scientific article

Variability observed in mechano-regulated in vivo tissue differentiation can be explained by variation in cell mechano-sensitivity

scientific article published on 05 March 2011

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